Patents by Inventor Abraham Lin
Abraham Lin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20250369863Abstract: Provided is a method for determining a status of a sample comprising a co-culture comprising a target cellular object. TCO (520), and one or more stroma-forming cell types.Type: ApplicationFiled: June 29, 2023Publication date: December 4, 2025Applicant: Universiteit AntwerpenInventors: Maxim LE COMPTE, Christophe DEBEN, Edgar CARDENAS, Abraham LIN
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Patent number: 12329982Abstract: A method for treating a wart on skin of a patient includes guiding non-thermal, atmospheric pressure plasma over areas of the tissue having the wart for a length of time effective to give rise to an at least partial amelioration of the wart.Type: GrantFiled: October 13, 2023Date of Patent: June 17, 2025Assignee: Drexel UniversityInventors: Peter C. Friedman, Vandana Miller, Gregory Fridman, Abraham Lin, Alexander Fridman
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Publication number: 20240415562Abstract: Disclosed is a method for treating actinic keratosis of tissue of a patient, the method including contacting non-thermal, atmospheric pressure plasma over areas of the tissue having actinic keratosis for a time and at treatment conditions effective to give rise to an at least partial amelioration of the keratosis.Type: ApplicationFiled: June 20, 2024Publication date: December 19, 2024Inventors: Peter C. Friedman, Vandana Miller, Gregory Fridman, Abraham Lin, Alexander Fridman
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Patent number: 12042206Abstract: Disclosed is a method for treating actinic keratosis of tissue of a patient, the method including contacting non-thermal, atmospheric pressure plasma over areas of the tissue having actinic keratosis for a time and at treatment conditions effective to give rise to an at least partial amelioration of the keratosis.Type: GrantFiled: January 20, 2023Date of Patent: July 23, 2024Assignee: Drexel UniversityInventors: Peter C Friedman, Vandana Miller, Gregory Fridman, Abraham Lin, Alexander Fridman
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Publication number: 20240230626Abstract: Provided is a method for determining an effect of a potential active agent on a sample comprising a co-culture comprising a target cellular object, TCO, and one or more further cell types, FCT, wherein the TCO has been labelled with a flourescent live-cell marker having a first emission/excitation profile, and with a luminescent cell-death marker, and optionally the FCT has been labelled with a fluorescent live-cell marker having a second emission/excitation profile different from the first emission/excitation profile, comprising capturing, during an acquisition event using a microscope, a first fluorescent image from the fluorescent live-cell marker having the first emission/excitation profile, and optionally a second fluorescent image from the fluorescent live-cell marker having the second emission/excitation profile, and a luminescence measurement of the sample, and comparing fluorescent images and luminescent measurements between sample contacted with the potential active agent and sample not contacted wiType: ApplicationFiled: March 14, 2022Publication date: July 11, 2024Applicant: UNIVERSITEIT ANTWERPENInventors: Christophe DEBEN, Edgar CARDENAS, Maxim LE COMPTE, Abraham LIN
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Publication number: 20240189613Abstract: A method for treating a wart on skin of a patient includes guiding non-thermal, atmospheric pressure plasma over areas of the tissue having the wart for a length of time effective to give rise to an at least partial amelioration of the wart.Type: ApplicationFiled: October 13, 2023Publication date: June 13, 2024Inventors: Peter C. Friedman, Vandana Miller, Gregory Fridman, Abraham Lin, Alexander Fridman
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Publication number: 20240133869Abstract: Provided is a method for determining an effect of a potential active agent on a sample comprising a co-culture comprising a target cellular object, TCO, and one or more further cell types, FCT, wherein the TCO has been labelled with a flourescent live-cell marker having a first emission/excitation profile, and with a luminescent cell-death marker, and optionally the FCT has been labelled with a fluorescent live-cell marker having a second emission/excitation profile different from the first emission/excitation profile, comprising capturing, during an acquisition event using a microscope, a first fluorescent image from the fluorescent live-cell marker having the first emission/excitation profile, and optionally a second fluorescent image from the fluorescent live-cell marker having the second emission/excitation profile, and a luminescence measurement of the sample, and comparing fluorescent images and luminescent measurements between sample contacted with the potential active agent and sample not contacted wiType: ApplicationFiled: March 13, 2022Publication date: April 25, 2024Applicant: UNIVERSITEIT ANTWERPENInventors: Christophe DEBEN, Edgar CARDENAS, Maxim LE COMPTE, Abraham LIN
