Patents by Inventor Adam James Donoghue

Adam James Donoghue has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MATERIALS AND METHODS FOR TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS
    Publication number: 20230392134
    Abstract: The present application provides materials and methods for treating a patient with Amyotrophic Lateral Sclerosis (ALS). In addition, the present application provides materials and methods for (1) modifying the transcription start site of exon1a to render the transcription start site non-functioning, (2) deleting the transcription site of exon1a, (3) deleting exon1a, or (4) deleting of the expanded hexanucleotide repeat within or near the C9ORF72 gene, or any combinations of (1)-(4), above in a cell by genome editing.
    Type: Application
    Filed: September 29, 2021
    Publication date: December 7, 2023
    Applicant: CRISPR THERAPEUTICS AG
    Inventors: Hari Kumar Padmanabhan, Adam James Donoghue
  • MATERIALS AND METHODS FOR TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS
    Publication number: 20220290136
    Abstract: The present application provides materials and methods for treating a patient with Amyotrophic Lateral Sclerosis (ALS). In addition, the present application provides materials and methods for (1) modifying the transcription start site of exon1a to render the transcription start site non-functioning, (2) deleting the transcription site of exon1a, (3) deleting exon1a, or (4) deleting of the expanded hexanucleotide repeat within or near the C9ORF72 gene, or any combinations of (1)-(4), above in a cell by genome editing.
    Type: Application
    Filed: September 29, 2021
    Publication date: September 15, 2022
    Inventors: Hari Kumar Padmanabhan, Adam James Donoghue