Patents by Inventor Adam J. Keseleski

Adam J. Keseleski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4235993
    Abstract: New intermediates, namely, N-benzylideneamphotericin B, and its methyl ester, are employed in a new process for preparing water-soluble salts of amphotericin B, methyl ester, such as amphotericin B, methyl ester aspartate.
    Type: Grant
    Filed: February 21, 1979
    Date of Patent: November 25, 1980
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Frank Sipos, Adam J. Keseleski
  • Patent number: 4041232
    Abstract: Amphotericin B methyl ester salts, such as salts formed by reaction with mono and dicarboxylic amino acids (such as aspartic acid, or glutamic acid or pyroglutamic acid), hydroxy carboxylic acids (such as lactic acid) and mono and dicarboxylic acids (such as acetic acid) are provided and have been found to be readily water-soluble and at least as stable and active as the parent ester compound.
    Type: Grant
    Filed: February 23, 1976
    Date of Patent: August 9, 1977
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Frank Sipos, Adam J. Keseleski