Patents by Inventor Abul AZIM

Abul AZIM has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for preparing Alectinib or a pharmaceutically acceptable salt thereof
    Patent number: 11465999
    Abstract: The present invention relates to a process for preparing the Alectinib or a pharmaceutically acceptable salt thereof using lesser reaction steps and also eliminating expensive and time-consuming column chromatography. The invention also relates to novel polymorphic forms of Alectinib and Alectinib hydrochloride.
    Type: Grant
    Filed: August 16, 2021
    Date of Patent: October 11, 2022
    Assignee: FRESENIUS KABI ONCOLOGY LTD.
    Inventors: Vinod Singh Tomar, Abul Azim, Nitin Gupta, Saswata Lahiri, Walter Cabri
  • Polymorphic forms of Afatinib free base and Afatinib dimaleate
    Patent number: 11390612
    Abstract: The present invention relates to crystalline forms of Afatinib and its dimaleate salt. The present invention also relates to processes for the preparation of crystalline forms of Afatinib and its dimaleate salt. The present invention further relates to pharmaceutical compositions of such crystalline forms of Afatinib dimaleate and use thereof in the treatment of a patient in need thereof.
    Type: Grant
    Filed: October 1, 2020
    Date of Patent: July 19, 2022
    Assignee: Fresenius Kabi Oncology Ltd.
    Inventors: Walter Cabri, Saswata Lahiri, Bhuwan Bhaskar Mishra, Abul Azim, Nilendu Panda, Poli Reddy Bhavanam, Krishanu Ray, Nikunj Kachhadia, Kumber Singh
  • PROCESS FOR PREPARING ALECTINIB OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF
    Publication number: 20210371410
    Abstract: The present invention relates to a process for preparing the Alectinib or a pharmaceutically acceptable salt thereof using lesser reaction steps and also eliminating expensive and time-consuming column chromatography. The invention also relates to novel polymorphic forms of Alectinib and Alectinib hydrochloride.
    Type: Application
    Filed: August 16, 2021
    Publication date: December 2, 2021
    Applicant: FRESENIUS KABI ONCOLOGY LIMITED
    Inventors: Vinod Singh TOMAR, Abul AZIM, Nitin GUPTA, Saswata LAHIRI, Walter CABRI
  • Process for preparing alectinib or a pharmaceutically acceptable salt thereof
    Patent number: 11098037
    Abstract: The present invention relates to a process for preparing the Alectinib or a pharmaceutically acceptable salt thereof using lesser reaction steps and also eliminating expensive and time-consuming column chromatography. The invention also relates to novel polymorphic forms of Alectinib and Alectinib hydrochloride.
    Type: Grant
    Filed: July 4, 2018
    Date of Patent: August 24, 2021
    Assignee: Fresenius Kabi Oncology Ltd.
    Inventors: Vinod Singh Tomar, Abul Azim, Nitin Gupta, Saswata Lahiri, Walter Cabri
  • POLYMORPHIC FORMS OF AFATINIB FREE BASE AND AFATINIB DIMALEATE
    Publication number: 20210024506
    Abstract: The present invention relates to crystalline forms of Afatinib and its dimaleate salt. The present invention also relates to processes for the preparation of crystalline forms of Afatinib and its dimaleate salt. The present invention further relates to pharmaceutical compositions of such crystalline forms of Afatinib dimaleate and use thereof in the treatment of a patient in need thereof.
    Type: Application
    Filed: October 1, 2020
    Publication date: January 28, 2021
    Applicant: FRESENIUS KABI ONCOLOGY LIMITED
    Inventors: Walter CABRI, Saswata LAHIRI, Bhuwan Bhaskar MISHRA, Abul AZIM, Nilendu PANDA, Poli Reddy BHAVANAM, Krishanu RAY, Nikunj KACHHADIA, Kumber SINGH
  • Polymorphic forms of Afatinib free base and Afatinib dimaleate
    Patent number: 10800763
    Abstract: The present invention relates to crystalline forms of Afatinib and its dimaleate salt. The present invention also relates to processes for the preparation of crystalline forms of Afatinib and its dimaleate salt. The present invention further relates to pharmaceutical compositions of such crystalline forms of Afatinib dimaleate and use thereof in the treatment of a patient in need thereof.
    Type: Grant
    Filed: June 10, 2016
    Date of Patent: October 13, 2020
    Assignee: Fresenius Kabi Oncology Ltd.
