Abstract: Methods of sterilizing medical devices, including implantable medical devices like stents, chemically and with radiation are disclosed. Methods of preparing a sterile, packaged medical device, including a sterile, packaged implantable medical device or stent are disclosed.

Abstract: A method of radiation sterilizing a plurality of stent-catheter assemblies includes positioning a plurality of stent-catheter assemblies on a fixture, each of the stent catheter assemblies being arranged in a planar configuration and disposed in corresponding planar packages supported on the fixture, wherein the packages are stacked horizontally on the fixture, and wherein the stents of the assemblies are positioned at a position in each package such that the stents are exposed to the same or substantially the same radiation; and exposing the packages to an incoming radiation beam, the radiation beam being at an acute angle to the planes of the planar configuration of the assemblies, wherein the packages are arranged such that a front end of the stack faces the radiation beam and a back end of the stack faces away from the radiation beam.

Abstract: Methods and systems for reduced temperature radiation sterilization of stents are disclosed.

Abstract: Disclosed herein is a method of radiation sterilizing a plurality of medical devices.

Abstract: A method and system of monitoring environmental exposure of stents using radiofrequency identification is disclosed.

Abstract: A method and system of monitoring environmental exposure of stents using radiofrequency identification is disclosed.

Abstract: Disclosed herein is a method of radiation sterilizing a plurality of medical devices.

Abstract: Methods of sterilizing medical devices, including implantable medical devices like stents, chemically and with radiation are disclosed. Methods of preparing a sterile, packaged medical device, including a sterile, packaged implantable medical device or stent are disclosed.

Abstract: A method and system of monitoring environmental exposure of stents using radiofrequency identification is disclosed.

Abstract: Methods and systems for reduced temperature radiation sterilization of stents are disclosed.

Abstract: Methods and systems for selection radiation exposure in sterilization of medical devices are disclosed.

Abstract: A device for sample collection, sample separation and for aseptically, controllably and precisely transferring at least one of the separated portions is disclosed. The device utilizes a metering syringe to collect a sample, such as blood, the metering syringe with the sample therein is centrifuged, the metering syringe is connected to a sterile syringe contained within sterile packaging, the metering syringe is used to controllably, precisely and aseptically meter a separated portion into the sterile syringe, the sterile syringe with the separated portion therein is then given to appropriate personnel within a sterile field without performing any further transferring steps.

Abstract: A fluid separation device and in-line orifice mixer system is disclosed. The fluid separation device utilizes a syringe, which is used for obtaining a fluid sample such as blood, in a centrifugation device, and further utilizes the syringe as a source of a separated fluid portion for storage and transfer for subsequent applications. The syringe containing the separated portion source and a second syringe containing a second source are connected to the in-line orifice mixer device. The mixer device comprises a plurality of orifice walls each providing an orifice non-aligned with adjacent orifices to homogeneously mix the plurality of components. The mixer device may further comprise an exit orifice wall with one or more orifices for discharge of the homogeneous mixture.

Abstract: The present invention discloses a novel method for preparing crosslinked biomaterial compositions for use in the augmentation of soft or hard tissue. In general, the method comprises mixing a biocompatible polymer, which is preferably collagen, with a sterile, dry crosslinking agent, which is preferably a synthetic hydrophilic polymer such as a functionally activated polyethylene glycol. Also provided are preferred processes for preparing sterile, dry crosslinking agents contained within syringes for use in the method of the invention. Methods for sterilization of the crosslinking agent include, but are not limited to, sterile filtration, aseptic processing, and e-beam or gamma irradiation. Methods for providing augmentation of soft or hard tissue using crosslinked biomaterial compositions prepared according to the method of the invention are also disclosed.