Patents by Inventor Adam Engler

Adam Engler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method and device for early cancer screening
    Patent number: 12187992
    Abstract: The present disclosure provides a device for assessing adhesion strength of a cancer cell and methods of using the same.
    Type: Grant
    Filed: February 19, 2021
    Date of Patent: January 7, 2025
    Assignee: The Regents of the University of California
    Inventors: Adam Engler, Afsheen Banisadr, Pranjali Beri, Alexander Fuhrmann
  • METHOD AND DEVICE FOR EARLY CANCER SCREENING
    Publication number: 20210253987
    Abstract: The present disclosure provides a device for assessing adhesion strength of a cancer cell and methods of using the same.
    Type: Application
    Filed: February 19, 2021
    Publication date: August 19, 2021
    Inventors: Adam Engler, Afsheen Banisadr, Pranjali Beri, Alexander Fuhrmann
  • SYSTEMS AND METHODS OF DISEASE MODELING USING STATIC AND TIME-DEPENDENT HYDROGELS
    Publication number: 20170328889
    Abstract: Provided are methods and devices for the selection and regulation of the mechanical properties of substrates or tissue microenvironments as a technique to model disease progression in tissues. Substrate mechanical properties include elasticity, which is varied dynamically. Also provided are methods and devices for screening for compounds useful for treating such diseases.
    Type: Application
    Filed: December 4, 2015
    Publication date: November 16, 2017
    Inventor: Adam Engler
  • Regulating stem cell differentiation by controlling matrix elasticity
    Publication number: 20070190646
    Abstract: Provided are methods for the selection and regulation of the mechanical properties of substrates or tissue microenvironments as a technique to regulate in vitro differentiation, cell shape and/or lineage commitment of anchorage-dependent cells, such as mesenchymal stem cells into, e.g., neurogenic-, myogenic-, and osteogenic-type cells. Substrate mechanical properties include elasticity, tension, adhesion, and myosin-based contractile mechanisms. Inhibitors can be introduced to further regulate differentiation.
    Type: Application
    Filed: February 10, 2006
    Publication date: August 16, 2007
    Inventors: Adam Engler, H. Sweeney, Dennis Discher