Patents by Inventor Adam Gehring

Adam Gehring has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HBV epitope reactive exogenous T cell receptor (TCR) and uses thereof
    Patent number: 10004801
    Abstract: There is provided at least one isolated cell comprising at least one HBV epitope-reactive exogenous T cell receptor and/or fragment thereof, and methods for producing them. In particular, there is provided polynucleotides, constructs and vectors encoding at least one HBV epitope-reactive exogenous T cell receptor for use in the treatment of Hepatitis B Virus (HBV) and Hepatocellular Carcinoma (HCC). The invention further provides kits and methods of detection of HBV and HCC.
    Type: Grant
    Filed: July 1, 2016
    Date of Patent: June 26, 2018
    Assignee: Agency for Science, Technology and Research
    Inventors: Antonio Bertoletti, Adam Gehring
  • HBV EPITOPE REACTIVE EXOGENOUS T CELL RECEPTOR (TCR) AND USES THEREOF
    Publication number: 20170202953
    Abstract: There is provided at least one isolated cell comprising at least one HBV epitope-reactive exogenous T cell receptor and/or fragment thereof, and methods for producing them. In particular, there is provided polynucleotides, constructs and vectors encoding at least one HBV epitope-reactive exogenous T cell receptor for use in the treatment of Hepatitis B Virus (HBV) and Hepatocellular Carcinoma (HCC). The invention further provides kits and methods of detection of HBV and HCC.
    Type: Application
    Filed: July 1, 2016
    Publication date: July 20, 2017
    Inventors: Antonio Bertoletti, Adam Gehring
  • HBV EPITOPE REACTIVE EXOGENOUS T CELL RECEPTOR (TCR) AND USES THEREOF
    Publication number: 20140134194
    Abstract: There is provided at least one isolated cell comprising at least one HBV epitope-reactive exogenous T cell receptor and/or fragment thereof, and methods for producing them. In particular, there is provided polynucleotides, constructs and vectors encoding at least one HBV epitope-reactive exogenous T cell receptor for use in the treatment of Hepatitis B Virus (HBV) and Hepatocellular Carcinoma (HCC). The invention further provides kits and methods of detection of HBV and HCC.
    Type: Application
    Filed: November 8, 2013
    Publication date: May 15, 2014
    Applicant: Agency for Science, Technology and Research
    Inventors: Antonio Bertoletti, Adam Gehring
  • T-cell having a T-cell receptor that recognizes epitope HBC18-27 of hepatitis B viral core antigen
    Patent number: 8603810
    Abstract: There is provided at least one isolated cell comprising at least one HBV epitope-reactive exogenous T cell receptor and/or fragment thereof, and methods for producing them. In particular, there is provided polynucleotides, constructs and vectors encoding at least one HBV epitope-reactive exogenous T cell receptor for use in the treatment of Hepatitis B Virus (HBV) and Hepatocellular Carcinoma (HCC). The invention further provides kits and methods of detection of HBV and HCC.
    Type: Grant
    Filed: May 7, 2009
    Date of Patent: December 10, 2013
    Assignee: Agency for Science, Technology and Research
    Inventors: Antonio Bertoletti, Adam Gehring
  • HBV EPITOPE REACTIVE EXOGENOUS T CELL RECEPTOR (TCR) AND USES THEREOF
    Publication number: 20110070208
    Abstract: There is provided at least one isolated cell comprising at least one HBV epitope-reactive exogenous T cell receptor and/or fragment thereof, and methods for producing them. In particular, there is provided polynucleotides, constructs and vectors encoding at least one HBV epitope-reactive exogenous T cell receptor for use in the treatment of Hepatitis B Virus (HBV) and Hepatocellular Carcinoma (HCC). The invention further provides kits and methods of detection of HBV and HCC.
    Type: Application
    Filed: May 7, 2009
    Publication date: March 24, 2011
    Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH
    Inventors: Antonio Bertoletti, Adam Gehring