Patents by Inventor Ada VAILL

Ada VAILL has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bifunctional degraders of galactose-deficient immunoglobulins
    Patent number: 12673111
    Abstract: A composition of matter including a deglycosylated IgA-binding moiety, a cellular receptor-binding moiety that binds to hepatocytes or other degrading cells through asialoglycoprotein receptors (ASGPR) on the surface of hepatocytes or other degrading cells in a patient or subject, and optionally, a linker moiety connecting deglycosylated IgA-binding moiety and the cellular receptor-binding moiety, wherein the composition of matter is useful for removing galactose-deficient IgA1 in a patient or subject.
    Type: Grant
    Filed: February 21, 2025
    Date of Patent: July 7, 2026
    Assignee: Biohaven Therapeutics Ltd.
    Inventors: Gene M. Dubowchik, Ada Vaill, Reese M. Caldwell, Brian M. Linhares, David K. Leahy, James Bryson, Lawrence R. Marcin
  • BIFUNCTIONAL DEGRADERS OF GALACTOSE-DEFICIENT IMMUNOGLOBULINS
    Publication number: 20250228957
    Abstract: A composition of matter including a deglycosylated IgA-binding moiety, a cellular receptor-binding moiety that binds to hepatocytes or other degrading cells through asialoglycoprotein receptors (ASGPR) on the surface of hepatocytes or other degrading cells in a patient or subject, and optionally, a linker moiety connecting deglycosylated IgA-binding moiety and the cellular receptor-binding moiety, wherein the composition of matter is useful for removing galactose-deficient IgA1 in a patient or subject.
    Type: Application
    Filed: February 21, 2025
    Publication date: July 17, 2025
    Inventors: Gene M. DUBOWCHIK, Ada VAILL, Reese M. CALDWELL, Brian M. LINHARES, David K. LEAHY, James BRYSON, Lawrence R. MARCIN