    Inventors: Walter Cabri, Saswata Lahiri, Bhuwan Bhaskar Mishra, Abul Azim, Nilendu Panda, Poli Reddy Bhavanam, Krishanu Ray, Nikunj Kachhadia, Kumber Singh
  • A PROCESS FOR PREPARING ALECTINIB OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF
    Publication number: 20200140427
    Abstract: The present invention relates to a process for preparing the Alectinib or a pharmaceutically acceptable salt thereof using lesser reaction steps and also eliminating expensive and time-consuming column chromatography. The invention also relates to novel polymorphic forms of Alectinib and Alectinib hydrochloride.
    Type: Application
    Filed: July 4, 2018
    Publication date: May 7, 2020
    Applicant: FRESENIUS KABI ONCOLOGY LIMITED
    Inventors: Vinod Singh TOMAR, Abul AZIM, Nitin GUPTA, Saswata LAHIRI, Walter CABRI
  • POLYMORPHIC FORMS OF AFATINIB FREE BASE AND AFATINIB DIMALEATE
    Publication number: 20180312494
    Abstract: The present invention relates to crystalline forms of Afatinib and its dimaleate salt. The present invention also relates to processes for the preparation of crystalline forms of Afatinib and its dimaleate salt. The present invention further relates to pharmaceutical compositions of such crystalline forms of Afatinib dimaleate and use thereof in the treatment of a patient in need thereof.
    Type: Application
    Filed: June 10, 2016
    Publication date: November 1, 2018
    Applicant: FRESENIUS KABI ONCOLOGY LTD.
    Inventors: Walter CABRI, Saswata LAHIRI, Bhuwan Bhaskar MISHRA, Abul AZIM, Nilendu PANDA, Poli Reddy BHAVANAM, Krishanu RAY, Nikunj KACHHADIA, Kumber SINGH
  • Process for the preparation of cabazitaxel
    Patent number: 9000193
    Abstract: The present invention discloses a process for the preparation of 4-acetoxy-2?-benzoyloxy-5?,20-epoxy-1-hydroxy-7?,10?-dimethoxy-9-oxotax-11-en-13?-yl(2R,3S)-3-tert-butoxycarbonylamino-2-hydroxy-3-phenyl-propionate Cabazitaxel (I).
    Type: Grant
    Filed: November 5, 2014
    Date of Patent: April 7, 2015
    Assignee: Fresenius Kabi Oncology Limited
    Inventors: Saswata Lahiri, Nitin Gupta, Abul Azim, Nilendu Panda, Bhuwan Bhaskar Mishra, Sunil Sanghani
  • PROCESS FOR THE PREPARATION OF CABAZITAXEL
    Publication number: 20150057454
    Abstract: The present invention discloses a process for the preparation of 4-acetoxy-2?-benzoyloxy-5?,20-epoxy-1-hydroxy-7?,10?-dimethoxy-9-oxotax-11-en-13?-yl(2 R,35)-3-tert-butoxycarbonylamino-2-hydroxy-3-phenyl-propionate Cabazitaxel (I).
    Type: Application
    Filed: November 5, 2014
    Publication date: February 26, 2015
    Inventors: Saswata Lahiri, Nitin Gupta, Abul Azim, Nilendu Panda, Bhuwan Bhaskar Mishra, Sunil Sanghani
  • Process for the preparation cabazitaxel
    Patent number: 8901327
    Abstract: The present invention discloses a process for the preparation of 4-acetoxy-2?-benzoyloxy-5?,20-epoxy-1-hydroxy-7?,10?-dimethoxy-9-oxotax-11-en-13?-yl(2R,3S)-3-tert-butoxycarbonylamino-2-hydroxy-3-phenyl-propionate Cabazitaxel (I).
    Type: Grant
    Filed: September 24, 2012
    Date of Patent: December 2, 2014
    Assignee: Fresenius Kabi Oncology Limited
    Inventors: Saswata Lahiri, Nitin Gupta, Abul Azim, Nilendu Panda, Bhuwan Bhaskar Mishra, Sunil Sanghani
  • PROCESS FOR THE PREPARATION CABAZITAXEL
    Publication number: 20140058119
    Abstract: The present invention discloses a process for the preparation of 4-acetoxy-2?-benzoyloxy-5?,20-epoxy-1-hydroxy-7?,10?-dimethoxy-9-oxotax-11-en-13?-yl(2R,3S)-3-tert-butoxycarbonylamino-2-hydroxy-3-phenyl-propionate Cabazitaxel (I).
    Type: Application
    Filed: September 24, 2012
    Publication date: February 27, 2014
    Applicant: FRESENIUS KABI ONCOLOGY LIMITED
    Inventors: Saswata LAHIRI, Nitin GUPTA, Abul AZIM, Nilendu PANDA, Bhuwan Bhaskar MISHRA, Sunil SANGHANI