Patents by Inventor Abraham Spector

Abraham Spector has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of heme-peptides to prevent or retard disease associated with oxidative stress
    Patent number: 6013623
    Abstract: This invention provides a method for treating a condition associated with oxidative stress in a subject which comprises administering to the subject an amount of a heme-peptide effective to treat the condition associated with oxidative stress in the subject. The subject may be a mammal. The mammal may be a human being. The condition associated with oxidative stress may be an inflammatory condition, an allergic condition or an auto-immune condition.
    Type: Grant
    Filed: February 27, 1997
    Date of Patent: January 11, 2000
    Assignee: The Trustees of Columbia University in the City of New York
    Inventors: Abraham Spector, Wanchao Ma, Ren-Rong Wang
  • Compounds having glutathione peroxidase activity and use thereof
    Patent number: 5321138
    Abstract: The present invention provides compounds having glutathione peroxidase activity and, therefore, are effective glutathione peroxidase replacements. These compounds are useful as drugs for the prevention of cataracts and as anti-oxidants for H.sub.2 O.sub.2 and other peroxides. The present invention also provides methods and pharmaceutical compositions of the compound.
    Type: Grant
    Filed: April 29, 1991
    Date of Patent: June 14, 1994
    Assignees: The Trustees of Columbia University in the City of New York, New York University
    Inventors: Abraham Spector, Stephen R. Wilson, Paul A. Zucker
  • Compounds having glutathione peroxidase activity and use thereof
    Patent number: 5128365
    Abstract: The present invention provides compounds having glutathione peroxidase activity and, therefore, are effective glutathione peroxidase replacements. These compounds are useful as drugs for the prevention of cataracts and as anti-oxidants for H.sub.2 O.sub.2 and other peroxides. The present invention also provides methods and pharmaceutical compositions of the compound.
    Type: Grant
    Filed: July 19, 1989
    Date of Patent: July 7, 1992
    Assignees: The Trustees of Columbia University in the City of New York, New York University
    Inventors: Abraham Spector, Stephen R. Wilson, Paul A. Zucker
  • Method and ophthalmic composition for the prevention and reversal of cataracts
    Patent number: 4771036
    Abstract: The subject invention concerns a process for the prevention and reversal of cataracts. Specifically, the invention comprises the treatment of the eye lens with an effective cataract inhibiting amount of thioredoxin or thioredoxin-derived, or thioredoxin-like, dithiol peptide, alone, or in combination with a thioredoxin reductase regenerating system. The thioredoxin compound can be administered topically to a patient in need of such treatment on a daily basis over an extended period of time via known delivery techniques such as eye drops and ocular inserts.
    Type: Grant
    Filed: February 10, 1986
    Date of Patent: September 13, 1988
    Assignee: Trustees of Columbia University in the city of New York
    Inventors: Vincent P. Pigiet, Abraham Spector