Abstract: A method for managing a supply chain may include acquiring property data regarding the supply chain, acquiring one or more objectives to be achieved by the supply chain, the supply chain including a plurality of supply chain entities including customers, manufacturing facilities, and distributing facilities, and a plurality of edges connecting the supply chain entities. The method may also include establishing a first supply chain model for the supply chain in a first geographic resolution based on the property data, determining a first solution for the first supply chain model, establishing a second supply chain model for the supply chain in a second and finer geographic resolution based on the first solution, determining a second solution for the second supply chain model, manufacturing products by manufacturing facilities based on the second solution, and distributing the manufactured products by the distributing facilities and edges based on the second solution.