Abstract: Nutrient compositions for plant growth are disclosed. A nutrient composition includes primary macronutrients, including nitrogen, phosphorus, and potassium, secondary macronutrients including calcium and sulfur. A nutrient composition may include micronutrients and additional secondary macronutrients, such as magnesium. Nutrient compositions including such nutrient sources exhibit advantageous plant growth. Hydroponic nutrient composition, water soluble powder, and plant growth mediums containing the nutrient composition, as well as methods of using the nutrient compositions, are further disclosed.