Abstract: The present disclosure relates to a dose indicator for a pressure-actuated metered dose inhaler (pMDI) device. In an embodiment, the dose indicator comprises a chassis element having a viewing portion, a display element located within the chassis element, a resilient deformable element, and an indexing element having an axis, translation of the indexing element along its axis from a first position to a second position causing deformation of the resilient deformable element in the same direction as translation of the indexing element resulting in generally greater displacement of portions of the resilient deformable element nearer to the axis relative to portions thereof further from the axis, the displacement of the portions of the resilient deformable element in the same direction as translation of the indexing element inducing indexing of the display element from a current position to a subsequent position relative to the viewing portion of the chassis element.

Abstract: A dose indicator or dose counter is disclosed which includes an indexable first display unit indexable about a first display axis, an indexable second display unit indexable about a second display axis, the second display axis being transverse to the first display axis, and a chassis comprising a chassis frame, a displacement portion comprising a drive means to engage the first display unit, and at least one hinge means directly or indirectly connecting the displacement portion and chassis frame. The drive means is preferably configured to index the dose indicator. The dose indicator/counter has a small number of components yet is effective, reliable and compact.

Abstract: An actuator for an inhaler, in particular a nasal actuator, is disclosed, the actuator comprising a body, a stem post and fixing means for fixing the stem post in the body. The body comprises a delivery passage for delivery of a medicament and a canister opening for insertion of a canister having a metering valve with a valve stem. The stem post comprises a stem socket for receiving the valve stem of a canister and comprises an orifice for discharging a medicament to the delivery passage. The stem post and body are adapted so they cooperate to define a transition chamber when the stem post is fixed in the body. Also disclosed is a method of forming an component for an actuator for an inhaler, and a method of assembling an actuator for an inhaler by inserting the stem post through the canister opening and into the body thereby.

Abstract: A metered dose dispensing valve for dispensing metered dose volumes of an aerosol formulation from an aerosol container comprising: •a first valve body (213) defining in part a metering chamber (212); •a compliant biasing member (215); •a valve stem (214) passing axially through the metering chamber, movable relative to the chamber between non-dispensing and dispensing positions, and biased from its dispensing position towards its non-dispensing position by the compliant biasing member; and •a second valve body (230) defining a non-compliant portion (991) and a compliant portion (992).

Abstract: Described are a dose counter (200) for use with an inhaler (5), and an actuator (20) for use with or as part of a dispenser. Further described is a dispenser containing a dose counter.

Abstract: The present disclosure relates to a dose indicator for a pressure-actuated metered dose inhaler (pMDI) device. In an embodiment, the dose indicator comprises a chassis element having a viewing portion, a display element located within the chassis element, a resilient deformable element, and an indexing element having an axis, translation of the indexing element along its axis from a first position to a second position causing deformation of the resilient deformable element in the same direction as translation of the indexing element resulting in generally greater displacement of portions of the resilient deformable element nearer to the axis relative to portions thereof further from the axis, the displacement of the portions of the resilient deformable element in the same direction as translation of the indexing element inducing indexing of the display element from a current position to a subsequent position relative to the viewing portion of the chassis element.

Abstract: A dispensing assembly for a container filled with a medicinal substance or formulation, the container being suitable for administering the medicinal substance or formulation via inhalation, buccal or sublingual delivery. The dispensing assembly includes a housing (1) defining a patient port through which, in use, the medicinal substance or formulation is dispensed. The dispensing assembly further includes a cap (3) that can be engaged with and disengaged from the patient port to close and open the patient port and an adhesive tape (10) having one portion (12) affixed to the housing and a second portion (11) affixed to the cap, such that when the cap is disengaged from the patient port, the cap is still connected to the housing.

Abstract: A dose counter for use in connection with a device adapted for metered dispensing of a medication is described. The dose counter has a first count indicator that has a first indicia bearing surface, with the first count indicator being rotatable about a first axis. The dose counter also has a second count indicator that has a second indicia bearing surface, with the second count indicator being rotatable about a second axis. The second axis is disposed at an obtuse angle with respect to the first axis, and the first and second indicia bearing surfaces align at a common viewing area to collectively present at least a portion of a medication dosage count.

Abstract: The present disclosure relates to a metered dose dispensing valve for dispensing metered volumes of an aerosol formulation from an aerosol container. The valves described herein are particularly suitable for use with metered dose inhalers for the oral delivery of medicaments. By combining the compliant biasing member and the second valve body into an integral single component it is possible to provide a desirable metered dose dispensing valve for use in inhalation devices or for use in the provision of canisters targeted for use in inhalation devices.

Abstract: A dose counter is described. The dose counter may be used, for instance, in a medical inhaler device.

Abstract: A dose counter for use in connection with a device adapted for metered dispensing of a medication is described. The dose counter has a first count indicator that has a first indicia bearing surface, with the first count indicator being rotatable about a first axis. The dose counter also has a second count indicator that has a second indicia bearing surface, with the second count indicator being rotatable about a second axis. The second axis is disposed at an obtuse angle with respect to the first axis, and the first and second indicia bearing surfaces align at a common viewing area to collectively present at least a portion of a medication dosage count.

Abstract: A dose counter for use in connection with a device adapted for metered dispensing of a medication is described. The dose counter has a first count indicator that has a first indicia bearing surface, with the first count indicator being rotatable about a first axis. The dose counter also has a second count indicator that has a second indicia bearing surface, with the second count indicator being rotatable about a second axis. The second axis is disposed at an obtuse angle with respect to the first axis, and the first and second indicia bearing surfaces align at a common viewing area to collectively present at least a portion of a medication dosage count.

Abstract: The present disclosure provides dry powder inhalers, containers for carrying a dose of dry powder medicament particles for dry powder inhalers, and a hinge that, while enjoying broader applicability, may be used in such inhalers.

Abstract: A dose counter is described. The dose counter may be used, for instance, in a medical inhaler device.

Abstract: Described are a dose counter (200) for use with an inhaler (5), and an actuator (20) for use with or as part of a dispenser. Further described is a dispenser containing a dose counter.

Abstract: This application discloses a dose counter for use in connection with a device adapted for metered dispensing of a medication. The dose counter has a first count indicator that has a first indicia bearing surface, with the first count indicator being rotatable about a first axis. The dose counter also has a second count indicator that has a second indicia bearing surface, with the second count indicator being rotatable about a second axis. The second axis is disposed at an obtuse angle with respect to the first axis, and the first and second indicia bearing surfaces align at a common viewing area to collectively present at least a portion of a medication dosage count.