Patents by Inventor Abram Becker

Abram Becker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20160152979
    Abstract: Disclosed herein are novel compounds having the general formula (I): Q-L-A1??(I) wherein Q is a Q10 moiety, such as ubiquinone; L, which is optionally included, is a linker selected from the group consisting of polyesters, polyethers, polyamines, polyamides, peptides, carbohydrates, lipids, C3-12 alkyl straight chain based linkers, polyethylene glycols and other polymeric compounds; and A1 is a nucleotide moiety. Disclosed are also pharmaceutical compositions comprising such compounds or pharmaceutically acceptable salts thereof. Further disclosed is the use of such compounds in the treatment of cancer and/or a cancer related medical condition.
    Type: Application
    Filed: February 3, 2016
    Publication date: June 2, 2016
    Applicants: QBI ENTERPRISES LTD., BIO-LAB LTD.
    Inventors: Sharon AVKIN-NACHUM, Abram BECKER, Tirtsa KLEINMAN, Myriam LEFOIX, Jean-Christophe TRUFFERT
  • Patent number: 7619116
    Abstract: A subject matter of the present invention is novel intermediates for the synthesis of (R)-tamsulosin and of its pharmaceutically acceptable salts, and also the associated preparation process.
    Type: Grant
    Filed: December 15, 2004
    Date of Patent: November 17, 2009
    Assignee: Products Chimiques Auxiliaires Et de Synthese
    Inventors: Valéry Dambrin, Jean-Yves Lenoir, Jean-Marie Schneider, Gérard Guillamot, Michel Follet, Abram Becker
  • Publication number: 20070106079
    Abstract: A subject matter of the present invention is novel intermediates for the synthesis of (R)-tamsulosin and of its pharmaceutically acceptable salts, and also the associated preparation process.
    Type: Application
    Filed: December 15, 2004
    Publication date: May 10, 2007
    Inventors: Valéry Dambrin, Jean-Yves Lenoir, Jean-Marie Schneider, Gerard Guillamot, Michel Follet, Abram Becker
  • Patent number: 5294416
    Abstract: In a process for the preparation and the isolation of p-hydroxybenzonitrile (HBN), in which a p-halogenated phenol is reacted with cuprous cyanide in a suitable solvent, the reaction mixture obtained after the reaction of the p-halogenated phenol with cuprous cyanide has been substantially completed is contacted with an aqueous solution of a bromide salt and, optionally, an organic diluent, the aqueous and organic phases are separated, HBN is distilled out from the organic phase, an alkali metal cyanide is added to the aqueous phase and CuCN is filtered off from the resulting aqueous phase.
    Type: Grant
    Filed: September 11, 1992
    Date of Patent: March 15, 1994
    Assignee: Bromine Compounds Limited
    Inventors: Abram Becker, Hyman Stollar
  • Patent number: 5177258
    Abstract: Biaryl derivatives are produced by coupling an aryl halide in an aqueous alkaline solution in the presence of a palladium catalyst, using formic hydrazide as the reducing agent.
    Type: Grant
    Filed: May 21, 1992
    Date of Patent: January 5, 1993
    Assignee: Bromine Compounds, Ltd.
    Inventors: Abram Becker, Ariel A. Ewenson, Bertha Croitoru
  • Patent number: 5169972
    Abstract: In a process for the preparation and the isolation of p-hydroxybenzonitrile (HBN), in which a p-halogenated phenol is reacted with cuprous cyanide in a suitable solvent, the reaction mixture obtained after the reaction of the p-halogenated phenol with cuprous cyanide has been substantially completed is contacted with an aqueous solution of a bromide salt and, optionally, an organic diluent, the aqueous and organic phases are separated, HBN is distilled out from the organic phase, an alkali metal cyanide is added to the aqueous phase and CuCN is filtered off from the resulting aqueous phase.
    Type: Grant
    Filed: December 3, 1990
    Date of Patent: December 8, 1992
    Assignee: Bromine Compounds Limited
    Inventors: Abram Becker, Hyman Stollar
  • Patent number: 4925642
    Abstract: A process is provided by means of which aromatic nitriles can be isolated in high yield. The process comprises reacting an aromatic halogenated compound with cuprous cyanide in a suitable solvent.The process is suitable for preparing many important materials, such as p-hydroxybenzonitrile.
    Type: Grant
    Filed: May 24, 1988
    Date of Patent: May 15, 1990
    Assignee: Bromine Compounds Limited
    Inventors: Hayman Stollar, Abram Becker
  • Patent number: 4898993
    Abstract: A process is described which permits to prepare substantially pure 2-tert-butyl-4-methoxyphenol, by reacting 4-bromo-2-tert-butylphenol with a methoxide in an organic solvent.The process permits to obtain a substantially pure 2-isomer, and avoids the need for the separation of the 2- and 3-isomers.
    Type: Grant
    Filed: January 13, 1988
    Date of Patent: February 6, 1990
    Assignee: Bromine Compounds Limited
    Inventors: Abram Becker, Nurit Kornberg, Berta Croitoru
  • Patent number: 4789743
    Abstract: The invention relates to a process for the preparaton of compounds of the formula I by reacting an alkali metal alcoholate with a compound of the formula II in the presence of an aliphatic ester such as methyl formate, and then condensing guanidine with the resulting compound of the formula III.The compound of the formula II can be prepared by reacting the corresponding benzaldehyde with acrylonitrile in the presence of diazabicyclo-2,2,2,-octane.
    Type: Grant
    Filed: July 31, 1987
    Date of Patent: December 6, 1988
    Assignee: Societe Anonyme: Sanofi Pharma S.A. - Succursale de Carouge
    Inventor: Abram Becker