Abstract: A syringe for use with a powered injector to inject a fluid into a patient includes at least a first indicator positioned on the syringe at a predetermined axial position. The distance between a rearward surface of the first indicator and a predetermined position on the powered injector provides information about the syringe configuration. The first indicator can, for example, be a rear surface of the attachment flange. An injector system includes a powered injector having a drive member and at least one sensor for detecting energy. The injector system also includes a syringe having at least a first indicator positioned on the syringe at a predetermined axial position. The energy detected by the sensor is determined by the axial position of the indicator when the syringe is attached to the powered injector. The axial position of the indicator thereby provides information about the syringe configuration.