Patents by Inventor Adam David ROSENTHAL

Adam David ROSENTHAL has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12187797
    Abstract: Provided herein are antibodies that bind signal regulatory protein gamma (SIRP?), as well as SIRP? and/or SIRP?1, and methods of using such antibodies (referred to as SIRP antibodies). In some embodiments, the SIRP antibodies are human monoclonal antibodies that bind human SIRP? as well as SIRP? and/or SIRP?1. In some embodiments, the SIRP antibodies provided herein are useful for treating a disease or condition associated with overactivation and/or hyperproliferation of lymphocytes, myeloid cells, or a combination thereof, or a disease or condition associated with SIRP?, SIRP?1 and/or SIRP? activity.
    Type: Grant
    Filed: February 28, 2024
    Date of Patent: January 7, 2025
    Assignee: Electra Therapeutics, Inc.
    Inventors: Sandip Panicker, Adam David Rosenthal, Eileen Lingshu Rose
  • Publication number: 20240425613
    Abstract: Provided here are antibodies that bind Protein S, and methods of making and using such antibodies. In some embodiments, the Protein S antibodies provided herein are useful for treating a bleeding disorder or platelet disorder, or a condition characterized by reduced or impaired blood coagulation and/or clotting.
    Type: Application
    Filed: August 27, 2024
    Publication date: December 26, 2024
    Inventors: Sandip PANICKER, Adam David ROSENTHAL, Tony Sang Young BYUN, Quehuong Thi DONG
  • Publication number: 20240400677
    Abstract: Provided herein are antibodies that bind signal regulatory protein SIRP? and methods of making and using such antibodies. In some embodiments, the antibodies comprise an Fc, and are useful for preferential depletion of certain SIRP? expressing cells. In some embodiments, the antibodies provided herein are useful for treating a disease or condition associated with the dysregulation of cells (e.g. overactivation or aberrant proliferation of T-cells).
    Type: Application
    Filed: May 9, 2024
    Publication date: December 5, 2024
    Inventors: Sandip PANICKER, Adam David ROSENTHAL, Eileen Lingshu ROSE, Allen Guo Yang CAI
  • Patent number: 12145999
    Abstract: Provided here are antibodies that bind Protein S, and methods of making and using such antibodies. In some embodiments, the Protein S antibodies provided herein are useful for treating a bleeding disorder or platelet disorder, or a condition characterized by reduced or impaired blood coagulation and/or clotting.
    Type: Grant
    Filed: November 10, 2023
    Date of Patent: November 19, 2024
    Assignee: Vega Therapeutics, Inc.
    Inventors: Sandip Panicker, Adam David Rosenthal, Tony Sang Young Byun
  • Publication number: 20240239888
    Abstract: Provided herein are antibodies that bind signal regulatory protein gamma (SIRP?), as well as SIRP? and/or SIRP?1, and methods of using such antibodies (referred to as SIRP antibodies). In some embodiments, the SIRP antibodies are human monoclonal antibodies that bind human SIRP? as well as SIRP? and/or SIRP?1. In some embodiments, the SIRP antibodies provided herein are useful for treating a disease or condition associated with overactivation and/or hyperproliferation of lymphocytes, myeloid cells, or a combination thereof, or a disease or condition associated with SIRP?, SIRP?1 and/or SIRP? activity.
    Type: Application
    Filed: February 28, 2024
    Publication date: July 18, 2024
    Inventors: Sandip PANICKER, Adam David ROSENTHAL, Eileen Lingshu ROSE
  • Publication number: 20240084038
    Abstract: Provided here are antibodies that bind Protein S, and methods of making and using such antibodies. In some embodiments, the Protein S antibodies provided herein are useful for treating a bleeding disorder or platelet disorder, or a condition characterized by reduced or impaired blood coagulation and/or clotting.
    Type: Application
    Filed: November 10, 2023
    Publication date: March 14, 2024
    Inventors: Sandip PANICKER, Adam David ROSENTHAL, Tony Sang Young BYUN, Quehuong Thi DONG
  • Publication number: 20230303685
    Abstract: Provided herein are antibodies that bind signal regulatory protein gamma (SIRPy), as well as SIRP? and/or SIRP?1, and methods of using such antibodies (referred to as SIRP antibodies). In some embodiments, the SIRP antibodies are human monoclonal antibodies that bind human SIRPy as well as SIRP? and/or SIRP?1. In some embodiments, the SIRP antibodies provided herein are useful for treating a disease or condition associated with overactivation and/or hyperproliferation of lymphocytes, myeloid cells, or a combination thereof, or a disease or condition associated with SIRP?, SIRP?1 and/or SIRPy activity.
    Type: Application
    Filed: May 10, 2021
    Publication date: September 28, 2023
    Inventors: Sandip PANICKER, Adam David ROSENTHAL, Eileen Lingshu ROSE
  • Publication number: 20230174672
    Abstract: Provided here are antibodies that bind Protein S, and methods of making and using such antibodies. In some embodiments, the Protein S antibodies provided herein are useful for treating a bleeding disorder or platelet disorder, or a condition characterized by reduced or impaired blood coagulation and/or clotting, e.g. by depleting the circulating levels of TFPI, by disrupting a Protein S-TFPI complex, and/or by preventing the formation of a Protein S-TFPI complex.
    Type: Application
    Filed: May 5, 2021
    Publication date: June 8, 2023
    Inventors: Sandip PANICKER, Adam David ROSENTHAL, Tony Sang Young BYUN, Quehuong Thi DONG
  • Publication number: 20230174648
    Abstract: Provided herein are antibodies that bind signal regulatory protein SIRPa, SIRPß1, or a combination of SIRPa and SIRP?1, and methods of using such antibodies. In some embodiments, the antibodies are human monoclonal antibodies that bind human SIRPa and/or SIRP?1. In some embodiments, the antibodies provided herein are useful for treating a disease or condition associated with overactivation and/or hyperproliferation of myeloid cells, or a disease or condition associated with SIRPa and/or SIRP?1 activity.
    Type: Application
    Filed: May 10, 2021
    Publication date: June 8, 2023
    Inventors: Sandip PANICKER, Adam David ROSENTHAL, Eileen Lingshu ROSE
  • Publication number: 20230083243
    Abstract: Provided here are antibodies that bind Protein S, and methods of making and using such antibodies. In some embodiments, the Protein S antibodies provided herein are useful for treating a bleeding disorder or platelet disorder, or a condition characterized by reduced or impaired blood coagulation and/or clotting.
    Type: Application
    Filed: May 5, 2021
    Publication date: March 16, 2023
    Inventors: Sandip PANICKER, Adam David ROSENTHAL, Tony Sang Young BYUN, Quehuong Thi DONG