Patents by Inventor Abhimanyu Paraskar

Abhimanyu Paraskar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FORMULATIONS
    Publication number: 20200037638
    Abstract: The invention provides for cannabinoid formulations, including self-emulsifying formulations and micellar dispersions, as well as methods of making and using the same. The formulations comprise a cannabinoid and surfactant. The formulations have improved dissolution, stability, and pharmacokinetics, including absorption and/or oral bioavailability. The invention also provides for formulations comprising at least one active ingredient, including self-emulsifying formulations and micellar dispersions, as well as methods of making and using the same. The formulations comprise a least one active ingredient and surfactant.
    Type: Application
    Filed: August 12, 2019
    Publication date: February 6, 2020
    Inventors: William Stephen Faraci, Stephen E. Zale, Abhimanyu Paraskar, Tuna Yucel, Nicholas J. Boylan
  • Nanoscale platinum compounds and methods of use thereof
    Patent number: 10512696
    Abstract: The invention is directed to biocompatible conjugated polymer nanoparticles including a copolymer backbone, a plurality of sidechains covalently linked to said backbone, and a plurality of platinum compounds dissociably linked to said backbone. The invention is also directed to dicarbonyl-lipid compounds wherein a platinum compound is dissociably linked to the dicarbonyl compound. The invention is also directed to methods of treating cancer or metastasis. The methods includes selecting a subject in need of treatment for cancer or metastasis and administering to the subject an effective amount of any of the nanoparticles, compounds, or compositions of the invention.
    Type: Grant
    Filed: June 15, 2016
    Date of Patent: December 24, 2019
    Assignee: THE BRIGHAM AND WOMEN'S HOSPITAL, INC.
    Inventors: Shiladitya Sengupta, Abhimanyu Paraskar, Shivani Soni, Sudipta Basu, Poulomi Sengupta
  • Metabolically-activated drug conjugates to overcome resistance in cancer therapy
    Patent number: 10300070
    Abstract: Described are combination therapies and metabolically-activated drug conjugates and their use in treating cancer in subjects.
    Type: Grant
    Filed: March 27, 2015
    Date of Patent: May 28, 2019
    Assignee: The Brigham and Women's Hospital, Inc.
    Inventors: Aaron Goldman, Shiladitya Sengupta, Abhimanyu Paraskar
  • METABOLICALLY-ACTIVATED DRUG CONJUGATES TO OVERCOME RESISTANCE IN CANCER THERAPY
    Publication number: 20170105998
    Abstract: Described are combination therapies and metabolically-activated drug conjugates and their use in treating cancer in subjects.
    Type: Application
    Filed: March 27, 2015
    Publication date: April 20, 2017
    Inventors: Aaron Goldman, Shiladitya Sengupta, Abhimanyu Paraskar
  • NANOSCALE PLATINUM COMPOUNDS AND METHODS OF USE THEREOF
    Publication number: 20160367682
    Abstract: The invention is directed to biocompatible conjugated polymer nanoparticles including a copolymer backbone, a plurality of sidechains covalently linked to said backbone, and a plurality of platinum compounds dissociably linked to said backbone. The invention is also directed to dicarbonyl-lipid compounds wherein a platinum compound is dissociably linked to the dicarbonyl compound. The invention is also directed to methods of treating cancer or metastasis. The methods includes selecting a subject in need of treatment for cancer or metastasis and administering to the subject an effective amount of any of the nanoparticles, compounds, or compositions of the invention.
    Type: Application
    Filed: June 15, 2016
    Publication date: December 22, 2016
    Applicant: THE BRIGHAM AND WOMEN'S HOSPITAL, INC.
    Inventors: Shiladitya SENGUPTA, Abhimanyu PARASKAR, Shivani SONI, Sudipta BASU, Poulomi SENGUPTA
  • Nanoscale platinum compounds and methods of use thereof
    Patent number: 9393227
    Abstract: The invention is directed to biocompatible conjugated polymer nanoparticles including a copolymer backbone, a plurality of sidechains covalently linked to said backbone, and a plurality of platinum compounds dissociably linked to said backbone. The invention is also directed to dicarbonyl-lipid compounds wherein a platinum compound is dissociably linked to the dicarbonyl compound. The invention is also directed to methods of treating cancer or metastasis. The methods includes selecting a subject in need of treatment for cancer or metastasis and administering to the subject an effective amount of any of the nanoparticles, compounds, or compositions of the invention.
    Type: Grant
    Filed: February 4, 2010
    Date of Patent: July 19, 2016
    Assignee: THE BRIGHAM AND WOMEN'S HOSPITAL, INC.
    Inventors: Shiladitya Sengupta, Abhimanyu Paraskar, Shivani Soni, Sudipta Basu, Poulomi Sengupta
  • NANOSCALE PLATINUM COMPOUNDS AND METHODS OF USE THEREOF
    Publication number: 20120189571
    Abstract: The invention is directed to biocompatible conjugated polymer nanoparticles including a copolymer backbone, a plurality of sidechains covalently linked to said backbone, and a plurality of platinum compounds dissociably linked to said backbone. The invention is also directed to dicarbonyl-lipid compounds wherein a platinum compound is dissociably linked to the dicarbonyl compound. The invention is also directed to methods of treating cancer or metastasis. The methods includes selecting a subject in need of treatment for cancer or metastasis and administering to the subject an effective amount of any of the nanoparticles, compounds, or compositions of the invention.
    Type: Application
    Filed: February 4, 2010
    Publication date: July 26, 2012
    Applicant: THE BRIGHAM AND WOMEN'S HOSPITAL., INC.
    Inventors: Shiladitya Sengupta, Abhimanyu Paraskar, Shivani Soni, Sudipta Basu, Poulomi Sengupta