Patents by Inventor Adam Culley

Adam Culley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12227802
    Abstract: Embodiments of the present disclosure relate to nucleotide molecules with a 3? AOM blocking group. Also provided herein are methods to prepare such nucleotide molecules, and the uses of fully functionalized nucleotides containing the 3?-OH blocking group for sequencing applications.
    Type: Grant
    Filed: October 17, 2023
    Date of Patent: February 18, 2025
    Assignee: Illumina Cambridge Limited
    Inventors: Antoine Francais, Elena Cressina, Adam Culley, Angelica Mariani, Xiaolin Wu, Xiaohai Liu
  • Publication number: 20240209015
    Abstract: Embodiments of the present disclosure relate to nucleotide and nucleoside molecules with acetal or allyl 3? blocking groups. Also provided herein are methods to prepare such nucleotide and nucleoside molecules, and the uses of fully functionalized nucleotides containing the 3? blocking groups for sequencing applications.
    Type: Application
    Filed: December 21, 2023
    Publication date: June 27, 2024
    Inventors: Antoine Francais, Elena Cressina, Angelica Mariani, Adam Culley, Anno Koetje, Xiaohai Liu, Xiaolin Wu, Kathryn Hattingh
  • Publication number: 20240182963
    Abstract: Embodiments of the present disclosure relate to nucleotide and nucleoside molecules with 3? acetal, thiocarbamate or allyl blocking groups. Also provided herein are methods to prepare such nucleotide and nucleoside molecules, and the uses of fully functionalized nucleotides containing the 3?-OH blocking group for sequencing applications.
    Type: Application
    Filed: December 21, 2023
    Publication date: June 6, 2024
    Inventors: Antoine Francais, Elena Cressina, Adam Culley, Angelica Mariani, Xiaolin Wu, Xiaohai Liu, Kathryn Hattingh
  • Publication number: 20240150827
    Abstract: Embodiments of the present disclosure relate to nucleotide molecules with a 3? AOM blocking group. Also provided herein are methods to prepare such nucleotide molecules, and the uses of fully functionalized nucleotides containing the 3?-OH blocking group for sequencing applications.
    Type: Application
    Filed: October 17, 2023
    Publication date: May 9, 2024
    Inventors: Antoine FRANCAIS, Elena CRESSINA, Adam CULLEY, Angelica MARIANI, Xiaolin WU, Xiaohai LIU
  • Publication number: 20240132532
    Abstract: Embodiments of the present disclosure relate to nucleotide with acetal 3?-OH blocking groups. Also provided herein are methods of using fully functionalized nucleotides containing the 3? acetal blocking group for sequencing applications.
    Type: Application
    Filed: September 28, 2023
    Publication date: April 25, 2024
    Inventors: Antoine FRANCAIS, Elena CRESSINA, Angelica MARIANI, Adam CULLEY, Anno KOETJE, Xiaohai LIU
  • Patent number: 11827931
    Abstract: Embodiments of the present disclosure relate to methods of preparing growing polynucleotides using nucleotide molecules with a 3? AOM blocking group. Also provided herein are kits related to such methods.
    Type: Grant
    Filed: March 30, 2022
    Date of Patent: November 28, 2023
    Assignee: Illumina Cambridge Limited
    Inventors: Antoine Francais, Elena Cressina, Adam Culley, Angelica Mariani, Xiaolin Wu, Xiaohai Liu
  • Patent number: 11787831
    Abstract: Embodiments of the present disclosure relate to nucleotide and nucleoside molecules with acetal 3?-OH blocking groups. Also provided herein are methods to prepare such nucleotide and nucleoside molecules, and the uses of fully functionalized nucleotides containing the 3? acetal blocking group for sequencing applications.
    Type: Grant
    Filed: June 21, 2021
    Date of Patent: October 17, 2023
    Assignee: Illumina Cambridge Limited
    Inventors: Antoine Francais, Elena Cressina, Angelica Mariani, Adam Culley, Anno Koetje, Xiaohai Liu
  • Publication number: 20220220553
    Abstract: Embodiments of the present disclosure relate to nucleotide molecules with a 3? AOM blocking group. Also provided herein are methods to prepare such nucleotide molecules, and the uses of fully functionalized nucleotides containing the 3?-OH blocking group for sequencing applications.
    Type: Application
    Filed: March 30, 2022
    Publication date: July 14, 2022
    Inventors: Antoine FRANCAIS, Elena CRESSINA, Adam CULLEY, Angelica MARIANI, Xiaolin WU, Xiaohai LIU
  • Patent number: 11293061
    Abstract: Embodiments of the present disclosure relate to sequencing methods using nucleotide molecules with a 3? AOM blocking group, which can provide reduced phasing and pre-phasing values. Also provided herein are kits related to such sequencing methods.
    Type: Grant
    Filed: December 20, 2019
    Date of Patent: April 5, 2022
    Assignee: Illumina Cambridge Limited
    Inventors: Antoine Francais, Elena Cressina, Adam Culley, Angelica Mariani, Xiaolin Wu, Xiaohai Liu
  • Publication number: 20210403500
    Abstract: Embodiments of the present disclosure relate to nucleotide and nucleoside molecules with acetal 3?-OH blocking groups. Also provided herein are methods to prepare such nucleotide and nucleoside molecules, and the uses of fully functionalized nucleotides containing the 3? acetal blocking group for sequencing applications.
    Type: Application
    Filed: June 21, 2021
    Publication date: December 30, 2021
    Inventors: Antoine FRANCAIS, Elena CRESSINA, Angelica MARIANI, Adam CULLEY, Anno KOETJE, Xiaohai LIU
  • Publication number: 20200216891
    Abstract: Embodiments of the present disclosure relate to nucleotide and nucleoside molecules with acetal or thiocarbamate 3?-OH blocking groups. Also provided herein are methods to prepare such nucleotide and nucleoside molecules, and the uses of fully functionalized nucleotides containing the 3?-OH blocking group for sequencing applications.
    Type: Application
    Filed: December 20, 2019
    Publication date: July 9, 2020
    Inventors: Antoine FRANCAIS, Elena CRESSINA, Adam CULLEY, Angelica MARIANI, Xiaolin WU, Xiaohai LIU
  • Publication number: 20180347819
    Abstract: A fireplace with a removable door includes a hemispherically shaped firebox with a flat, sloped front face with an opening therethrough to allow access to the firebox, with a protruding lip extending along the lower edge of the flat front face beneath the opening. A removable glass panel door positioned against the flat front face and supported on the protruding lip covers the front opening. A latching mechanism secures the door against the front face by rotating an extending arm to engage against the interior side of the front face. Alternative embodiments having a mesh screen door, a vent in the firebox, a grate integrated into the firebox, and an eccentrically positioned chimney with a damper are also described.
    Type: Application
    Filed: June 6, 2017
    Publication date: December 6, 2018
    Inventors: Scott Hunter, III, Adam Culley