Abstract: A self-injury sleeve is provided. The presently-disclosed self-injury deterrent sleeves can comprise a sleeve body that is tubular and configured to receive an appendage. The sleeves can further include one or more self-injury deterrent pads provided on an outer side of the sleeve body that are comprised of a material having greater resistance to cutting and abrasion than the sleeve body material, a material that is softer than the sleeve body material, or a combination thereof. The sleeves can be worn by individuals to deter self-cutting and other self-injury.