Patents by Inventor Abid Hamid

Abid Hamid has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 10-substituted colchicinoids as potent anticancer agents
    Patent number: 9868695
    Abstract: The present invention relates to the compounds of formula I wherein R is as herein described. The present invention particularly relates to synthesis and antiproliferative activity of 10-substituted colchicinoids. Compounds of the invention can be used for prevention or in the treatment of cancer disease.
    Type: Grant
    Filed: October 14, 2015
    Date of Patent: January 16, 2018
    Assignee: Council of Scientific & Industrial Research
    Inventors: Ram A. Vishwakarma, Sandip B. Bharate, Ajay Kumar, Baljinder Singh, Ashok Kumar, Shashi Bhushan, Abid Hamid, Prashant Joshi, Santosh K. Guru, Suresh Kumar, Aashiq Hussain, Asif K. Qazi, Sonali S. Bharate, Parduman Sharma, Ajit K. Saxena, Dilip M. Mondhe, Girish Mahajan, Zahoor Wani
  • Chromone alkaloid dysoline for the treatment of cancer and inflammatory disorders
    Patent number: 9776989
    Abstract: The present invention relates to novel chromone alkaloid of formula 1 isolated from the plant Dysoxylum binectariferum. The compound 5,7-dihydroxy-6-(3-hydroxy-1-methylpiperidin-4-yl)-2-methyl-4H-chromen-4-one, is found to be a potential inhibitor of cell growth and proliferation and also inhibits production of pro-inflammatory cytokines. The formulations of this particular compound can be used for treatment of cancer and inflammation.
    Type: Grant
    Filed: March 31, 2014
    Date of Patent: October 3, 2017
    Assignee: COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH
    Inventors: Ram Asrey Vishwakarma, Shreyans Kumar Jain, Sandip Bibishan Bharate, Abid Hamid Dar, Anamika Khajuria, Samdarshi Meena, Sunil Kumar Bhola, Asif Khurshid Qazi, Aashiq Hussain, Tabasum Sidi, Shaanker Ramanan Uma, Gudasalamani Ravikanth, Ramesh Vasudeva, Kumara Patel Mohana, Kotiganahalli Narayanagowda Ganeshaiah
  • 10-SUBSTITUTED COLCHICINOIDS AS POTENT ANTICANCER AGENTS
    Publication number: 20170226051
    Abstract: The present invention relates to the compounds of formula I wherein R is as herein described. The present invention particularly relates to synthesis and antiproliferative activity of 10-substituted colchicinoids. Compounds of the invention can be used for prevention or in the treatment of cancer disease.
    Type: Application
    Filed: October 14, 2015
    Publication date: August 10, 2017
    Inventors: Ram A. Vishwakarma, Sandip B. Bharate, Ajay Kumar, Baljinder Singh, Ashok Kumar, Shashi Bhushan, Abid Hamid, Prashant Joshi, Santosh K. Guru, Suresh Kumar, Aashiq Hussain, Asif K. Qazi, Sonali S. Bharate, Parduman Sharma, Ajit K. Saxena, Dilip M. Mondhe, Girish Mahajan, Zahoor Wani
  • Brachiatin D and process for production thereof
    Patent number: 9624266
    Abstract: The present invention relates to a peptaibol having sequence AcAib-Asn-Aib-Leu-Aib-Pro-Aib-Asn-Leu-Pro-Ileuol, isolated from endophytic fungus Trichoderma longibrachiatum having accession number MTCC 5721. The peptaibol is named as brachiating D. The present also related to a process for isolating the peptaibol from and use of the peptaibol as a pharmacologically active compound as a strong immunosuppressants and as an anticancer agents.
    Type: Grant
    Filed: August 29, 2014
    Date of Patent: April 18, 2017
    Assignee: Council of Scientific & Industrial Research
    Inventors: Deepika Singh, Jai Prakash Sharma, Sundeep Jaglan, Abid Hamid Dar, Anamika Khajuria, Varun Pratap Singh, Ram Asrey Vishwakarma
  • Brachiatin D and Process for Production Thereof
    Publication number: 20160215017
    Abstract: The present invention relates to a peptaibol having sequence AcAib-Asn-Aib-Leu-Aib-Pro-Aib-Asn-Leu-Pro-Ileuol, isolated from endophytic fungus Trichoderma longibrachiatum having accession number MTCC 5721. The peptaibol is named as brachiating D. The present also related to a process for isolating the peptaibol from and use of the peptaibol as a pharmacologically active compound as a strong immunosuppressants and as an anticancer agents.
    Type: Application
    Filed: August 29, 2014
    Publication date: July 28, 2016
    Applicant: COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH
    Inventors: Deepika SINGH, Jai Prakash SHARMA, Sundeep JAGLAN, Abid Hamid DAR, Anamika KHAJURIA, Varun Pratap SINGH, Ram Asrey VISHWAKARMA
  • NOVEL CHROMONE ALKALOID DYSOLINE FOR THE TREATMENT OF CANCER AND INFLAMMATORY DISORDERS
    Publication number: 20160046611
    Abstract: The present invention relates to novel chromone alkaloid of formula 1 isolated from the plant Dysoxylum binectariferum. The compound 5,7-dihydroxy-6-(3-hydroxy-1-methylpiperidin-4-yl)-2-methyl-4H-chromen-4-one, is found to be a potential inhibitor of cell growth and proliferation and also inhibits production of pro-inflammatory cytokines. The formulations of this particular compound can be used for treatment of cancer and inflammation.
