Abstract: In a modular medicament delivery system, a dispenser housing has a support block with a well and an orifice communicating with the well. A first container assembly includes a valve stem shaped to be received by the well in the support block. The first container assembly has a first exterior shape. A second container assembly includes a valve stem shaped to be received by the well in the support block. The second container assembly has a second exterior shape that is different than the first exterior shape. An insert member is adapted for mounting to the dispenser housing in the cavity and defines an interior space shaped to receive the second exterior shape of the second container. Methods of assembling the system, a system kit and a device are also provided. A medication delivery device includes first and second end pieces and a collapsible chamber disposed therebetween.

Abstract: An oscillating positive respiratory pressure apparatus and a method of performing oscillating positive respiratory pressure therapy. The apparatus includes a housing having an interior chamber, a chamber inlet, a chamber outlet, an exhalation flow path defined between the inlet and the outlet, and a restrictor member rotatably mounted within the interior chamber. The restrictor member has an axis of rotation that is substantially perpendicular to the flow path at the inlet, and includes at least one blocking segment. Rotation of the restrictor member moves the at least one blocking segment between an open position and a closed position. Respiratory pressure at the chamber inlet oscillates between a minimum when the at least one blocking segment is in the open position and a maximum when the at least one blocking segment is in the closed position. By exhaling into the apparatus, oscillating positive expiratory pressure therapy is administered.

Abstract: In a modular medicament delivery system, a dispenser housing has a support block with a well and an orifice communicating with the well. A first container assembly includes a valve stem shaped to be received by the well in the support block. The first container assembly has a first exterior shape. A second container assembly includes a valve stem shaped to be received by the well in the support block. The second container assembly has a second exterior shape that is different than the first exterior shape. An insert member is adapted for mounting to the dispenser housing in the cavity and defines an interior space shaped to receive the second exterior shape of the second container. Methods of assembling the system, a system kit and a device are also provided. A medication delivery device includes first and second end pieces and a collapsible chamber disposed therebetween.

Abstract: An oscillating positive respiratory pressure apparatus and a method of performing oscillating positive respiratory pressure therapy. The apparatus includes a housing having an interior chamber, a chamber inlet, a chamber outlet, an exhalation flow path defined between the inlet and the outlet, and a restrictor member rotatably mounted within the interior chamber. The restrictor member has an axis of rotation that is substantially perpendicular to the flow path at the inlet, and includes at least one blocking segment. Rotation of the restrictor member moves the at least one blocking segment between an open position and a closed position. Respiratory pressure at the chamber inlet oscillates between a minimum when the at least one blocking segment is in the open position and a maximum when the at least one blocking segment is in the closed position. By exhaling into the apparatus, oscillating positive expiratory pressure therapy is administered.

Abstract: An oscillating positive expiratory pressure device comprising a housing enclosing at least one chamber, a chamber inlet configured to receive exhaled air into the at least one chamber, and a chamber outlet configured to permit exhaled air to exit the at least one chamber. A channel is positioned in an exhalation flow path between the chamber inlet and the chamber outlet, with the channel being moveably connected to a chamber of the at least one chamber. An air flow regulator is moveable with respect to the channel between a first position, where the flow of air through the channel is restricted and a second position, where the flow of air through the channel is less restricted, the air flow regulator being configured to repeatedly move between the first position and the second position in response to a flow of exhaled air.

Abstract: A respiratory treatment device comprising at least one chamber, a chamber inlet configured to receive exhaled air into the at least one chamber, at least one chamber outlet configured to permit exhaled air to exit the at least one chamber, and an exhalation flow path defined between the chamber inlet and the at least one chamber outlet. A restrictor member positioned in the exhalation flow path is moveable between a closed position, where a flow of exhaled air along the exhalation flow path is restricted, and an open position, where the flow of exhaled air along the exhalation flow path is less restricted. A vane in fluid communication with the exhalation flow path is operatively connected to the restrictor member and is configured to reciprocate between a first position and a second position in response to the flow of exhaled air along the exhalation flow path.

Abstract: A ventilator assembly includes a housing defining an inhalation interior space and an exhalation interior space separate from the inhalation interior space. A ventilator port is positioned at a first location of the housing and defines a first passageway in communication with the inhalation interior space and the exhalation interior space. A patient port is positioned at a second location of the housing and defines a second passageway in communication with the inhalation interior space and the exhalation interior space. A one-way inhalation valve permits one-way flow from the ventilator port to the patient port through the inhalation interior space and a one-way exhalation valve permits one-way flow from the patient port to the ventilator port through the exhalation interior space. A receptacle is in communication with the inhalation interior space and is operative to receive a container comprising an aerosolized medication.

