Abstract: An assembly for a portable blender. The assembly having a housing that is configured for coupling to a container. The assembly has at least one battery, a motor electrically connected to the battery, a blade coupled to the motor, and a user input device operable to cause power to be sent from the battery to the motor so that the motor rotates the blade. At least a portion of the blade is positioned outside of the housing so that the blade is configured to be positioned in an interior space of the container when the housing is coupled to the container. The assembly may include a plurality of batteries each positioned radially outward from the motor with the batteries positioned circumferentially around the motor. A portable blender including the assembly and a container. The container having a dual-wall, vacuum insulated construction.

Abstract: The present invention provides compositions and methods for treating cancers with reduced or absent CDH1 using a RHOA dominant negative polypeptide or biologically active fragment thereof, and/or a nucleic acid encoding a RHOA dominant negative polypeptide or biologically active fragment thereof.

Abstract: An assembly for a portable blender. The assembly having a housing that is configured for coupling to a container. The assembly has at least one battery, a motor electrically connected to the battery, a blade coupled to the motor, and a user input device operable to cause power to be sent from the battery to the motor so that the motor rotates the blade. At least a portion of the blade is positioned outside of the housing so that the blade is configured to be positioned in an interior space of the container when the housing is coupled to the container. The assembly may include a plurality of batteries each positioned radially outward from the motor with the batteries positioned circumferentially around the motor. A portable blender including the assembly and a container. The container having a dual-wall, vacuum insulated construction.

Abstract: An assembly for a portable blender. The assembly having a housing that is configured for coupling to a container. The assembly has at least one battery, a motor electrically connected to the battery, a blade coupled to the motor, and a user input device operable to cause power to be sent from the battery to the motor so that the motor rotates the blade. At least a portion of the blade is positioned outside of the housing so that the blade is configured to be positioned in an interior space of the container when the housing is coupled to the container. The assembly may include a plurality of batteries each positioned radially outward from the motor with the batteries positioned circumferentially around the motor. A portable blender including the assembly and a container. The container having a dual-wall, vacuum insulated construction.

Abstract: The present disclosure relates to compositions and methods for the diagnosis and treatment or prevention of microsatellite unstable cancers. In particular, the instant disclosure provides for identification of a cancer as exhibiting microsatellite instability (MSI) and/or impaired mismatch repair (MMR), and selection and/or administration of an inhibitor of the WRN helicase as a therapeutic agent for such a cancer and/or subject having or at risk of developing such a cancer.

Abstract: The present invention is based on the identification of novel biomarkers predictive of responsiveness of esophagogastric cancers to inhibitors of the PD-1 pathway.

Abstract: The present invention provides compositions and methods for treating cancers with reduced or absent CDH1 using a RHOA dominant negative polypeptide or biologically active fragment thereof, and/or a nucleic acid encoding a RHOA dominant negative polypeptide or biologically active fragment thereof.

Abstract: The present invention is based on the identification of novel biomarkers predictive of responsiveness of esophagogastric cancers to inhibitors of the PD-1 pathway.