Patents by Inventor Abigail YU

Abigail YU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250135025
    Abstract: The present disclosure relates to antibodies and antibody conjugates, for instance antibody drug conjugates, with binding specificity for receptor tyrosine kinase orphan receptor 1 (ROR1) and its isoforms and homologs, and compositions comprising the antibodies or antibody conjugates, including pharmaceutical compositions. Also provided are methods of producing the antibodies and antibody conjugates and compositions thereof as well as methods of using the antibodies and antibody conjugates and compositions thereof, such as in therapeutic and diagnostic methods.
    Type: Application
    Filed: December 30, 2024
    Publication date: May 1, 2025
    Inventors: Amandeep Gakhal, Abigail Yu, Ryan Stafford, Jeffrey Hanson, Alice Yam, Krishna Bajjuri, Andreas Maderna, Christina Abrahams, Xiaofan Li, Gang Yin, Miao Wen, Kristin Bedard, Daniel Calarese, Helena Kiefel
  • Patent number: 12226490
    Abstract: The present disclosure relates to antibodies and antibody conjugates, for instance antibody drug conjugates, with binding specificity for receptor tyrosine kinase orphan receptor 1 (ROR1) and its isoforms and homologs, and compositions comprising the antibodies or antibody conjugates, including pharmaceutical compositions. Also provided are methods of producing the antibodies and antibody conjugates and compositions thereof as well as methods of using the antibodies and antibody conjugates and compositions thereof, such as in therapeutic and diagnostic methods.
    Type: Grant
    Filed: July 10, 2023
    Date of Patent: February 18, 2025
    Assignee: Sutro Biopharma, Inc.
    Inventors: Amandeep Gakhal, Abigail Yu, Ryan Stafford, Jeffrey Hanson, Alice Yam, Krishna Bajjuri, Andreas Maderna, Cristina Abrahams, Xiaofan Li, Gang Yin, Miao Wen, Kristin Bedard, Daniel Calarese, Helena Kiefel
  • Publication number: 20250018054
    Abstract: The present disclosure relates to antibodies and antibody conjugates, for instance antibody drug conjugates, with binding specificity for receptor tyrosine kinase orphan receptor 1 (ROR1) and its isoforms and homologs, and compositions comprising the antibodies or antibody conjugates, including pharmaceutical compositions. Also provided are methods of producing the antibodies and antibody conjugates and compositions thereof as well as methods of using the antibodies and antibody conjugates and compositions thereof, such as in therapeutic and diagnostic methods.
    Type: Application
    Filed: September 4, 2024
    Publication date: January 16, 2025
    Inventors: Amandeep Gakhal, Abigail Yu, Ryan Stafford, Jeffrey Hanson, Alice Yam, Krishna Bajjuri, Andreas Maderna, Cristina Abrahams, Xiaofan Li, Gang Yin, Miao Wen, Kristin Bedard, Daniel Calarese, Helena Kiefel
  • Patent number: 12144869
    Abstract: The present disclosure relates to antibodies and antibody conjugates, for instance antibody drug conjugates, with binding specificity for receptor tyrosine kinase orphan receptor 1 (ROR1) and its isoforms and homologs, and compositions comprising the antibodies or antibody conjugates, including pharmaceutical compositions. Also provided are methods of producing the antibodies and antibody conjugates and compositions thereof as well as methods of using the antibodies and antibody conjugates and compositions thereof, such as in therapeutic and diagnostic methods.
    Type: Grant
    Filed: June 30, 2023
    Date of Patent: November 19, 2024
    Assignee: SUTRO BIOPHARMA, INC.
    Inventors: Amandeep Gakhal, Abigail Yu, Ryan Stafford, Jeffrey Hanson, Alice Yam, Krishna Bajjuri, Andreas Maderna, Cristina Abrahams, Xiaofan Li, Gang Yin, Miao Wen, Kristin Bedard, Daniel Calarese, Helena Kiefel
  • Publication number: 20240368295
    Abstract: The present disclosure relates to antibodies that selectively bind to B-cell maturation antigen (BCMA) and its isoforms and homologs, and compositions comprising the antibodies. Also provided are methods of using the antibodies, such as therapeutic and diagnostic methods.
    Type: Application
    Filed: April 17, 2024
    Publication date: November 7, 2024
    Inventors: Alice YAM, Ryan STAFFORD, Xiaofan LI, Junhao YANG, Stephanie ARMSTRONG, Abigail YU
  • Patent number: 11993658
    Abstract: The present disclosure relates to antibodies that selectively bind to B-cell maturation antigen (BCMA) and its isoforms and homologs, and compositions comprising the antibodies. Also provided are methods of using the antibodies, such as therapeutic and diagnostic methods.
