Patents by Inventor Abhijit Guha

Abhijit Guha has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CLASSIFYING OUT-OF-DISTRIBUTION DATA USING A CONTRASTIVE LOSS
    Publication number: 20230107505
    Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for training a neural network to (i) generate accurate network outputs for a machine learning task and (ii) generate intermediate outputs that can be used to reliably classify out-of-distribution inputs.
    Type: Application
    Filed: June 4, 2021
    Publication date: April 6, 2023
    Inventors: Rudy Bunel, Jim Huibrecht Winkens, Abhijit Guha Roy, Olaf Ronneberger, Seyed Mohammadali Eslami, Ali Taylan Cemgil, Simon Kohl
  • TUMOR CELL-DERIVED MICROVESICLES
    Publication number: 20220187300
    Abstract: The present invention relates to a method for diagnosis of cancer and for monitoring the progression of cancer and/or the therapeutic efficacy of an anticancer treatment in a sample of a subject by detecting oncogenic and cancer related proteins in microvesicles, and to the use of an agent blocking exchange of microvesicles for treating cancer.
    Type: Application
    Filed: July 23, 2021
    Publication date: June 16, 2022
    Inventors: Janusz RAK, Khalid AL-NEDAWI, Brian MEEHAN, Abhijit GUHA
  • TUMOR CELL-DERIVED MICROVESICLES
    Publication number: 20200141936
    Abstract: The present invention relates to a method for diagnosis of cancer and for monitoring the progression of cancer and/or the therapeutic efficacy of an anticancer treatment in a sample of a subject by detecting oncogenic and cancer related proteins in microvesicles, and to the use of an agent blocking exchange of microvesicles for treating cancer.
    Type: Application
    Filed: June 13, 2019
    Publication date: May 7, 2020
    Inventors: Janusz RAK, Khalid AL-NEDAWI, Brian MEEHAN, Abhijit GUHA
  • Tumor cell-derived microvesicles
    Patent number: 10352935
    Abstract: The present invention relates to a method for diagnosis of cancer and for monitoring the progression of cancer and/or the therapeutic efficacy of an anti-cancer treatment in a sample of a subject by detecting oncogenic and cancer related proteins in microvesicles, and to the use of an agent blocking exchange of microvesicles for treating cancer.
    Type: Grant
    Filed: January 12, 2015
    Date of Patent: July 16, 2019
    Assignees: THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY, THE HOSPITAL FOR SICK CHILDREN
    Inventors: Janusz Rak, Khalid Al-Nedawi, Brian Meehan, Abhijit Guha
  • Tumor cell-derived microvesicles
    Patent number: 10317407
    Abstract: The present invention relates to a method for diagnosis of cancer and for monitoring the progression of cancer and/or the therapeutic efficacy of an anti-cancer treatment in a sample of a subject by detecting oncogenic proteins in microvesicles, and to the use of an agent blocking exchange of microvesicles for treating cancer.
    Type: Grant
    Filed: October 29, 2015
    Date of Patent: June 11, 2019
    Assignees: THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY, THE HOSPITAL FOR SICK CHILDREN
    Inventors: Janusz Rak, Khalid Al-Nedawi, Brian Meehan, Abhijit Guha
  • TUMOR CELL-DERIVED MICROVESICLES
    Publication number: 20160245812
    Abstract: The present invention relates to a method for diagnosis of cancer and for monitoring the progression of cancer and/or the therapeutic efficacy of an anti-cancer treatment in a sample of a subject by detecting oncogenic proteins in microvesicles, and to the use of an agent blocking exchange of microvesicles for treating cancer.
    Type: Application
    Filed: October 29, 2015
    Publication date: August 25, 2016
    Inventors: Janusz RAK, Khalid AL-NEDAWI, Brian MEEHAN, Abhijit GUHA
  • Tumor cell-derived microvesicles
    Patent number: 9186405
    Abstract: The present invention relates to a method for diagnosis of cancer and for monitoring the progression of cancer and/or the therapeutic efficacy of an anti-cancer treatment in a sample of a subject by detecting oncogenic proteins in microvesicles, and to the use of an agent blocking exchange of microvesicles for treating cancer.
