Patents by Inventor Adam Ahmed Abdullah SULAIMAN
Adam Ahmed Abdullah SULAIMAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 11958867Abstract: A gold(III) complex of formula (I) or formula (II) wherein R1 and R2 are each independently a hydrogen, an optionally substituted alkyl, an optionally substituted cycloalkyl, an optionally substituted arylalkyl, or an optionally substituted aryl; R3 and R4 are each independently a hydrogen, an optionally substituted alkyl, an optionally substituted cycloalkyl, an optionally substituted arylalkyl, an optionally substituted aryl, an optionally substituted heterocyclyl, an optionally substituted alkoxy, a hydroxyl, a halo, a nitro, a cyano, a N-monosubstituted amino group, or a N,N-disubstituted amino group; and X is Cl, Br, or I. A pharmaceutical composition containing the gold(III) complex of formula (I) or (II), and a method of treating cancer are included.Type: GrantFiled: May 26, 2022Date of Patent: April 16, 2024Assignee: KING FAHD UNIVERSITY OF PETROLEUM AND MINERALSInventors: Anvarhusein A. Isab, Adam Ahmed Abdullah Sulaiman
-
Patent number: 11571430Abstract: A platinum(II) complex of formula (I), or a pharmaceutically acceptable solvate or tautomer thereof, wherein R1 and R2 are each independently a hydrogen, an optionally substituted alkyl, an optionally substituted cycloalkyl, an optionally substituted arylalkyl, or an optionally substituted aryl; or wherein R1 and R2 together form a five-, six-, or seven-membered ring with the nitrogen atoms to which they are attached; and X is a nitrate anion, a hexafluorophosphate anion, a hexafluoroantimonate anion, a trifluoromethanesulfonate anion, a tetrafluoroborate anion, a perchlorate anion, or a halide anion. A pharmaceutical composition containing the platinum(II) complex of formula (I), and a method of treating cancer are also disclosed.Type: GrantFiled: February 1, 2021Date of Patent: February 7, 2023Assignees: KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS, KING SAUD UNIVERSITYInventors: Adam Ahmed Abdullah Sulaiman, Abdul Rajjak Shaikh, Ali Alhoshani, Anvarhusein A. Isab
-
Publication number: 20220281896Abstract: A gold(III) complex of formula (I) or formula (II) wherein R1 and R2 are each independently a hydrogen, an optionally substituted alkyl, an optionally substituted cycloalkyl, an optionally substituted arylalkyl, or an optionally substituted aryl; R3 and R4 are each independently a hydrogen, an optionally substituted alkyl, an optionally substituted cycloalkyl, an optionally substituted arylalkyl, an optionally substituted aryl, an optionally substituted heterocyclyl, an optionally substituted alkoxy, a hydroxyl, a halo, a nitro, a cyano, a N-monosubstituted amino group, or a N,N-disubstituted amino group; and X is Cl, Br, or I. A pharmaceutical composition containing the gold(III) complex of formula (I) or (II), and a method of treating cancer are included.Type: ApplicationFiled: May 26, 2022Publication date: September 8, 2022Applicant: KING FAHD UNIVERSITY OF PETROLEUM AND MINERALSInventors: Anvarhusein A. ISAB, Adam Ahmed Abdullah SULAIMAN
-
Publication number: 20220281897Abstract: A gold(III) complex of formula (I) or formula (II) wherein R1 and R2 are each independently a hydrogen, an optionally substituted alkyl, an optionally substituted cycloalkyl, an optionally substituted arylalkyl, or an optionally substituted aryl; R3 and R4 are each independently a hydrogen, an optionally substituted alkyl, an optionally substituted cycloalkyl, an optionally substituted arylalkyl, an optionally substituted aryl, an optionally substituted heterocyclyl, an optionally substituted alkoxy, a hydroxyl, a halo, a nitro, a cyano, a N-monosubstituted amino group, or a N,N-disubstituted amino group; and X is Cl, Br, or I. A pharmaceutical composition containing the gold(III) complex of formula (I) or (II), and a method of treating cancer are included.Type: ApplicationFiled: May 26, 2022Publication date: September 8, 2022Applicant: KING FAHD UNIVERSITY OF PETROLEUM AND MINERALSInventors: Anvarhusein A. ISAB, Adam Ahmed Abdullah SULAIMAN
-
Patent number: 11384100Abstract: A gold(III) complex of formula (I) or formula (II) wherein R1 and R2 are each independently a hydrogen, an optionally substituted alkyl, an optionally substituted cycloalkyl, an optionally substituted arylalkyl, or an optionally substituted aryl; R3 and R4 are each independently a hydrogen, an optionally substituted alkyl, an optionally substituted cycloalkyl, an optionally substituted arylalkyl, an optionally substituted aryl, an optionally substituted heterocyclyl, an optionally substituted alkoxy, a hydroxyl, a halo, a nitro, a cyano, a N-monosubstituted amino group, or a N,N-disubstituted amino group; and X is Cl, Br, or I. A pharmaceutical composition containing the gold(III) complex of formula (I) or (II), and a method of treating cancer are included.Type: GrantFiled: August 28, 2019Date of Patent: July 12, 2022Assignee: King Fahd University of Petroleum and MineralsInventors: Anvarhusein A. Isab, Adam Ahmed Abdullah Sulaiman
