Patents by Inventor Abraham Meir Rosenbaum

Abraham Meir Rosenbaum has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nanogrid Rolling Circle DNA Sequencing
    Publication number: 20170183726
    Abstract: The present invention relates to methods for sequencing a polynucleotide immobilized on an array having a plurality of specific regions each having a defined diameter size, including synthesizing a concatemer of a polynucleotide by rolling circle amplification, wherein the concatemer has a cross-sectional diameter greater than the diameter of a specific region, immobilizing the concatemer to the specific region to make an immobilized concatemer, and sequencing the immobilized concatemer.
    Type: Application
    Filed: March 8, 2017
    Publication date: June 29, 2017
    Inventors: George M. Church, Gregory J. Porreca, Jay Shendure, Abraham Meir Rosenbaum
  • Nanogrid rolling circle DNA sequencing
    Patent number: 9624538
    Abstract: The present invention relates to methods for sequencing a polynucleotide immobilized on an array having a plurality of specific regions each having a defined diameter size, including synthesizing a concatemer of a polynucleotide by rolling circle amplification, wherein the concatemer has a cross-sectional diameter greater than the diameter of a specific region, immobilizing the concatemer to the specific region to make an immobilized concatemer, and sequencing the immobilized concatemer.
    Type: Grant
    Filed: May 14, 2008
    Date of Patent: April 18, 2017
    Assignee: President and Fellows of Harvard College
    Inventors: George M. Church, Gregory J. Porreca, Jay Shendure, Abraham Meir Rosenbaum
  • NANOGRID ROLLING CIRCLE DNA SEQUENCING
    Publication number: 20090018024
    Abstract: The present invention relates to methods for sequencing a polynucleotide immobilized on an array having a plurality of specific regions each having a defined diameter size, including synthesizing a concatemer of a polynucleotide by rolling circle amplification, wherein the concatemer has a cross-sectional diameter greater than the diameter of a specific region, immobilizing the concatemer to the specific region to make an immobilized concatemer, and sequencing the immobilized concatemer.
    Type: Application
    Filed: May 14, 2008
    Publication date: January 15, 2009
    Applicant: President and Fellows of Harvard College
    Inventors: George M. CHURCH, Gregory J. Porreca, Jay Shendure, Abraham Meir Rosenbaum