Patents by Inventor Adam Kenneth Charnley

Adam Kenneth Charnley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11365190
    Abstract: Disclosed are compounds having the formula: wherein q, r, s, A, B, C, RA1, RA2, RB1, RB2, RC1, RC2, R3, R4, R5, R6, R14, R15, R16, and R17, are as defined herein, or a tautomer thereof, or a salt, particularly a pharmaceutically acceptable salt, thereof.
    Type: Grant
    Filed: January 25, 2021
    Date of Patent: June 21, 2022
    Assignee: GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED
    Inventors: Adam Kenneth Charnley, Gren Z. Wang, Joseph J. Romano
  • Publication number: 20210238172
    Abstract: The invention relates to combinations comprising a compound of the formula: or a salt thereof; and one or more additional pharmaceutically agents active against HIV, and methods of using the same.
    Type: Application
    Filed: October 4, 2018
    Publication date: August 5, 2021
    Applicant: GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED
    Inventors: Adam Kenneth CHARNLEY, Michael Gerard DARCY, Jason W. DODSON, Xiaoyang DONG, David FAVRE, Terry Vincent HUGHES, Jianxing KANG, Lara Kathryn LEISTER, Yuehu LI, Yiqian LIAN, John F. MEHLMANN, Neysa NEVINS, Joshi M. RAMANJULU, Joseph J. ROMANO, Gren Z. WANG, Guosen YE, Daohua ZHANG
  • Publication number: 20210139473
    Abstract: Disclosed are compounds having the formula: wherein q, r, s, A, B, C, RA1, RA2, RB1, RB2, RC1, RC2, R3, R4, R5, R6, R14, R15, R16, and R17, are as defined herein, or a tautomer thereof, or a salt, particularly a pharmaceutically acceptable salt, thereof.
    Type: Application
    Filed: January 25, 2021
    Publication date: May 13, 2021
    Inventors: Adam Kenneth CHARNLEY, Gren Z. Wang, Joseph J. Romano
  • Patent number: 10975287
    Abstract: Disclosed are compounds having the formula: wherein Ra, R1, R2, R3, R4, R5, R6, R7, and R8, are as defined herein, or a salt, particularly a pharmaceutically acceptable salt, thereof.
    Type: Grant
    Filed: April 5, 2017
    Date of Patent: April 13, 2021
    Inventors: Adam Kenneth Charnley, Michael G. Darcy, Jason W. Dodson, Terry V. Hughes, Yue Li, Yiqian Lian, Neysa Nevins, Joshi M. Ramanjulu
  • Publication number: 20200325126
    Abstract: Disclosed are compounds having the formula: wherein Ra, R1, R2, R3, R4, R5, R6, R7, and R8, are as defined herein, or a salt, particularly a pharmaceutically acceptable salt, thereof.
    Type: Application
    Filed: April 5, 2017
    Publication date: October 15, 2020
    Applicant: GlaxoSmithKline Intellectual Property Development Limited
    Inventors: Adam Kenneth CHARNLEY, Robert Clifford Roback, Robert D. Gilbertson, Hakim Boukhalfa, Scott w. Imbus
  • Patent number: 10220030
    Abstract: Disclosed are compounds having the formula: wherein R1, R2, R3 and Z are as defined herein, and methods of making and using the same.
    Type: Grant
    Filed: November 14, 2017
    Date of Patent: March 5, 2019
    Assignee: GlaxoSmithKline Intellectual Property Development Limited
    Inventors: Michael Jonathan Bury, Linda N. Casillas, Adam Kenneth Charnley, Pamela A. Haile, Robert W. Marquis, Jr., John F. Mehlmann, Joseph J. Romano, Robert R. Singhaus, Jr., Gren Z. Wang
  • Publication number: 20180085365
    Abstract: Disclosed are compounds having the formula: wherein R1, R2, R3 and Z are as defined herein, and methods of making and using the same.
    Type: Application
    Filed: November 14, 2017
    Publication date: March 29, 2018
    Inventors: Michael Jonathan BURY, Linda N. CASILLAS, Adam Kenneth CHARNLEY, Pamela A. HAILE, Robert W. MARQUIS, JR., John F. MEHLMANN, Joseph J. ROMANO, Robert R. SINGHAUS, JR., Gren Z. WANG
  • Patent number: 9650364
    Abstract: Disclosed are compounds that are inhibitors of RIP2 kinase and methods of making and using the same.
    Type: Grant
    Filed: February 19, 2014
    Date of Patent: May 16, 2017
    Assignee: GlaxoSmithKline Intellectual Property Development Limted
    Inventors: Linda N. Casillas, Adam Kenneth Charnley, Xiaoyang Dong, Pamela A. Haile, Michael P. Demartino, John F. Mehlmann
  • Publication number: 20170128437
    Abstract: Disclosed are compounds having the formula: wherein R1, R2, R3 and Z are as defined herein, and methods of making and using the same.
    Type: Application
    Filed: January 24, 2017
    Publication date: May 11, 2017
    Inventors: Michael Jonathan BURY, Linda N. CASILLAS, Adam Kenneth CHARNLEY, Pamela A. HAILE, Robert W. MARQUIS, JR., John F. MEHLMANN, Joseph J. ROMANO, Robert R. SINGHAUS, JR., Gren Z. WANG
  • Patent number: 9604963
    Abstract: Disclosed are compounds having the formula: wherein R1, R2, R3 and Z are as defined herein, and methods of making and using the same.
