Patents by Inventor Abhijit Mishra

Abhijit Mishra has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Amphiphilic substances and functionalized lipid vesicles including the same
    Patent number: 8415461
    Abstract: An amphiphilic substance includes a hydrophobic group, and a polynucleotide group attached to the hydrophobic group. The polynucleotide group includes a first polynucleotide segment and a second polynucleotide segment. The first and second polynucleotide segments are at least partially complementary and are bound together by interactions including base pairing. At least one of the first and second segments includes at least one of an aptamer and a nucleic acid-based enzyme. A lipid vesicle may include the amphiphilic substance, a first polar lipid that is an unstable vesicle former, and a polar liquid. Upon exposure to a rupture agent, the vesicle may rupture, releasing the contents of the vesicle. Substances that may be released from the vesicle include bioactive agents, such as drug agents.
    Type: Grant
    Filed: January 16, 2008
    Date of Patent: April 9, 2013
    Assignee: The Board of Trustees of the University of Illinois
    Inventors: Yi Lu, Gerard Wong, Mehmet Veysel Yigit, Abhijit Mishra
  • AMPHIPHILIC SUBSTANCES AND FUNCTIONALIZED LIPID VESICLES INCLUDING THE SAME
    Publication number: 20100166842
    Abstract: An amphiphilic substance includes a hydrophobic group, and a polynucleotide group attached to the hydrophobic group. The polynucleotide group includes a first polynucleotide segment and a second polynucleotide segment. The first and second polynucleotide segments are at least partially complementary and are bound together by interactions including base pairing. At least one of the first and second segments includes at least one of an aptamer and a nucleic acid-based enzyme. A lipid vesicle may include the amphiphilic substance, a first polar lipid that is an unstable vesicle former, and a polar liquid. Upon exposure to a rupture agent, the vesicle may rupture, releasing the contents of the vesicle. Substances that may be released from the vesicle include bioactive agents, such as drug agents.
    Type: Application
    Filed: January 16, 2008
    Publication date: July 1, 2010
    Inventors: Yi Lu, Gerard Wong, Mehmet Veysel Yigit, Abhijit Mishra