Patents by Inventor Adam M. McCoy

Adam M. McCoy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND HYDROGEL COMPOSITIONS FOR PARTITIONING BIOLOGICAL SAMPLES
    Publication number: 20230383332
    Abstract: Methods of making and forming partitions in nanovials are provided.
    Type: Application
    Filed: May 30, 2023
    Publication date: November 30, 2023
    Inventors: Ronald LEBOFSKY, Josh SHINOFF, Adam M. McCOY, Man CHENG
  • RNA amplification methods
    Patent number: 11021735
    Abstract: Methods of detecting and amplifying short RNAs are provided.
    Type: Grant
    Filed: June 15, 2018
    Date of Patent: June 1, 2021
    Assignee: Bio-Rad Laboratories, Inc.
    Inventors: Man Cheng, Xiao-Song Gong, Yan Wang, Adam M. McCoy
  • RNA AMPLIFICATION METHODS
    Publication number: 20180305739
    Abstract: Methods of detecting and amplifying short RNAs are provided.
    Type: Application
    Filed: June 15, 2018
    Publication date: October 25, 2018
    Inventors: Man Cheng, Xiao-Song Gong, Yan Wang, Adam M. McCoy
  • RNA amplification methods
    Patent number: 10072285
    Abstract: Methods of detecting and amplifying short RNAs are provided.
    Type: Grant
    Filed: August 17, 2015
    Date of Patent: September 11, 2018
    Assignee: Bio-Rad Laboratories, Inc.
    Inventors: Man Cheng, Xiao-Song Gong, Yan Wang, Adam M. McCoy
  • Digital assays with associated targets
    Patent number: 9856525
    Abstract: System, including methods, apparatus, and compositions, for performing a digital assay with associated targets. In some embodiments, the assay of associated targets in partitions may lower the limit of detection (LOD) or otherwise increase assay sensitivity, accuracy, and/or specificity. The targets may represent spaced or overlapping regions of the same template and/or each may represent a region from a different complementary strand of the same template. In some embodiments, the associated targets may be provided by a type of biological particle, and the target content of partitions may be used to identify and quantify the type of biological particle in a sample.
    Type: Grant
    Filed: March 17, 2014
    Date of Patent: January 2, 2018
    Assignee: Bio-Rad Laboratories, Inc.
    Inventors: Adam M. McCoy, Niels Klitgord
  • Affinity-based partition assay for detection of target molecules
    Patent number: 9850515
    Abstract: The present invention provides methods of detecting a target molecule in a sample comprising incubating the sample with two or more detectably labeled probes, partitioning the sample into multiple partitions, and detecting the presence of the two or more probes in the same partition.
    Type: Grant
    Filed: February 5, 2014
    Date of Patent: December 26, 2017
    Assignee: Bio-Rad Laboratories, Inc.
    Inventors: Adam M. McCoy, Svilen Tzonev, Frank Hsiung
  • Repetitive reverse transcription partition assay
    Patent number: 9745571
    Abstract: Methods, compositions, and kits are provided for quantifying RNA molecules in a partitioned sample via multiple reverse transcription reactions.
    Type: Grant
    Filed: March 7, 2014
    Date of Patent: August 29, 2017
    Assignee: Bio-Rad Laboratories, Inc.
    Inventor: Adam M. McCoy
  • MULTIPLEXED DIGITAL ASSAYS WITH COMBINATORIAL USE OF SIGNALS
    Publication number: 20160108464
    Abstract: System, including methods, apparatus, and compositions, for performing a multiplexed digital assay on a greater number of targets through combinatorial use of signals.
    Type: Application
    Filed: December 28, 2015
    Publication date: April 21, 2016
    Inventors: Serge Saxonov, Simant Dube, Benjamin J. Hindson, Adam M. McCoy
  • RNA AMPLIFICATION METHODS
    Publication number: 20160053305
    Abstract: Methods of detecting and amplifying short RNAs are provided.
    Type: Application
    Filed: August 17, 2015
    Publication date: February 25, 2016
    Inventors: Man Cheng, Xiao-Song Gong, Yan Wang, Adam M. McCoy
  • Multiplexed digital assays with combinatorial use of signals
    Patent number: 9222128
    Abstract: System, including methods, apparatus, and compositions, for performing a multiplexed digital assay on a greater number of targets through combinatorial use of signals.
    Type: Grant
    Filed: March 19, 2012
    Date of Patent: December 29, 2015
    Assignee: Bio-Rad Laboratories, Inc.
    Inventors: Serge Saxonov, Simant Dube, Benjamin J. Hindson, Adam M. McCoy
  • DIGITAL ASSAYS WITH ASSOCIATED TARGETS
    Publication number: 20140274786
    Abstract: System, including methods, apparatus, and compositions, for performing a digital assay with associated targets. In some embodiments, the assay of associated targets in partitions may lower the limit of detection (LOD) or otherwise increase assay sensitivity, accuracy, and/or specificity. The targets may represent spaced or overlapping regions of the same template and/or each may represent a region from a different complementary strand of the same template. In some embodiments, the associated targets may be provided by a type of biological particle, and the target content of partitions may be used to identify and quantify the type of biological particle in a sample.
    Type: Application
    Filed: March 17, 2014
    Publication date: September 18, 2014
    Inventors: Adam M. McCoy, Niels Klitgord
  • REPETITIVE REVERSE TRANSCRIPTION PARTITION ASSAY
    Publication number: 20140256585
    Abstract: Methods, compositions, and kits are provided for quantifying RNA molecules in a partitioned sample via multiple reverse transcription reactions.
    Type: Application
    Filed: March 7, 2014
    Publication date: September 11, 2014
    Applicant: Bio-Rad Laboratories, Inc.
    Inventor: Adam M. McCoy
  • AFFINITY-BASED PARTITION ASSAY FOR DETECTION OF TARGET MOLECULES
    Publication number: 20140228239
    Abstract: The present invention provides methods of detecting a target molecule in a sample comprising incubating the sample with two or more detectably labeled probes, partitioning the sample into multiple partitions, and detecting the presence of the two or more probes in the same partition.
    Type: Application
    Filed: February 5, 2014
    Publication date: August 14, 2014
    Applicant: Bio-Rad Laboratories, Inc.
    Inventors: Adam M. McCoy, Svilen Tzonev, Frank Hsiung
  • MULTIPLEXED DIGITAL ASSAYS WITH COMBINATORIAL USE OF SIGNALS
    Publication number: 20120329664
    Abstract: System, including methods, apparatus, and compositions, for performing a multiplexed digital assay on a greater number of targets through combinatorial use of signals.
    Type: Application
    Filed: March 19, 2012
    Publication date: December 27, 2012
    Applicant: BIO-RAD LABORATORIES, INC.
    Inventors: Serge Saxonov, Simant Dube, Benjamin J. Hindson, Adam M. McCoy