    Type: Grant
    Filed: March 2, 2012
    Date of Patent: March 28, 2017
    Assignee: GlaxoSmithKline Intellectual Property Development Limited
    Inventors: Michael Jonathan Bury, Linda N. Casillas, Adam Kenneth Charnley, Pamela A. Haile, Robert W. Marquis, Jr., John F. Mehlmann, Joseph J. Romano, Robert R. Singhaus, Jr., Gren Z. Wang
  • Publication number: 20160060222
    Abstract: Disclosed are quinoline compounds having the formula: wherein R1, R2 and A are as defined herein, and methods of making and using the same.
    Type: Application
    Filed: November 6, 2015
    Publication date: March 3, 2016
    Inventors: Michael Jonathan BURY, Linda N. CASILLAS, Adam Kenneth CHARNLEY, Michael P. DeMARTINO, Xiaoyang DONG, Patrick EIDAM, Pamela A. HAILE, Philip Anthony HARRIS, Ami Lakdawala SHAH, Bryan W. KING, Robert W. MARQUIS, JR., John F. MEHLMANN, Joseph J. ROMANO, Clark A. SEHON
  • Publication number: 20160060249
    Abstract: Disclosed are compounds having the formula: wherein R1, R2, R3, R4 and R5 are as defined herein, and methods of making and using the same.
    Type: Application
    Filed: November 5, 2015
    Publication date: March 3, 2016
    Inventors: Linda N. CASILLAS, Adam Kenneth Charnley, Pamela A. Haile, Terry Vincent Hughes, Robert W. Marquis, JR., John F. Mehlmann, Michael Reilly, Joseph J. Romano, Robert R. Singhaus, JR.
  • Publication number: 20150361069
    Abstract: Disclosed are compounds that are inhibitors of RIP2 kinase and methods of making and using the same.
    Type: Application
    Filed: February 19, 2014
    Publication date: December 17, 2015
    Inventors: Linda N. CASILLAS, Adam Kenneth CHARNLEY, Xiaoyang DONG, Pamela A. HAILE, Michael P. DEMARTINO, John F. MEHLMANN
  • Publication number: 20140256949
    Abstract: Disclosed are compounds having the formula: wherein R1, R2, R3, R4 and R5 are as defined herein, and methods of making and using the same.
    Type: Application
    Filed: May 21, 2014
    Publication date: September 11, 2014
    Applicant: GlaxoSmithKline Intellectual Property Development Limited
    Inventors: Linda N. CASILLAS, Adam Kenneth Charnley, Pamela A. Haile, Terry Vincent Hughes, Robert W. Marquis, JR., John F. Mehlmann, Michael Reilly, Joseph J. Romano, Robert R. Singhaus, JR.
  • Publication number: 20130345258
    Abstract: Disclosed are compounds having the formula: wherein R1, R2, R3 and Z are as defined herein, and methods of making and using the same.
    Type: Application
    Filed: March 2, 2012
    Publication date: December 26, 2013
    Applicant: Glaxosmithline LLC
    Inventors: Michael Jonathan Bury, Linda N. Casillas, Adam Kenneth Charnley, Pamela A. Haile, Robert W. Marquis, JR., John F. Mehlmann, Joseph J. Romano, Robert R. Singhaus, JR., Gren Z. Wang
  • Publication number: 20130053375
    Abstract: Disclosed are quinoline compounds having the formula: wherein R1, R2 and A are as defined herein, and methods of making and using the same.
    Type: Application
    Filed: May 6, 2011
    Publication date: February 28, 2013
    Inventors: Michael Jonathan Bury, Linda N. Casillas, Adam Kenneth Charnley, Michael P. DeMartino, Xiaoyang Dong, Patrick Eidam, Pamela A. Haile, Philip Anthony Harris, Ami Lakdawala Shah, Bryan W. King, Robert W. Marquis, JR., John F. Mehlmann, Joseph J. Romano, Clark A. Sehon
  • Publication number: 20130023532
    Abstract: Disclosed are compounds having the formula: or a salt thereof, wherein A, n, R1, R1A, and R2 are as defined herein, and methods of making and using the same.
    Type: Application
    Filed: March 26, 2011
    Publication date: January 24, 2013
    Inventors: Linda N. Casillas, Subhas J. Chakravorty, Adam Kenneth Charnley, Pamela A. Haile, Terry Vincent Hughes, Jae U. Jeong, Jianxing Kang, Ami Lakdawala Shah, Lara Kathryn Leister, Robert W. Marquis, JR., Nathan Andrew Miller, Daniel J. Price, Clark A. Sehon, Gren Z. Wang, Daohua Zhang, Patrick Eidam
  • Publication number: 20120041024
    Abstract: Disclosed are compounds having the formula: wherein R1, R2, R3, R4 and R5 are as defined herein, and methods of making and using the same.
    Type: Application
    Filed: August 10, 2011
    Publication date: February 16, 2012
    Inventors: Adam Kenneth Charnley, Pamela A. Haile, Terry Vincent Hughes