Patents by Inventor Adam N. Harris

Adam N. Harris has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS FOR SEAMLESS CLONING OF NUCLEIC ACID MOLECULES
    Publication number: 20120149069
    Abstract: The present invention is in the fields of biotechnology and molecular biology. More particularly, the present invention relates to cloning or subcloning one or more nucleic acid molecules comprising one or more type IIs restriction enzyme recognition sites. The present invention also embodies cloning such nucleic acid molecules using recombinational cloning methods such as those employing recombination sites and recombination proteins. The present invention also relates to nucleic acid molecules (including RNA and iRNA), as well as proteins, expressed from host cells produced using the methods of the present invention.
    Type: Application
    Filed: February 21, 2012
    Publication date: June 14, 2012
    Applicant: LIFE TECHNOLOGIES CORPORATION
    Inventors: Jonathan D. Chesnut, Knut R. Madden, Miroslav Dudas, Louis Leong, Adam N. Harris
  • COMPOSITIONS AND METHODS FOR PREPARING SHORT RNA MOLECULES AND OTHER NUCLEIC ACIDS
    Publication number: 20120108804
    Abstract: The invention provides methods of preparing nucleic acids, such as RNA molecules, of a defined size or range of sizes. The invention provides compositions, methods and kits for use in the production and preparation of small RNA molecules (including without limitation micro-RNA, siRNA, d-siRNA and e-siRNA) and other nucleic acids of various sizes.
    Type: Application
    Filed: July 25, 2011
    Publication date: May 3, 2012
    Applicant: LIFE TECHNOLOGIES CORPORATION
    Inventors: Knut R. Madden, Adam N. Harris, Karl H. Hecker, Byung-in Lee
  • METHODS AND COMPOSITIONS FOR SEAMLESS CLONING OF NUCLEIC ACID MOLECULES
    Publication number: 20110046201
    Abstract: The present invention is in the fields of biotechnology and molecular biology. More particularly, the present invention relates to cloning or subcloning one or more nucleic acid molecules comprising one or more type IIs restriction enzyme recognition sites. The present invention also embodies cloning such nucleic acid molecules using recombinational cloning methods such as those employing recombination sites and recombination proteins. The present invention also relates to nucleic acid molecules (including RNA and iRNA), as well as proteins, expressed from host cells produced using the methods of the present invention.
    Type: Application
    Filed: April 30, 2008
    Publication date: February 24, 2011
    Applicant: INVITROGEN CORPORATION
    Inventors: Jonathan D. Chesnut, Knut R. Madden, Miroslav Dudas, Louis Leong, Adam N. Harris
  • Method for the in vitro synthesis of short double stranded RNAs
    Patent number: 7659391
    Abstract: The present invention relates to the field of synthesis of short double-stranded RNAs. An in vitro transcription method using bacteriophage polymerases and target sequence-specific single-stranded DNA oligonucleotides as templates is disclosed. The present invention finds particularly advantageous use in the synthesis of short interfering RNAs (siRNAs) that have been shown to function as key intermediates in triggering sequence-specific RNA degradation during posttranscriptional gene silencing in plants and RNA interference in invertebrates and vertebrate systems.
    Type: Grant
    Filed: October 30, 2002
    Date of Patent: February 9, 2010
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Marianne Denise De Backer, Adam N. Harris
  • COMPOSITIONS AND METHODS FOR PREPARING SHORT RNA MOLECULES AND OTHER NUCLEIC ACIDS
    Publication number: 20090197307
    Abstract: The invention provides methods of preparing nucleic acids, such as RNA molecules, of a defined size or range of sizes. The invention provides compositions, methods and kits for use in the production and preparation of small RNA molecules (including without limitation micro-RNA, siRNA, d-siRNA and e-siRNA) and other nucleic acids of various sizes.
    Type: Application
    Filed: August 11, 2008
    Publication date: August 6, 2009
    Applicant: INVITROGEN CORPORATION
    Inventors: Knut R. Madden, Adam N. Harris, Karl H. Hecker, Byung-in Lee
  • Method for the in vitro synthesis of short double stranded rnas
    Publication number: 20040259097
    Abstract: The present invention relates to the field of synthesis of short double-stranded RNAs. An in vitro transcription method using bacteriophage polymerases and target sequence-specific single-stranded DNA oligonucleotides as templates is disclosed. The present invention finds particularly advantageous use in the synthesis of short interfering RNAs (siRNAs) that have been shown to function as key intermediates in triggering sequence-specific RNA degradation during posttranscriptional gene silencing in plants and RNA interference in invertebrates and vertebrate systems.
    Type: Application
    Filed: May 4, 2004
    Publication date: December 23, 2004
    Inventors: Marianne Denise De Backer, Adam N Harris