-
Patent number: 11142539Abstract: Mixed ligand phosphinogold(I) complexes as anticancer agents. The gold(I) ion of the complexes is coordinated to a phosphine and a dithiocarbamate or halogen ligand. Also described are a pharmaceutical composition incorporating the phosphinogold(I) complex, a method of synthesizing the phosphinogold(I) complex, and a method of treating cancer. The phosphinogold(I) complexes exhibit potent cytotoxicity against lung, cervical, and liver cancer cells.Type: GrantFiled: March 10, 2020Date of Patent: October 12, 2021Assignees: King Fahd University of Petroleum and Minerals, King Saud UniversityInventors: Anvarhusein A. Isab, Adam Ahmed Abdullah Sulaiman, Ali Alhoshani
-
Publication number: 20210284674Abstract: Mixed ligand phosphinogold(I) complexes as anticancer agents. The gold(I) ion of the complexes is coordinated to a phosphine and a dithiocarbamate or halogen ligand. Also described are a pharmaceutical composition incorporating the phosphinogold(I) complex, a method of synthesizing the phosphinogold(I) complex, and a method of treating cancer. The phosphinogold(I) complexes exhibit potent cytotoxicity against lung, cervical, and liver cancer cells.Type: ApplicationFiled: March 10, 2020Publication date: September 16, 2021Applicants: King Fahd University of Petroleum and Minerals, King Saud UniversityInventors: Anvarhusein A. ISAB, Adam Ahmed Abdullah SULAIMAN, Ali ALHOSHANI
-
Publication number: 20210283140Abstract: A platinum(II) complex of formula (I), or a pharmaceutically acceptable solvate or tautomer thereof, wherein R1 and R2 are each independently a hydrogen, an optionally substituted alkyl, an optionally substituted cycloalkyl, an optionally substituted arylalkyl, or an optionally substituted aryl; or wherein R1 and R2 together form a five-, six-, or seven-membered ring with the nitrogen atoms to which they are attached; and X is a nitrate anion, a hexafluorophosphate anion, a hexafluoroantimonate anion, a trifluoromethanesulfonate anion, a tetrafluoroborate anion, a perchlorate anion, or a halide anion. A pharmaceutical composition containing the platinum(II) complex of formula (I), and a method of treating cancer are also disclosed.Type: ApplicationFiled: February 1, 2021Publication date: September 16, 2021Applicants: KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS, KING SAUD UNIVERSITYInventors: Adam Ahmed Abdullah SULAIMAN, Abdul Rajjak SHAIKH, Ali ALHOSHANI, Anvarhusein A. ISAB
-
Publication number: 20210284671Abstract: A family of platinum(II) complex with mixed ligands as anticancer agents. The platinum(II) ion is coordinated to dicyclopentadiene and dithiocarbamate ligands. Also described are a pharmaceutical composition incorporating the platinum(II) complex, a methods of synthesizing the platinum(II) complex, and a method of treating cancer. The platinum(II) complexes exhibit potent cytotoxicity against lung and cervical cancer cell lines as well as low nephrotoxicity.Type: ApplicationFiled: March 10, 2020Publication date: September 16, 2021Applicants: King Fahd University of Petroleum and Minerals, King Saud UniversityInventors: Adam Ahmed Abdullah Sulaiman, Ali Alhoshani, Anvarthusein A. Isab
-
Patent number: 11117912Abstract: A family of platinum(II) complex with mixed ligands as anticancer agents. The platinum(II) ion is coordinated to dicyclopentadiene and dithiocarbamate ligands. Also described are a pharmaceutical composition incorporating the platinum(II) complex, a methods of synthesizing the platinum(II) complex, and a method of treating cancer. The platinum(II) complexes exhibit potent cytotoxicity against lung and cervical cancer cell lines as well as low nephrotoxicity.Type: GrantFiled: March 10, 2020Date of Patent: September 14, 2021Assignees: King Fahd University of Petroleum and Minerals, King Saud UniversityInventors: Adam Ahmed Abdullah Sulaiman, Ali Alhoshani, Anvarhusein A. Isab
-
Publication number: 20210061818Abstract: A gold(III) complex of formula (I) or formula (II) wherein R1 and R2 are each independently a hydrogen, an optionally substituted alkyl, an optionally substituted cycloalkyl, an optionally substituted arylalkyl, or an optionally substituted aryl; R3 and R4 are each independently a hydrogen, an optionally substituted alkyl, an optionally substituted cycloalkyl, an optionally substituted arylalkyl, an optionally substituted aryl, an optionally substituted heterocyclyl, an optionally substituted alkoxy, a hydroxyl, a halo, a nitro, a cyano, a N-monosubstituted amino group, or a N,N-disubstituted amino group; and X is Cl, Br, or I. A pharmaceutical composition containing the gold(III) complex of formula (I) or (II), and a method of treating cancer are included.Type: ApplicationFiled: August 28, 2019Publication date: March 4, 2021Applicant: King Fahd University of Petroleum and MineralsInventors: Anvarhusein A. ISAB, Adam Ahmed Abdullah SULAIMAN