Patents by Inventor Achim Schwammle

Achim Schwammle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7407812
    Abstract: The invention relates to a method and a kit for the isolation of phosphorylated peptides from complex mixtures using support materials having chelate ligands based on silica and alkaline elution buffers. In preferred embodiments, the method according to the invention enables the isolation of phosphopeptides from complex sample solutions with a reproducibly high yield and at the same time with high purity and it allows efficient ionisation and detection of the isolated phosphopeptides both by MALDI-TOF and also by ESI mass spectrometry without additional requisite method steps, such as, for example, chromatographic desalination of the sample.
    Type: Grant
    Filed: April 21, 2005
    Date of Patent: August 5, 2008
    Assignee: Merck Patent GmbH
    Inventors: Jonas Anders, Achim Schwämmle, Sven Andrecht, Robertus Hendriks, Anette Boerner, Cora Rueter
  • Publication number: 20070227974
    Abstract: The invention relates to a method and a kit for the isolation of phosphorylated peptides from complex mixtures using support materials having chelate ligands based on silica and alkaline elution buffers. In preferred embodiments, the method according to the invention enables the isolation of phosphopeptides from complex sample solutions with a reproducibly high yield and at the same time with high purity and it allows efficient ionisation and detection of the isolated phosphopeptides both by MALDI-TOF and also by ESI mass spectrometry without additional requisite method steps, such as, for example, chromatographic desalination of the sample.
    Type: Application
    Filed: April 21, 2005
    Publication date: October 4, 2007
    Inventors: Jonas Anders, Achim Schwammle, Sven Andrecht, Robertus Hendriks, Anette Boerner, Cora Rueter
  • Publication number: 20070148651
    Abstract: The present invention relates to a method and a kit for the isolation of RNA in the presence of DNA. The isolation is carried out by binding to a magnetite solid phase, where the binding buffer produces a concentration of guanidinium thiocyanate of>2.5 mol/l, and a certain concentration of phosphate is present during the binding.
    Type: Application
    Filed: November 12, 2004
    Publication date: June 28, 2007
    Inventors: Uwe Michelsen, Karl Holschuh, Achim Schwammle
  • Publication number: 20030157653
    Abstract: The present invention relates to a process for the production of monoglycosidated flavonoids by enzymatic hydrolysis of rutinosides, in which the enzymatic hydrolysis is carried out using an enzyme immobilized on a support. This process can avoid high enzyme costs whilst at the same time a high degree of automation, combined with high space-time yields is achieved.
    Type: Application
    Filed: December 4, 2002
    Publication date: August 21, 2003
    Inventors: Hans Leonard Ohrem, Achim Schwammle