Patents by Inventor Adam C. Straub

Adam C. Straub has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Targeting Cyb5R3
    Patent number: 10568886
    Abstract: A method for regulating arterial vascular tone in a subject, comprising administering to a subject in need thereof, a therapeutically effective amount of a compound, or a pharmaceutically acceptable salt thereof, having a structure of: wherein A and B are each individually selected from O or S; a is 1 to 4; and Ar is optionally substituted aryl or optionally substituted heteroaryl.
    Type: Grant
    Filed: September 11, 2015
    Date of Patent: February 25, 2020
    Assignee: University of Pittsburgh—Of the Commonwealth System of Higher Education
    Inventors: Adam C. Straub, Carlos J. Camacho, Mizanur Rahaman, Fabio Reinders
  • Compositions and methods for regulating arterial tone
    Patent number: 10253069
    Abstract: The present invention provides compositions and methods for regulating arterial tone based on the discovery herein of novel expression and regulation of hemoglobin alpha and cytochrome B5 reductase 3 and the effects on NO and NOS.
    Type: Grant
    Filed: July 7, 2017
    Date of Patent: April 9, 2019
    Assignee: University of Virginia Patent Foundation
    Inventors: Benjamin M. Gaston, Adam C. Straub, Brant E. Isakson, Linda Columbus
  • COMPOSITIONS AND METHODS FOR REGULATING ARTERIAL TONE
    Publication number: 20180022779
    Abstract: The present invention provides compositions and methods for regulating arterial tone based on the discovery herein of novel expression and regulation of hemoglobin alpha and cytochrome B5 reductase 3 and the effects on NO and NOS.
    Type: Application
    Filed: July 7, 2017
    Publication date: January 25, 2018
    Applicant: University of Virginia Patent Foundation
    Inventors: Benjamin M. Gaston, Adam C. Straub, Brant E. Isakson, Linda Columbus
  • TARGETING CYB5R3
    Publication number: 20170224686
    Abstract: A method for regulating arterial vascular tone in a subject, comprising administering to a subject in need thereof, a therapeutically effective amount of a compound, or a pharmaceutically acceptable salt thereof, having a structure of: wherein A and B are each individually selected from O or S; a is 1 to 4; and Ar is optionally substituted aryl or optionally substituted heteroaryl.
    Type: Application
    Filed: September 11, 2015
    Publication date: August 10, 2017
    Applicant: University of Pittsburgh - Of the Commonwealth Sys tem of Higher Education
    Inventors: Adam C. Straub, Carlos J. Camacho, Mizanur Rahaman, Fabio Reinders
  • Compositions and methods for regulating arterial tone
    Patent number: 9701714
    Abstract: The present invention provides compositions and methods for regulating arterial tone based on the discovery herein of novel expression and regulation of hemoglobin alpha and cytochrome B5 reductase 3 and the effects on NO and NOS.
    Type: Grant
    Filed: October 22, 2013
    Date of Patent: July 11, 2017
    Assignee: University of Virginia Patent Foundation
    Inventors: Benjamin M. Gaston, Adam C. Straub, Brant E. Isakson, Linda Columbus
  • COMPOSITIONS AND METHODS FOR REGULATING ARTERIAL TONE
    Publication number: 20150274779
    Abstract: The present invention provides compositions and methods for regulating arterial tone based on the discovery herein of novel expression and regulation of hemoglobin alpha and cytochrome B5 reductase 3 and the effects on NO and NOS.
    Type: Application
    Filed: October 22, 2013
    Publication date: October 1, 2015
    Applicant: University of Virginia Patent Foundation
    Inventors: Benjamin M. Gaston, Adam C. Straub, Brant E. Isakson, Linda Columbus