Patents by Inventor Abujiang Pataer

Abujiang Pataer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods involving MDA-7 for the treatment of cancer
    Publication number: 20070009484
    Abstract: The present invention concerns methods and compositions involving MDA-7 protein or an MDA-7-encoding nucleic acid in combination with either 1) a COX-2 selective inhibitor, such as celecoxib, 2) an Hsp90 inhibitor, such as geldanamycin, or a geldanamycin derivative or analog, 3) a vitamin E compound, for the treatment of cancer, 4) a TNF, such as TNF-alpha, 5) a VEGF inhibitor, or 6) an inhibitor of IL-10. In certain examples, a treatment for breast cancer is provided. In other examples a treatment for lung cancer is provided. Such examples involve, in some cases, an adenovirus vector that expresses MDA-7 protein.
    Type: Application
    Filed: February 8, 2006
    Publication date: January 11, 2007
    Inventors: Kelly Hunt, Young-Jin Suh, Stephen Swisher, Abujiang Pataer, Rajagopal Ramesh, Manish Shanker
  • Methods of enhancing immune induction involving MDA-7
    Publication number: 20040009939
    Abstract: The present invention relates to compositions and methods for the enhancing or inducing an immune response against an immunogenic molecule by indirectly activating PKR. More specifically, immunotherapy is improved by co-administering a MDA-7 polypeptide with an immunogenic molecule against which an immune response is desired. Such immunotherapies include cancer vaccines, and compositions thereof are described.
    Type: Application
    Filed: March 3, 2003
    Publication date: January 15, 2004
    Applicants: Board of Regent, The University of Texas System, Introgen Therapeutics, Inc.
    Inventors: Sunil Chada, Abujiang Pataer, Abner Mhashilkar, Rajagopal Ramesh, Jack Roth, Steve Swisher