Abstract: A ladder accessory device for insertion into an opening in a prior art ladder rung, wherein the ladder accessory device provides an elevated work environment that is out of the path of an individual ascending/descending the ladder. The accessory device is preferably comprised of a rung insert, a rung insert locking device, a support arm, a platform arm, and a platform arm locking device. The rung insert locking device permits the support arm to be rotated about the rung insert locking device, and the platform arm is likewise rotatable about the support arm. A wide arrange of accessories may also be removably attached to the platform to increase the overall usefulness of the device.

Abstract: There is disclosed a method and apparatus for enabling a location-aware mobile game reward system for encouraging real-world activity. The method includes sending an electronic notice of a reward available in a physical location to a mobile application operating on a mobile device, the mobile application having enhanced functionality available to be enabled by the reward and receiving location data indicating that the mobile application is operating online and currently at the physical location. The method further includes receiving interaction data indicating that a user of the mobile application has interacted with the mobile application in the physical location so as to obtain the reward and crediting the mobile application with the reward thereby enabling the enhanced functionality of the mobile application.

Abstract: A condom with a one-way sealing closure provides for an irreversible seal that once activated, prevents leakage of the condom contents after coitus, for sample collection or general disposal. The one-way sealing closure is provided by a cord that is disposed around the proximal circumference of the condom, and may be secured in an internal rolled channel or by guides attached to the outside wall of the condom. Additional features that may be included in the condom include various forms of one-way locking closures, visual and tactile guides, and a pull tab for operating the closure.

Abstract: The present invention is directed to substituted benzothiadiazinedioxide derivatives of formula I: or a pharmaceutically acceptable salt, stereoisomer or tautomer thereof, which are monoamine reuptake inhibitors, compositions containing these derivatives, and methods of their use for the prevention and treatment of conditions, including, inter alia, vasomotor symptoms, sexual dysfunction, gastrointestinal disorders and genitourinary disorder, depression disorders, endogenous behavioral disorders, cognitive disorders, diabetic neuropathy, pain, and other diseases or disorders.

Abstract: The present invention is directed to aryl sulfamide derivatives of formula I: or a pharmaceutically acceptable salt, stereoisomer or tautomer thereof, which are monoamine reuptake inhibitors, compositions containing these derivatives, and methods of their use for the prevention and treatment of conditions, including, inter alia, vasomotor symptoms, sexual dysfunction, gastrointestinal disorders and genitourinary disorder, depression disorders, endogenous behavioral disorders, cognitive disorders, diabetic neuropathy, pain, and other diseases or disorders.

Abstract: The present invention is directed to aryl sulfamide derivatives of formula I: or a pharmaceutically acceptable salt, stereoisomer or tautomer thereof, which are monoamine reuptake inhibitors, compositions containing these derivatives, and methods of their use for the prevention and treatment of conditions, including, inter alia, vasomotor symptoms, sexual dysfunction, gastrointestinal disorders and genitourinary disorder, depression disorders, endogenous behavioral disorders, cognitive disorders, diabetic neuropathy, pain, and other diseases or disorders.

Abstract: The present invention is directed to hydroxy-substituted aryl sulfamide derivatives of formula I: or a pharmaceutically acceptable salt, stereoisomer or tautomer thereof, which are monoamine reuptake inhibitors, compositions containing these derivatives, and methods of their use for the prevention and treatment of conditions, including, inter alia, vasomotor symptoms, sexual dysfunction, gastrointestinal disorders and genitourinary disorder, depression disorders, endogenous behavioral disorders, cognitive disorders, diabetic neuropathy, pain, and other diseases or disorders.

Abstract: The present invention is directed to cyclic sulfonamide derivatives of formula I: or a pharmaceutically acceptable salt thereof, which are monoamine reuptake inhibitors, compositions containing these derivatives, and methods of their use for the prevention and treatment of conditions, including, inter alia, vasomotor symptoms, sexual dysfunction, gastrointestinal disorders and genitourinary disorder, depression disorders, endogenous behaviorial disorder, cognitive disorder, diabetic neuropathy, pain, and other diseases or disorders.

Abstract: The present invention is directed to substituted benzothiadiazinedioxide derivatives of formula I: or a pharmaceutically acceptable salt, stereoisomer or tautomer thereof, which are monoamine reuptake inhibitors, compositions containing these derivatives, and methods of their use for the prevention and treatment of conditions, including, inter alia, vasomotor symptoms, sexual dysfunction, gastrointestinal disorders and genitourinary disorder, depression disorders, endogenous behavioral disorders, cognitive disorders, diabetic neuropathy, pain, and other diseases or disorders.

Abstract: The present invention is directed to aminoalkyl-substituted aryl sulfamide derivatives of formula I: or a pharmaceutically acceptable salt, stereoisomer or tautomer thereof, which are monoamine reuptake inhibitors, compositions containing these derivatives, and methods of their use for the prevention and treatment of conditions, including, inter alia, vasomotor symptoms, sexual dysfunction, gastrointestinal disorders and genitourinary disorder, depression disorders, endogenous behavioral disorders, cognitive disorders, diabetic neuropathy, pain, and other diseases or disorders.

Abstract: A system and method, as well as a computer-readable medium, are disclosed for providing collection subgroups within a main website that enable and facilitate networking for people having specific common interests or characteristics. Personal information provided by a user determines the user's automatic inclusion into a specific collection/category website. Computer generated routines supplied by the computer-readable medium of the present invention automatically fits users into one or more collections based on self-constructed concepts. In one embodiment, the present invention groups users into at least one collection and allow dynamic social-networking without the need for a user to pursue other's profiles to identify common interests or characteristics.