Patents by Inventor Ad Ijzerman

Ad Ijzerman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7189706
    Abstract: The present invention concerns novel C2,5?-disubstituted and N6,C2,5?-trisubstituted adenosine derivatives and their different uses. These adenosine derivatives were found to be potent adenosine receptor agonists and thus are of a therapeutic value in the treatment and prophylaxis of diseases and disorders affected by adenosine receptor agonists.
    Type: Grant
    Filed: September 3, 2003
    Date of Patent: March 13, 2007
    Assignees: Universiteit Leiden, Can-Fite Biopharma Ltd.
    Inventors: Erica Van Tilburg, Ad Ijzerman
  • Patent number: 7112574
    Abstract: Novel C2,8-disubstituted adenosine derivatives disclosed herein have been found to be potent adenosine receptor agonists, in particular for the A2A receptor. The said compounds have biological activity against conditions such as hypertension, ischemic heart disease, ischemic brain disease, psychosis and wound healing. Further, the invention also discloses a process for the preparation of such compounds and pharmaceutical compositions comprising them.
    Type: Grant
    Filed: March 3, 2002
    Date of Patent: September 26, 2006
    Assignees: Universiteit Leiden, Can-Fite Biopharma Ltd.
    Inventors: Erica Van Tilburg, Ad Ijzerman
  • Patent number: 7084127
    Abstract: The present invention concerns novel C2,5?-disubstituted and N6?,C2,5?-trisubstituted adenosine derivatives and their different uses. These adenosine derivatives were found to be potent adenosine receptor agonists and thus are of a therapeutic value in the treatment and prophylaxis of diseases and disorders affected by adenosine receptor agonists.
    Type: Grant
    Filed: March 3, 2002
    Date of Patent: August 1, 2006
    Assignees: Universiteit Leiden, Can-Fite Biopharma Ltd.
    Inventors: Erica Van Tilburg, Ad Ijzerman
  • Publication number: 20040132686
    Abstract: The present invention concerns novel C2,5′-disubstituted and N6′,C2,5′-trisubstituted adenosine derivatives and their different uses. These adenosine derivatives were found to be potent adenosine receptor agonists and thus are of a therapeutic value in the treatment and prophylaxis of diseases and disorders affected by adenosine receptor agonists.
    Type: Application
    Filed: March 4, 2004
    Publication date: July 8, 2004
    Inventors: Erica Van Tilburg, Ad Ijzerman
  • Publication number: 20040127452
    Abstract: The present invention concerns novel C2,5′-disubstituted and N6,C2,5′-trisubstituted adenosine derivatives and their different uses. These adenosine derivatives were found to be potent adenosine receptor agonists and thus are of a therapeutic value in the treatment and prophylaxis of diseases and disorders affected by adenosine receptor agonists.
    Type: Application
    Filed: September 3, 2003
    Publication date: July 1, 2004
    Applicants: UNIVERSITEIT LEIDEN, CAN-FITE BIOPHARMA LTD.
    Inventors: Erica Van Tilburg, Ad Ijzerman
  • Publication number: 20040116374
    Abstract: Novel C2, 8-disubstituted adenosine derivatives disclosed herein have been found to be potent adenosine receptor agonists, in particular for the A2A receptor. The said compounds have biological activity against conditions such as hypertension, ischemic heart disease, ischemic brain disease, psychosis and wound healing. Further, the invention also discloses a process for the preparation of such compounds and pharmaceutical compositions comprising them.
    Type: Application
    Filed: February 9, 2004
    Publication date: June 17, 2004
    Inventors: Erica Van Tilburg, Ad Ijzerman