Abstract: An adapter for use in a breathing circuit including a housing with a conduit having a ventilator port adapted to be coupled to a breathing circuit and a patient port adapted to communicate with a patient interface. A medicament container receptacle communicates with the conduit between the ventilator port and the patient port. The receptacle includes a support block having a well shaped to receive a valve stem extending from a container of medicament and an actuator finger extending upwardly in the receptacle adjacent the support block. The actuator finger is adapted to actuate a dose counter coupled to the container.

Abstract: Ventilator circuit aerosol delivery systems used to administer medication to a patient are disclosed. In one implementation, a metered dose inhaler (“MDI”) ventilator assembly may include a housing that defines an interior space, an inhalation port that defines an inhalation passageway in communication with the interior space, an exhalation port that defines an exhalation passageway in communication with the interior space, a patient port that defines a patient passageway in communication with the interior space, and a MDI receptacle positioned on the housing and in communication with the interior space. The MDI receptacle is operative to receive a MDI container and dispense an aerosolized medication within the MID container into the interior space so that during inhalation, an inhalation flow including the aerosolized medication may flow through the inhalation port, the interior space, and the patient port.

Abstract: A respiratory device comprising a housing enclosing a chamber and an orientation indicator moveable with respect to the housing between a first position indicative of an orientation of the housing predetermined to be suitable for operation of the respiratory device, and a second position indicative of an orientation of the respiratory device predetermined to be less suitable for operation of the respiratory device. The orientation indicator is positioned in a location on the respiratory device visible to a user during the operation of the respiratory device.

Abstract: In a modular medicament delivery system, a dispenser housing has a support block with a well and an orifice communicating with the well. A first container assembly includes a valve stem shaped to be received by the well in the support block. The first container assembly has a first exterior shape. A second container assembly includes a valve stem shaped to be received by the well in the support block. The second container assembly has a second exterior shape that is different than the first exterior shape. An insert member is adapted for mounting to the dispenser housing in the cavity and defines an interior space shaped to receive the second exterior shape of the second container. Methods of assembling the system, a system kit and a device are also provided. A medication delivery device includes first and second end pieces and a collapsible chamber disposed therebetween.

Abstract: Ventilator circuit aerosol delivery systems used to administer medication to a patient are disclosed. In one implementation, a metered dose inhaler (“MDI”) ventilator assembly may include a housing that defines an interior space, an inhalation port that defines an inhalation passageway in communication with the interior space, an exhalation port that defines an exhalation passageway in communication with the interior space, a patient port that defines a patient passageway in communication with the interior space, and a MDI receptacle positioned on the housing and in communication with the interior space. The MDI receptacle is operative to receive a MDI container and dispense an aerosolized medication within the MID container into the interior space so that during inhalation, an inhalation flow including the aerosolized medication may flow through the inhalation port, the interior space, and the patient port.

Abstract: Novel N-phenyl-1,1,1-trifluoromethanesulfonamide compounds useful for controlling endo and/or ectoparasites in the environment are provided, together with methods of making the same, and methods of using the inventive compounds to treat parasite infestations in vivo and ex vivo.

Abstract: Methods for treating an animal for endo and/or ecto parasite infestation and/or for protecting an animal from endo and/or ecto parasite infestation using N-phenyl-1,1,1-trifluoromethanesulfonamide compounds are provided, together with methods of making the same compounds, and methods of using the same compounds to treat parasite infestations in vivo or ex vivo. N-phenyl-1,1,1-trifluoromethanesulfonamides are also provided.

Abstract: A bit retention apparatus for the use of retrieving the hammer bit in cases of shankage. The apparatus incorporates a dual sleeve design that fits over the chuck and the extended head section of the hammer bit. The first, “inner” sleeve has two or more ring pieces that fit onto the chuck and have the retention ring fitted into the lower section of the sleeve. The second, “outer” sleeve fits onto the chuck over the inner sleeve to provide protect to the inner sleeve while pulling the shanked bit out of the well bore. Attachment to the bit is accomplished by collars, knobs, or threads on the interior of the sleeves that correspond with holding bands, retention rings, or threads on the bit and chuck.

Abstract: Novel trifluoromethanesulfonanilide oxime ether compounds useful for controlling endo and/or ectoparasites in the environment are provided, together with methods of making the same, and methods of using the inventive compounds to treat parasite infestations in vivo or ex vivo.

Abstract: A percussion drill bit is provided that has at least two different pluralities of inserts extending from the bit head to better match the conditions seen on the bit head during drilling. The preferred embodiment has a plurality of large inserts with a polycrystalline diamond layer located at least in the gage row and a plurality of smaller inserts located at least in the inner rows.