    Type: Application
    Filed: March 31, 2014
    Publication date: February 18, 2016
    Inventors: Ram Asrey Vishwakarma, Shreyans Kumar Jain, Sandip Bibishan Bharate, Abid Hamid Dar, Anamika Khajuria, Samdarshi Meena, Sunil Kumar Bhola, Asif Khurshid Qazi, Aashiq Hussain, Tabasum Sidi, Shaanker Ramanan Uma, Gudasalamani Ravikanth, Ramesh Vasudeva, Kumara Patel Mohana, Kotiganahalli Narayanagowda Ganeshaiah
  • Boronic acid bearing liphagane compounds as inhibitors of P13K-? and/or ?
    Patent number: 9206201
    Abstract: Compounds with unique liphagane meroterpenoid scaffold having boronic acid functionality in the skeleton are described (formula 1) together with pharmacological potential of these compounds as anticancer agents. A method of preparation and inhibiting the activity of phosphoinositide-3-kinase (PI3K-alpha and beta) has been presented. In particular, the invention describes a method of inhibiting PI3K isoforms, wherein the compounds are novel structures based on liphagane scaffold with unique boronic acid functionality. The methods and uses thereof are described herein this invention.
    Type: Grant
    Filed: March 18, 2013
    Date of Patent: December 8, 2015
    Assignee: Counsel of Scientific & Industrial Research
    Inventors: Ram Asrey Vishwakarma, Sanghapal Damodhar Sawant, Parvinder Pal Singh, Abid Hamid Dar, Parduman Raj Sharma, Ajit Kumar Saxena, Amit Nargotra, Anjaneya Aravind Kumar Kolluru, Ramesh Mudududdla, Asif Khurshid Qazi, Aashiq Hussain, Nayan Chanauria
  • 2-anilino nicotinyl linked 2-amino benzothiazole conjugates and process for the preparation thereof
    Patent number: 9029553
    Abstract: The present invention provides compounds of general formula A useful as potential anticancer agents against human cancer cell lines and apoptosis inducers. The present invention further provides a process for the preparation of 2-anilino nicotinyl linked 2-amino benzothiazole conjugates of general formula (A), wherein R1?H or Cl; R2?H, OCH3 or F; R3?H, OCH3, F or Cl; R4?H, OCH3 or F and X?OCH3, F or N02.
    Type: Grant
    Filed: March 30, 2011
    Date of Patent: May 12, 2015
    Assignee: Council of Scientific & Industrial Research
    Inventors: Ahmed Kamal, Yellamelli Valli Venkata Srikanth, Mohammed Naseer Ahmed Khan, Mohammed Ashraf, Irum Sehar, Gousia Chashoo, Parduman Raj Sharma, Abid Hamid Dar, Bhushan Shashi, Shashank Kumar Singh, Dilip Manikrao Mondhe, Ajit Kumar Saxena
  • BORONIC ACID BEARING LIPHAGANE COMPOUNDS AS INHIBITORS OF P13K- a AND/OR B
    Publication number: 20150051173
    Abstract: Compounds with unique liphagane meroterpenoid scaffold having boronic acid functionality in the skeleton are described (formula 1) together with pharmacological potential of these compounds as anticancer agents. A method of preparation and inhibiting the activity of phosphoinositide-3-kinase (PI3K-alpha and beta) has been presented. In particular, the invention describes a method of inhibiting PI3K isoforms, wherein the compounds are novel structures based on liphagane scaffold with unique boronic acid functionality. The methods and uses thereof are described herein this invention.
    Type: Application
    Filed: March 18, 2013
    Publication date: February 19, 2015
    Inventors: Ram Asrey Vishwakarma, Sanghapal Damodhar Sawant, Parvinder Pal Singh, Abid Hamid Dar, Parduman Raj Sharma, Ajit Kumar Saxena, Amit Nargotra, Anjaneya Aravind Kumar Kolluru, Ramesh Mudududdla, Asif Khurshid Qazi, Aashiq Hussain, Nayan Chanauria
  • 2-ANILINO NICOTINYL LINKED 2-AMINO BENZOTHIAZOLE CONJUGATES AND PROCESS FOR THE PREPARATION THEREOF
    Publication number: 20130324734
    Abstract: The present invention provides compounds of general formula A useful as potential anticancer agents against human cancer cell lines and apoptosis inducers. The present invention further provides a process for the preparation of 2-anilino nicotinyl linked 2-amino benzothiazole conjugates of general formula (A), wherein R1?H or CI; R2?H, OCH3 or F; R3?H, OCH3, F or CI; R4?H, OCH3 or F and X?OCH3, F or N02.
    Type: Application
    Filed: March 30, 2011
    Publication date: December 5, 2013
    Inventors: Ahmed Kamal, Yellamelli Valli Venkata Srikanth, Mohammed Naseer Ahmed Khan, Mohammed Ashraf, Irum Sehar, Gousia Chashoo, Parduman Raj Sharma, Abid Hamid Dar, Bhushan Shashi, Shashank Kumar Singh, Dilip Manikrao Mondhe, Ajit Kumar Saxena