Patents by Inventor Ad de Groof

Ad de Groof has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210162036
    Abstract: The present invention relates to the use of a diluent for the in-use stabilisation of cells infected with a cell-associated alphaherpesvims. Contrary to the long-standing practice of incorporating a considerable amount of peptone into the diluent for such virus-infected cells, it was found that a reduction of the amount of protein in the diluent improved the in-use stability of alphaherpesvirus-infected cells. Whereby the best stability was even obtained using a protein-free diluent. This effect was especially pronounced for recombinant HVT viruses expressing a heterologous insert. Being protein-free is highly advantageous for the production of the diluent, in respect of costs, safety, and consistency of production.
    Type: Application
    Filed: December 19, 2018
    Publication date: June 3, 2021
    Applicant: Intervet Inc.
    Inventors: Ad DE GROOF, Iwan VERSTEGEN
  • Patent number: 10954491
    Abstract: The present invention relates to a novel porcine pestivirus, to proteins of the virus and to vaccines based upon the virus and proteins thereof. The invention also relates to DNA fragments comprising a gene of the virus and to DNA vaccines based upon genes of the virus. Furthermore the invention relates to antibodies that are reactive with the novel virus and to diagnostic tests for the detection of the virus or antibodies against the virus.
    Type: Grant
    Filed: December 18, 2015
    Date of Patent: March 23, 2021
    Assignee: Intervet Inc.
    Inventors: Ad de Groof, Lars Guelen, Carla Christina Schrier, Martin Deijs, Cornelia Maria van der Hoek
  • Patent number: 10398773
    Abstract: The present invention relates to a novel porcine parvovirus, to proteins of the virus and to vaccines based upon the virus and proteins thereof. The invention also relates to DNA fragments comprising a gene of the virus and to DNA vaccines based upon genes of the virus. Further the invention relates to antibodies that are reactive with the novel virus and to diagnostic tests for the detection of the virus or antibodies against the virus.
    Type: Grant
    Filed: April 16, 2015
    Date of Patent: September 3, 2019
    Assignee: Intervet Inc.
    Inventors: Lars Guelen, Ad de Groof, Carla Christina Schrier, Martin Deijs, Cornelia Maria Hoek Van Der
  • Publication number: 20170342387
    Abstract: The present invention relates to a novel porcine pestivirus, to proteins of the virus and to vaccines based upon the virus and proteins thereof. The invention also relates to DNA fragments comprising a gene of the virus and to DNA vaccines based upon genes of the virus. Furthermore the invention relates to antibodies that are reactive with the novel virus and to diagnostic tests for the detection of the virus or antibodies against the virus.
    Type: Application
    Filed: December 18, 2015
    Publication date: November 30, 2017
    Applicant: Intervet Inc.
    Inventors: Ad de Groof, Lars Guelen, Carla Christina Schrier, Martin Deijs, Cornelia Maria van der Hoek