Patents by Inventor Abhijit De

Abhijit De has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ASSAY FOR DETERMINING TARGET ENGAGEMENT IN REAL-TIME IN LIVING SYSTEMS
    Publication number: 20220298541
    Abstract: The present disclosure relates to an assay for determining drug-target engagement in real-time. Specifically, the present disclosure provides a method for determining drug candidate-target interaction in real-time in living systems using Activity-based Reporter Gene Technology-Bioluminescence Resonance Energy Transfer (AbRGT-BRET) based assay. The said assay is useful for High Throughput Screening of compounds to a specific target.
    Type: Application
    Filed: March 18, 2022
    Publication date: September 22, 2022
    Applicant: Indian Institute of Science Education and Research
    Inventors: Britto S. SANDANARAJ, Punita BATHLA, Abhijit DE, Aaiyas MUJAWAR
  • Bioluminescence resonance energy transfer (BRET) systems and methods of use thereof
    Patent number: 7842469
    Abstract: Briefly described, embodiments of this disclosure include bioluminescence resonance energy transfer (BRET) systems, methods of detecting a protein-protein interaction, noninvasive methods for detecting the interaction of a first protein with a second protein within a living animal, methods to determine the efficacy of a test compound administered to modulate the interaction of a first protein with a second protein in a living animal, BRET vectors, kits relating to each of the above, transgenic cell or progeny thereof and/or animals relating to each of the above, and the like.
    Type: Grant
    Filed: February 5, 2009
    Date of Patent: November 30, 2010
    Assignee: Stanford University
    Inventors: Sanjiv S. Gambhir, Abhijit De
  • BIOLUMINESCENCE RESONANCE ENERGY TRANSFER (BRET) SYSTEMS AND METHODS OF USE THEREOF
    Publication number: 20100047813
    Abstract: Briefly described, embodiments of this disclosure include bioluminescence resonance energy transfer (BRET) systems, methods of detecting a protein-protein interaction, noninvasive methods for detecting the interaction of a first protein with a second protein within a living animal, methods to determine the efficacy of a test compound administered to modulate the interaction of a first protein with a second protein in a living animal, BRET vectors, kits relating to each of the above, transgenic cell or progeny thereof and/or animals relating to each of the above, and the like.
    Type: Application
    Filed: February 5, 2009
    Publication date: February 25, 2010
    Inventors: Sanjiv S. Gambhir, Abhijit De
  • Bioluminescence resonance energy transfer (BRET) systems and methods of use thereof
    Patent number: 7507565
    Abstract: Briefly described, embodiments of this disclosure include bioluminescence resonance energy transfer (BRET) systems, methods of detecting a protein-protein interaction, noninvasive methods for detecting the interaction of a first protein with a second protein within a living animal, methods to determine the efficacy of a test compound administered to modulate the interaction of a first protein with a second protein in a living animal, BRET vectors, kits relating to each of the above, transgenic cell or progeny thereof and/or animals relating to each of the above, and the like.
    Type: Grant
    Filed: March 10, 2006
    Date of Patent: March 24, 2009
    Assignee: Stanford University
    Inventors: Sanjiv S. Gambhir, Abhijit De
  • Bisdeoxycoelenterazine derivatives, methods of use, and BRET2 systems
    Publication number: 20090075309
    Abstract: Embodiments of the present disclosure provide for: compositions, BRET systems, kits, and the like.
    Type: Application
    Filed: September 8, 2008
    Publication date: March 19, 2009
    Inventors: Sanjiv S. Gambhir, Jelena Levi, Abhijit De
  • Bioluminescence resonance energy transfer (BRET) systems and methods of use thereof
    Publication number: 20070077609
    Abstract: Briefly described, embodiments of this disclosure include bioluminescence resonance energy transfer (BRET) systems, methods of detecting a protein-protein interaction, noninvasive methods for detecting the interaction of a first protein with a second protein within a living animal, methods to determine the efficacy of a test compound administered to modulate the interaction of a first protein with a second protein in a living animal, BRET vectors, kits relating to each of the above, transgenic cell or progeny thereof and/or animals relating to each of the above, and the like.
    Type: Application
    Filed: March 10, 2006
    Publication date: April 5, 2007
    Inventors: Sanjiv Gambhir, Abhijit De
  • Gum based chewing product and process for preparing the same
    Publication number: 20040107971
    Abstract: A gum based chewing product, particularly a chewing/bubble gum, contains a synthetic or natural betel nut source, an alkaloid-like composition such as nicotine or other such alkaloids like caffeine, theine etc. from natural or synthetic origin for its source. The product preferably has taste enhancers like lime and/or catechu. A process for preparing the gum based chewing product. The product has improved high smoothness, less saliva generation, excellent overall taste and chewing properties. The gum pieces deliver 1 to 12.6 mg of nicotine per piece.
    Type: Application
    Filed: September 16, 2003
    Publication date: June 10, 2004
    Inventor: Abhijit De