Patents by Inventor Adam D. Mendelsohn

Adam D. Mendelsohn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Drug delivery device
    Patent number: 11931453
    Abstract: Embodiments of the invention include devices, compositions and methods for the controlled release of therapeutic substances, such as drugs. Control over the rate of release of the therapeutic substances from the devices is achieved by the use of nanoporous membranes in which the pore size is matched to the molecular diameter of the therapeutic substances. Some embodiments of the invention achieve zero-order release by the use of membranes with a pore diameter that is more than five times the Stokes' diameter of the therapeutic substance released.
    Type: Grant
    Filed: September 7, 2021
    Date of Patent: March 19, 2024
    Assignee: Nano Precision Medical, Inc.
    Inventors: Adam D. Mendelsohn, Kathleen E. Fischer, Tomoyuki Yoshie, Wouter Roorda
  • DRUG DELIVERY DEVICE
    Publication number: 20210401735
    Abstract: Embodiments of the invention include devices, compositions and methods for the controlled release of therapeutic substances, such as drugs. Control over the rate of release of the therapeutic substances from the devices is achieved by the use of nanoporous membranes in which the pore size is matched to the molecular diameter of the therapeutic substances. Some embodiments of the invention achieve zero-order release by the use of membranes with a pore diameter that is more than five times the Stokes' diameter of the therapeutic substance released.
    Type: Application
    Filed: September 7, 2021
    Publication date: December 30, 2021
    Applicant: NANO PRECISION MEDICAL, INC.
    Inventors: Adam D. Mendelsohn, Kathleen E. Fischer, Tomoyuki Yoshie, Wouter Roorda
  • Drug delivery device
    Patent number: 11129791
    Abstract: Embodiments of the invention include devices, compositions and methods for the controlled release of therapeutic substances, such as drugs. Control over the rate of release of the therapeutic substances from the devices is achieved by the use of nanoporous membranes in which the pore size is matched to the molecular diameter of the therapeutic substances. Some embodiments of the invention achieve zero-order release by the use of membranes with a pore diameter that is more than five times the Stokes' diameter of the therapeutic substance released.
    Type: Grant
    Filed: November 29, 2018
    Date of Patent: September 28, 2021
    Assignee: NANO PRECISION MEDICAL, INC.
    Inventors: Adam D. Mendelsohn, Kathleen E Fischer, Tomoyuki Yoshie, Wouter E. Roorda
  • APPARATUS AND METHOD FOR PROMOTING FLUID UPTAKE INTO AN IMPLANT
    Publication number: 20200139099
    Abstract: The invention pertains to apparatuses, means and methods to promote uptake of fluids into a reservoir of an implantable drug delivery system though a porous membrane. Embodiments of the invention promote fluid uptake by creating a pressure differential between the reservoir of the drug delivery device and the environment of the device after implantation, for instance a subcutaneous pocket.
    Type: Application
    Filed: January 6, 2020
    Publication date: May 7, 2020
    Applicant: Nano Precision Medical, Inc.
    Inventors: Wouter E. Roorda, William G.M. Fischer, Kathleen Fischer, Adam D. Mendelsohn, Adam Monkowski
  • Apparatus and method for promoting fluid uptake into an implant
    Patent number: 10525248
    Abstract: The invention pertains to apparatuses, means and methods to promote uptake of fluids into a reservoir of an implantable drug delivery system though a porous membrane. Embodiments of the invention promote fluid uptake by creating a pressure differential between the reservoir of the drug delivery device and the environment of the device after implantation, for instance a subcutaneous pocket.
    Type: Grant
    Filed: January 30, 2017
    Date of Patent: January 7, 2020
    Assignee: NANO PRECISION MEDICAL, INC.
    Inventors: Wouter E. Roorda, William G. M. Fischer, Kathleen Fischer, Adam D. Mendelsohn, Adam Monkowski
  • DRUG DELIVERY DEVICE
    Publication number: 20190091140
    Abstract: Embodiments of the invention include devices, compositions and methods for the controlled release of therapeutic substances, such as drugs. Control over the rate of release of the therapeutic substances from the devices is achieved by the use of nanoporous membranes in which the pore size is matched to the molecular diameter of the therapeutic substances. Some embodiments of the invention achieve zero-order release by the use of membranes with a pore diameter that is more than five times the Stokes' diameter of the therapeutic substance released.
    Type: Application
    Filed: November 29, 2018
    Publication date: March 28, 2019
    Applicant: Nano Precision Medical, Inc.
    Inventors: Adam D. Mendelsohn, Kathleen E Fischer, Tomoyuki Yoshie, Wouter E. Roorda
  • Device having titania nanotube membrane for drug delivery
    Patent number: 9814867
    Abstract: The present invention provides a device including a titania nanotube membrane having a plurality of titania nanotubes on a titanium substrate where the titania nanotubes are open at both ends and capable of allowing diffusion of liquids or solids from one side of the membrane to the other through the titania nanotubes. Methods of making the titania nanotube membrane are also provided.
    Type: Grant
    Filed: December 5, 2012
    Date of Patent: November 14, 2017
    Assignee: NANO PRECISION MEDICAL, INC.
    Inventors: Adam D. Mendelsohn, Kathleen E. Fischer, Lily H. Peng, William G. Fischer
  • Implant device for drug delivery
    Patent number: 9770412
    Abstract: The present invention provides a method for controlling the internal diameter of nanopores to afford nanopore membranes with a zero-order rate of release of a therapeutic agent.
    Type: Grant
    Filed: January 23, 2015
    Date of Patent: September 26, 2017
    Assignee: NANO PRECISION MEDICAL, INC.
    Inventors: Adam D. Mendelsohn, Kathleen Fischer, Tomoyuki Yoshie
  • Apparatus and Method for Promoting Fluid Uptake Into an Implant
    Publication number: 20170136224
    Abstract: The invention pertains to apparatuses, means and methods to promote uptake of fluids into a reservoir of an implantable drug delivery system though a porous membrane. Embodiments of the invention promote fluid uptake by creating a pressure differential between the reservoir of the drug delivery device and the environment of the device after implantation, for instance a subcutaneous pocket.
    Type: Application
    Filed: January 30, 2017
    Publication date: May 18, 2017
    Applicant: Nano Precision Medical, Inc.
    Inventors: Wouter E. Roorda, William G.M. Fischer, Kathleen Fischer, Adam D. Mendelsohn, Adam Monkowski
  • IMPLANT DEVICE FOR DRUG DELIVERY
    Publication number: 20170000731
    Abstract: The present invention provides a method for controlling the internal diameter of nanopores to afford nanopore membranes with a zero-order rate of release of a therapeutic agent.
    Type: Application
    Filed: January 23, 2015
    Publication date: January 5, 2017
    Inventors: Adam D. Mendelsohn, Kathleen Fischer, Tomoyuki Yoshie
  • DEVICE HAVING TITANIA NANOTUBE MEMBRANE FOR DRUG DELIVERY
    Publication number: 20140371687
    Abstract: The present invention provides a device including a titania nanotube membrane having a plurality of titania nanotubes on a titanium substrate where the titania nanotubes are open at both ends and capable of allowing diffusion of liquids or solids from one side of the membrane to the other through the titania nanotubes. Methods of making the titania nanotube membrane are also provided.
    Type: Application
    Filed: December 5, 2012
    Publication date: December 18, 2014
    Inventors: Adam D. Mendelsohn, Kathleen E. Fischer, Lily H. Peng, William G. Fischer