Patents by Inventor Adam D. Linstedt

Adam D. Linstedt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cell-based screening and compounds that modulate GalNAc-transferases
    Patent number: 11730730
    Abstract: Provided herein are small molecule-inhibitors of site-specific O-glycosylation and the identification of such using cell-based fluorescent biosensors. Also provided herein are methods of treating kidney disease and cancer, such as breast cancer.
    Type: Grant
    Filed: May 26, 2021
    Date of Patent: August 22, 2023
    Assignee: Carnegie Mellon University
    Inventors: Adam D. Linstedt, Lina Song, Collin Bachert
  • Cell-Based Screening and Compounds that Modulate GalNAc-Transferases
    Publication number: 20210283124
    Abstract: Provided herein are small molecule-inhibitors of site-specific O-glycosylation and the identification of such using cell-based fluorescent biosensors. Also provided herein are methods of treating kidney disease and cancer, such as breast cancer.
    Type: Application
    Filed: May 26, 2021
    Publication date: September 16, 2021
    Inventors: Adam D. Linstedt, Lina Song, Collin Bachert
  • Cell-based screening and compounds that modulate GaINAc-transferases
    Patent number: 11058675
    Abstract: Provided herein are small molecule-inhibitors of site-specific O-glycosylation and the identification of such using cell-based fluorescent biosensors. Also provided herein are methods of treating kidney disease and cancer, such as breast cancer.
    Type: Grant
    Filed: March 29, 2019
    Date of Patent: July 13, 2021
    Assignee: Carnegie Mellon University
    Inventors: Adam D. Linstedt, Lina Song, Collin Bachert
  • Cell-Based Screening and Compounds that Modulate GalNAc-Transferases
    Publication number: 20190298711
    Abstract: Provided herein are small molecule-inhibitors of site-specific O-glycosylation and the identification of such using cell-based fluorescent biosensors. Also provided herein are methods of treating kidney disease and cancer, such as breast cancer.
    Type: Application
    Filed: March 29, 2019
    Publication date: October 3, 2019
    Inventors: Adam D. Linstedt, Lina Song, Collin Bachert
  • Methods and compositions for reducing Shiga toxin induced toxicity in mammals
    Patent number: 9439438
    Abstract: Manganese compositions effective in reducing Shiga toxin-induced toxicity in mammals infected with Shiga toxin-producing bacteria such as E. coli O157:H7 are described. Manganese compositions described herein can be combined with antibiotic therapy as manganese can block the toxic effects of Shiga toxin released from dying bacteria.
    Type: Grant
    Filed: January 18, 2012
    Date of Patent: September 13, 2016
    Assignee: Carnegie Mellon University
    Inventors: Adam D. Linstedt, Somshuvra Mukhopadhyay
  • METHODS AND COMPOSITIONS FOR REDUCING SHIGA TOXIN INDUCED TOXICITY IN MAMMALS
    Publication number: 20140127324
    Abstract: Manganese compositions effective in reducing Shiga toxin-induced toxicity in mammals infected with Shiga toxin-producing bacteria such as E. coli O157:H7 are described. Manganese compositions described herein can be combined with antibiotic therapy as manganese can block the toxic effects of Shiga toxin released from dying bacteria.
    Type: Application
    Filed: January 18, 2012
    Publication date: May 8, 2014
    Applicant: CARNEGIE MELLON UNIVERSITY
    Inventors: Adam D. Linstedt, Somshuvra Mukhopadhyay