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Publication number: 20230371998Abstract: Disclosed is a method for treating actinic keratosis of tissue of a patient, the method including contacting non-thermal, atmospheric pressure plasma over areas of the tissue having actinic keratosis for a time and at treatment conditions effective to give rise to an at least partial amelioration of the keratosis.Type: ApplicationFiled: January 20, 2023Publication date: November 23, 2023Inventors: Peter C. Friedman, Vandana Miller, Gregory Fridman, Abraham Lin, Alexander Fridman
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Patent number: 11571249Abstract: Disclosed is a method for treating actinic keratosis of tissue of a patient, the method including contacting non-thermal, atmospheric pressure plasma over areas of the tissue having actinic keratosis for a time and at treatment conditions effective to give rise to an at least partial amelioration of the keratosis.Type: GrantFiled: August 1, 2017Date of Patent: February 7, 2023Assignee: Drexel UniversityInventors: Peter C. Friedman, Vandana Miller, Gregory Fridman, Abraham Lin, Alexander Fridman
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Publication number: 20220256682Abstract: Applications of dielectric barrier discharge (DBD) based atmospheric pressure plasma jets are often limited by the relatively small area of treatment due to their 1D configuration. This system generates 2D plasma jets permitting fast treatment of larger targets. DBD evolution starts with formation of transient anode glow, and continues with development of cathode-directed streamers. The anode glow can propagate as an ionization wave along the dielectric surface through and outside of the discharge gap. Plasma propagation is not limited to 1D geometry such as tubes, and can be organized in a form of a rectangular plasma jet, or other 2D or 3D shapes. Also described are a method for generating 2D plasma jets and use of the 2D plasma jets for cancer therapy.Type: ApplicationFiled: January 3, 2022Publication date: August 11, 2022Applicants: Drexel University, Thomas Jefferson UniversityInventors: Danil V. DOBRYNIN, Alexander FRIDMAN, Abraham LIN, Vandana MILLER, Adam Snook
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Patent number: 11219118Abstract: Applications of dielectric barrier discharge (DBD) based atmospheric pressure plasma jets are often limited by the relatively small area of treatment due to their 1D configuration. This system generates 2D plasma jets permitting fast treatment of larger targets. DBD evolution starts with formation of transient anode glow, and continues with development of cathode-directed streamers. The anode glow can propagate as an ionization wave along the dielectric surface through and outside of the discharge gap. Plasma propagation is not limited to 1D geometry such as tubes, and can be organized in a form of a rectangular plasma jet, or other 2D or 3D shapes. Also described are a method for generating 2D plasma jets and use of the 2D plasma jets for cancer therapy.Type: GrantFiled: February 20, 2019Date of Patent: January 4, 2022Assignees: Drexel University, Thomas Jefferson UniversityInventors: Danil V. Dobrynin, Alexander Fridman, Abraham Lin, Vandana Miller, Adam Snook
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Publication number: 20210282831Abstract: Disclosed is a method for treating actinic keratosis of tissue of a patient, the method including contacting non-thermal, atmospheric pressure plasma over areas of the tissue having actinic keratosis for a time and at treatment conditions effective to give rise to an at least partial amelioration of the keratosis.Type: ApplicationFiled: August 1, 2017Publication date: September 16, 2021Inventors: Peter C. FRIEDMAN, Vandana MILLER, Gregory FRIDMAN, Abraham LIN, Alexander FRIDMAN
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Publication number: 20210260395Abstract: A method for treating a wart on skin of a patient includes guiding non-thermal, atmospheric pressure plasma over areas of the tissue having the wart for a length of time effective to give rise to an at least partial amelioration of the wart.Type: ApplicationFiled: June 26, 2019Publication date: August 26, 2021Applicant: DREXEL UNIVERSITYInventors: Peter C. Friedman, Vandana Miller, Gregory Fridman, Abraham Lin, Alexander Fridman
