Patents by Inventor ABUBAKAR WANI

ABUBAKAR WANI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Alkylidene phosphonate esters as p-glycoprotein inducers
    Patent number: 10377781
    Abstract: The present invention relates to the alkylidene phosphonate esters of formula I wherein, R1 is selected from a group consisting of hydrogen or alkyl group; R2 is selected from a group consisting of hydrogen, hydroxy, alkyl, alkoxy, nitro, halogen, amino, N-substituted alkylamino; alkyl group is selected from a group consisting of methyl, ethyl and isopropyl; Ar is selected from a group consisting of aryl, substituted aryl, fused aryl, heteroaryl, and substituted heteroaryl. The present invention particularly relates to synthesis and p-glycoprotein induction activity of the alkylidene phosphonate esters. In addition, the invention relates to methods of using compounds for treating or preventing Alzheimer's disease.
    Type: Grant
    Filed: September 16, 2015
    Date of Patent: August 13, 2019
    Assignee: COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH
    Inventors: Sandip Bharate, Ajay Kumar, Sudhakar Manda, Prashant Joshi, Sonali Bharate, Abubakar Wani, Sadhana Sharma, Ram Vishwakarma
  • Polyprenylated phloroglucinol compounds as potent P-glycoprotein inducers
    Patent number: 10202326
    Abstract: The present invention relates to the polyprenylated phloroglucinol compounds of formulae I and II. The present invention also provides synthesis and p-glycoprotein induction activity of the alkyl- and acyl-polyprenylated phloroglucinol compounds. Further, use of the compounds as p-glycoprotein inducers and methods of treatment of Alzheimer's disease using compounds of the invention are also provided.
    Type: Grant
    Filed: July 20, 2015
    Date of Patent: February 12, 2019
    Assignee: COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH
    Inventors: Sandip Bharate, Ajay Kumar, Jaideep Bharate, Prashant Joshi, Abubakar Wani, Ramesh Mudududdla, Rohit Sharma, Ram Vishwakarma
  • POLYPRENYLATED PHLOROGLUCINOL COMPOUNDS AS POTENT P-GLYCOPROTEIN INDUCERS
    Publication number: 20170320802
    Abstract: The present invention relates to the polyprenylated phloroglucinol compounds of formulae I and II. The present invention also provides synthesis and p-glycoprotein induction activity of the alkyl- and acyl-polyprenylated phloroglucinol compounds. Further, use of the compounds as p-glycoprotein inducers and methods of treatment of Alzheimer's disease using compounds of the invention are also provided.
    Type: Application
    Filed: July 20, 2015
    Publication date: November 9, 2017
    Applicant: COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH
    Inventors: Sandip BHARATE, Ajay KUMAR, Jaideep BHARATE, Prashant JOSHI, Abubakar WANI, Ramesh MUDUDUDDLA, Rohit SHARMA, Ram VISHWAKARMA
  • ALKYLIDENE PHOSPHONATE ESTERS AS P-GLYCOPROTEIN INDUCERS
    Publication number: 20170275314
    Abstract: The present invention relates to the alkylidene phosphonate esters of formula I wherein, R1 is selected from a group consisting of hydrogen or alkyl group; R2 is selected from a group consisting of hydrogen, hydroxy, alkyl, alkoxy, nitro, halogen, amino, N-substituted alkylamino; alkyl group is selected from a group consisting of methyl, ethyl and isopropyl; Ar is selected from a group consisting of aryl, substituted aryl, fused aryl, heteroaryl, and substituted heteroaryl. The present invention particularly relates to synthesis and p-glycoprotein induction activity of the alkylidene phosphonate esters. In addition, the invention relates to methods of using compounds for treating or preventing Alzheimer's disease.
    Type: Application
    Filed: September 16, 2015
    Publication date: September 28, 2017
    Inventors: SANDIP BHARATE, AJAY KUMAR, SUDHAKAR MANDA, PRASHANT JOSHI, SONALI BHARATE, ABUBAKAR WANI, SADHANA SHARMA, RAM VISHWAKARMA