    Type: Grant
    Filed: March 25, 2019
    Date of Patent: May 28, 2024
    Assignee: SUTRO BIOPHARMA, INC.
    Inventors: Alice Yam, Ryan Stafford, Xiaofan Li, Junhao Yang, Stephanie Armstrong, Abigail Yu
  • Publication number: 20240124585
    Abstract: The present disclosure relates to antibodies that selectively bind to CD3 and its isoforms and homologs, and compositions comprising the antibodies. Also provided are methods of using the antibodies, such as therapeutic and diagnostic methods.
    Type: Application
    Filed: September 29, 2023
    Publication date: April 18, 2024
    Inventors: Ryan STAFFORD, Junhao YANG, Alice YAM, Joni CASTRO, Gang YIN, Cuong TRAN, Xiaofan LI, Abigail YU
  • Publication number: 20240058465
    Abstract: The present disclosure relates to antibodies and antibody conjugates, for instance antibody drug conjugates, with binding specificity for receptor tyrosine kinase orphan receptor 1 (ROR1) and its isoforms and homologs, and compositions comprising the antibodies or antibody conjugates, including pharmaceutical compositions. Also provided are methods of producing the antibodies and antibody conjugates and compositions thereof as well as methods of using the antibodies and antibody conjugates and compositions thereof, such as in therapeutic and diagnostic methods.
    Type: Application
    Filed: June 30, 2023
    Publication date: February 22, 2024
    Inventors: Amandeep Gakhal, Abigail Yu, Ryan Stafford, Jeffrey Hanson, Alice Yam, Krishna Bajjuri, Andreas Maderna, Cristina Abrahams, Xiaofan Li, Gang Yin, Miao Wen, Kristin Bedard, Daniel Calarese, Helena Kiefel
  • Publication number: 20240058467
    Abstract: The present disclosure relates to antibodies and antibody conjugates, for instance antibody drug conjugates, with binding specificity for receptor tyrosine kinase orphan receptor 1 (ROR1) and its isoforms and homologs, and compositions comprising the antibodies or antibody conjugates, including pharmaceutical compositions. Also provided are methods of producing the antibodies and antibody conjugates and compositions thereof as well as methods of using the antibodies and antibody conjugates and compositions thereof, such as in therapeutic and diagnostic methods.
    Type: Application
    Filed: July 10, 2023
    Publication date: February 22, 2024
    Inventors: AMANDEEP GAKHAL, ABIGAIL YU, RYAN STAFFORD, JEFFREY HANSON, ALICE YAM, KRISHNA BAJJURI, ANDREAS MADERNA, CRISTINA ABRAHAMS, XIAOFAN LI, GANG YIN, MIAO WEN, KRISTIN BEDARD, DANIEL CALARESE, HELENA KIEFEL
  • Publication number: 20220362394
    Abstract: The present disclosure relates to antibody conjugates with binding specificity for BCMA (BCMA) and its isoforms and homologs, and compositions comprising the antibody conjugates, including pharmaceutical compositions. Also provided are methods of producing the antibody conjugates and compositions as well as methods of using the antibody conjugates and compositions, such as in therapeutic and diagnostic methods.
    Type: Application
    Filed: May 1, 2020
    Publication date: November 17, 2022
    Applicant: SUTRO BIOPHARMA, INC.
    Inventors: John LEE, Ryan STAFFORD, Alice YAM, Xiaofan LI, Abigail YU, Amandeep GAKHAL, Stephanie ARMSTRONG
  • Publication number: 20220323599
    Abstract: The present disclosure relates to antibody conjugates with binding specificity for BCMA (BCMA) and its isoforms and homologs, and compositions comprising the antibody conjugates, including pharmaceutical compositions. Also provided are methods of producing the antibody conjugates and compositions as well as methods of using the antibody conjugates and compositions, such as in therapeutic and diagnostic methods.
    Type: Application
    Filed: May 1, 2020
    Publication date: October 13, 2022
    Applicant: CELGENE CORPORATION
    Inventors: John LEE, Ryan STAFFORD, Alice YAM, Xiaofan LI, Abigail YU, Amandeep GAKHAL
  • Publication number: 20210130483
    Abstract: The present disclosure relates to antibodies that selectively bind to B-cell maturation antigen (BCMA) and its isoforms and homologs, and compositions comprising the antibodies. Also provided are methods of using the antibodies, such as therapeutic and diagnostic methods.
    Type: Application
    Filed: March 25, 2019
    Publication date: May 6, 2021
    Inventors: Alice YAM, Ryan STAFFORD, Xiaofan LI, Junhao YANG, Stephanie ARMSTRONG, Abigail YU