Patents by Inventor Adam Joseph Kreuzman

Adam Joseph Kreuzman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Lipoglycopeptide antibiotics
    Patent number: 6951840
    Abstract: Provided are novel lipoglycopeptides exhibiting bacterial signal peptidase inhibitory activity. Also provided are actinomycete strains that produce these lipoglycopeptides, methods of producing such lipoglycopeptides by culturing these strains, pharmaceutical compositions comprising these lipoglycopeptides, and methods of treating bacterial infections comprising contacting bacteria susceptible to treatment with the present bacterial signal peptidase inhibitor lipoglycopeptides. These lipoglycopeptides are useful in human and veterinary medicine.
    Type: Grant
    Filed: August 14, 2002
    Date of Patent: October 4, 2005
    Assignee: Eli Lilly and Company
    Inventors: Matthew David Belvo, Adam Joseph Kreuzman, Palaniappan Kulanthaivel, Sheng-Bin Peng, Tim Allen Smitka
  • Novel lipoglycopeptide antibiotics
    Publication number: 20030130172
    Abstract: Provided are novel lipoglycopeptides exhibiting bacterial signal peptidase inhibitory activity. Also provided are actinomycete strains that produce these lipoglycopeptides, methods of producing such lipoglycopeptides by culturing these strains, pharmaceutical compositions comprising these lipoglycopeptides, and methods of treating bacterial infections comprising contacting bacteria susceptible to treatment with the present bacterial signal peptidase inhibitor lipoglycopeptides. These lipoglycopeptides are useful in human and veterinary medicine.
    Type: Application
    Filed: August 14, 2002
    Publication date: July 10, 2003
    Inventors: Matthew David Belvo, Adam Joseph Kreuzman, Palaniappan Kulanthaivel, Sheng-Bin Peng, Tim Allen Smitka
  • Teicoplanin deacylation process and product
    Patent number: 5936074
    Abstract: The present invention is directed to deacyl teicoplanin, and to a process for preparing deacyl teicoplanin by reacting teicoplanin with ECB deacylase. Deacyl teicoplanin can be alkylated to produce compounds useful for their antibacterial activity.
    Type: Grant
    Filed: April 1, 1998
    Date of Patent: August 10, 1999
    Assignee: Eli Lilly and Company
    Inventors: Barbara Shreve Briggs, Robin David Grey Cooper, Adam Joseph Kreuzman, Milton Joseph Zmijewski, Jr.