    Type: Grant
    Filed: August 8, 2008
    Date of Patent: November 17, 2015
    Assignees: THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY, THE HOSPITAL FOR SICK CHILDREN
    Inventors: Janusz Rak, Khalid Al-Nedawi, Brian Meehan, Abhijit Guha
  • TUMOR CELL-DERIVED MICROVESICLES
    Publication number: 20150293101
    Abstract: The present invention relates to a method for diagnosis of cancer and for monitoring the progression of cancer and/or the therapeutic efficacy of an anti-cancer treatment in a sample of a subject by detecting oncogenic and cancer related proteins in microvesicles, and to the use of an agent blocking exchange of microvesicles for treating cancer.
    Type: Application
    Filed: January 12, 2015
    Publication date: October 15, 2015
    Inventors: Janusz RAK, Khalid AL-NEDAWI, Brian MEEHAN, Abhijit GUHA
  • TUMOR CELL-DERIVED MICROVESICLES
    Publication number: 20130203081
    Abstract: The present invention relates to a method for diagnosis of cancer and for monitoring the progression of cancer and/or the therapeutic efficacy of an anti-cancer treatment in a sample of a subject by detecting oncogenic and cancer related proteins in microvesicles, and to the use of an agent blocking exchange of microvesicles for treating cancer.
    Type: Application
    Filed: April 13, 2011
    Publication date: August 8, 2013
    Inventors: Janusz Rak, Khalid Al-Nedawi, Brian Meehan, Abhijit Guha
  • TUMOR CELL-DERIVED MICROVESICLES
    Publication number: 20120070848
    Abstract: The present invention relates to a method for diagnosis of cancer and for monitoring the progression of cancer and/or the therapeutic efficacy of an anti-cancer treatment in a sample of a subject by detecting oncogenic proteins in microvesicles, and to the use of an agent blocking exchange of microvesicles for treating cancer.
    Type: Application
    Filed: August 8, 2008
    Publication date: March 22, 2012
    Applicants: The Royal Institution for the Advancement of Learning/McGill University, University of Toronto
    Inventors: Janusz Rak, Khalid Al-Nedawi, Brian Meehan, Abhijit Guha
  • TUMOR CELL-DERIVED MICROVESICLES
    Publication number: 20100255514
    Abstract: The present invention relates to a method for diagnosis of cancer and for monitoring the progression of cancer and/or the therapeutic efficacy of an anti-cancer treatment in a sample of a subject by detecting oncogenic and cancer related proteins in microvesicles, and to the use of an agent blocking exchange of microvesicles for treating cancer.
    Type: Application
    Filed: April 13, 2010
    Publication date: October 7, 2010
    Applicant: THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/McGILL UNIVERSITY
    Inventors: Janusz RAK, Khalid AL-NEDAWI, Brian MEEHAN, Abhijit GUHA
  • Method of quantitating GTP and GDP bound to a G protein and uses thereof
    Patent number: 5741635
    Abstract: The invention features methods for measuring the total amounts of G protein-bound GDP and GTP in mammalian cells and tissue. The method of the invention is advantageous over conventional methods in that the cells need not be exposed to phosphate-free growth conditions, which can adversely affect the accuracy of the GTP determination. Moreover, the method does not require exposure of the cells to radiolabelled phosphate in the growth medium. Standardized amounts of G protein-bound GDP and GTP are determined relative to non-nuclear cellular protein content or cellular DNA content, allowing comparison of results across different cell types. The method is particularly applicable to the detection of Ras protein bound GTP and GDP.
    Type: Grant
    Filed: January 30, 1996
    Date of Patent: April 21, 1998
    Assignees: Mount Sinai Hospital Corporation, The Regents of the University of California
    Inventors: Gerry R. Boss, Abhijit Guha, Jurgen S. Scheele, Anthony J. Pawson