Patents by Inventor Ada Salman

Ada Salman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7592459
    Abstract: The present invention provides a crystalline donepezil maleate, which is used as an intermediate in the preparation of donepezil hydrochloride. Also provided are novel processes for producing same in substantially pure form and a process for producing pharmaceutically pure amorphous donepezil hydrochloride therefrom.
    Type: Grant
    Filed: September 27, 2005
    Date of Patent: September 22, 2009
    Assignee: Chemagis Ltd.
    Inventors: Oded Arad, Lior Zelikovitch, Mohammed Alnabari, Michael Brand, Irina Gribun, Ada Salman, Meital Shiffer, Moty Shookrun, Orna Kurlat, Moshe Bentolila, Joseph Kaspi
  • Publication number: 20060276525
    Abstract: Processes are disclosed for preparing Telmisartan form A, which is free-flowing and which does not contain electrostatic charge and is thus industrially process-able. The free-flowing Telmisartan form A is prepared by crystallization from a polar organic solvent e.g., DMSO, DMF, DMA, NMP, or water and is suitable for use in pharmaceutical compositions. A process is also disclosed for preparing highly-pure Telmisartan form A by precipitation from aqueous solutions.
    Type: Application
    Filed: May 17, 2006
    Publication date: December 7, 2006
    Inventors: Itai Adin, Carmen Iustain, Michael Brand, Ada Salman, Alexander Weisman
  • Publication number: 20060264491
    Abstract: The present invention provides an intermediate and a process for preparing Telmisartan, which overcomes the drawbacks of conventional methods and produces Telmisartan in high purity and yield.
    Type: Application
    Filed: June 8, 2006
    Publication date: November 23, 2006
    Applicant: CHEMAGIS LTD.
    Inventors: Michael Brand, Ada Salman, Yael Gafni, Michal Noiman, Alex Weisman, Joseph Kaspi
  • Publication number: 20060069263
    Abstract: A process is disclosed for the reduction of (S)-2-amino-6-propionamido-4,5,6,7-tetrahydrobenzothiazole, which comprises reacting (S)-2-amino-6-propionamido-4,5,6,7-tetrahydrobenzothiazole with a borane reagent in the presence of suitable organic solvent to yield (S)-2-amino-6-propylamino-4,5,6,7-tetrahydrobenzothiazole base, which may be converted to an acid addition salt thereof. The process provided herein can be easily, conveniently and inexpensively scaled-up.
    Type: Application
    Filed: September 23, 2005
    Publication date: March 30, 2006
    Inventors: Irina Gribun, Ada Salman, Meital Shiffer, Moty Shookrun, Michael Brand, Oded Arad, Joseph Kaspi
  • Publication number: 20060069125
    Abstract: The present invention provides a crystalline donepezil maleate, which is used as an intermediate in the preparation of donepezil hydrochloride. Also provided are novel processes for producing same in substantially pure form and a process for producing pharmaceutically pure amorphous donepezil hydrochloride therefrom.
    Type: Application
    Filed: September 27, 2005
    Publication date: March 30, 2006
    Inventors: Oded Arad, Lior Zelikovitch, Mohammed Alnabari, Michael Brand, Irina Gribun, Ada Salman, Meital Shiffer, Moty Shookrun, Orna Kurlat, Moshe Bentolila, Joseph Kaspi