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Publication number: 20210029813Abstract: Applications of dielectric barrier discharge (DBD) based atmospheric pressure plasma jets are often limited by the relatively small area of treatment due to their 1D configuration. This system generates 2D plasma jets permitting fast treatment of larger targets. DBD evolution starts with formation of transient anode glow, and continues with development of cathode-directed streamers. The anode glow can propagate as an ionization wave along the dielectric surface through and outside of the discharge gap. Plasma propagation is not limited to 1D geometry such as tubes, and can be organized in a form of a rectangular plasma jet, or other 2D or 3D shapes. Also described are a method for generating 2D plasma jets and use of the 2D plasma jets for cancer therapy.Type: ApplicationFiled: February 20, 2019Publication date: January 28, 2021Applicants: Drexel University, Thomas Jefferson UniversityInventors: Danil V. DOBRYNIN, Alexander FRIDMAN, Abraham LIN, Vandana MILLER, Adam Snook
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Publication number: 20160129156Abstract: Methods and apparatus of providing a joint replacement parts with a pharmaceutical delivery system is provided. The pharmaceutical delivery system is placed within the joint replacement parts to provide, over a period of time, sustained release of a controlled concentration of pharmaceuticals within the joint space of the joint replacement and to produce a local or systemic physiological of pharmacological effect.Type: ApplicationFiled: November 8, 2014Publication date: May 12, 2016Inventors: Abraham Lin, Steve Li
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Publication number: 20150051539Abstract: Methods and apparatus of providing a joint replacement parts with a pharmaceutical delivery system is provided. The pharmaceutical delivery system is placed within the joint replacement parts to provide, over a period of time, sustained release of a controlled concentration of pharmaceuticals within the joint space of the joint replacement and to produce a local or systemic physiological of pharmacological effect.Type: ApplicationFiled: August 13, 2013Publication date: February 19, 2015Inventor: Abraham Lin
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Patent number: 8911500Abstract: Methods and apparatus of providing a joint replacement parts with a pharmaceutical delivery system is provided. The pharmaceutical delivery system is placed within the joint replacement parts to provide, over a period of time, sustained release of a controlled concentration of pharmaceuticals within the joint space of the joint replacement and to produce a local or systemic physiological of pharmacological effect.Type: GrantFiled: March 15, 2013Date of Patent: December 16, 2014Inventor: Abraham Lin
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Publication number: 20140277515Abstract: Methods and apparatus of providing a joint replacement parts with a pharmaceutical delivery system is provided. The pharmaceutical delivery system is placed within the joint replacement parts to provide, over a period of time, sustained release of a controlled concentration of pharmaceuticals within the joint space of the joint replacement and to produce a local or systemic physiological of pharmacological effect.Type: ApplicationFiled: March 15, 2013Publication date: September 18, 2014Inventor: Abraham Lin
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Patent number: 8685106Abstract: Methods and apparatus of providing a joint replacement parts with a pharmaceutical delivery system is provided. The pharmaceutical delivery system is placed within the joint replacement parts to provide, over a period of time, sustained release of a controlled concentration of pharmaceuticals within the joint space of the joint replacement and to produce a local or systemic physiological of pharmacological effect.Type: GrantFiled: March 1, 2012Date of Patent: April 1, 2014Inventors: Abraham Lin, Jiunyih Li
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Publication number: 20130123742Abstract: Methods and apparatus of providing a joint replacement parts with a pharmaceutical delivery system is provided. The pharmaceutical delivery system is placed within the joint replacement parts to provide, over a period of time, sustained release of a controlled concentration of pharmaceuticals within the joint space of the joint replacement and to produce a local or systemic physiological of pharmacological effect.Type: ApplicationFiled: March 1, 2012Publication date: May 16, 2013Inventors: Abraham Lin, Jiunyih Li