Abstract: Electron generation apparatuses are disclosed that can include a power source coupled to a first electrode, and a switch between the power source and the first electrode. Mass spectrometry instruments are disclosed that can include a power source coupled to a first electrode, and a switch between the power source and the first electrode. Methods of generating electrons are provided that can include generating different voltage differentials across a cell, with at least one of the voltage differentials generating electrons from gaseous material, and discharging at least some of the electrons from the cell. Mass spectrometry methods are also provided that can include providing sample proximate a glow discharge ionization source, and generating a pulse of electrons from the ionization source according to an ionization parameter to ionize at least a portion of the sample.