Abstract: The disclosure provides TNF-like ligand 1a (TL1a)-binding proteins comprising an antigen binding domain of an antibody which binds specifically to TL1a and inhibits interaction of TL1a and Death Receptor 3 (DR3) and which does not inhibit the interaction of TL1a and Decoy Receptor 3 (DcR3). The disclosure also provides uses of the TL1a-binding proteins.

Abstract: A mobile telecommunications network includes: a radio access network having radio means (2000) for wireless communication with a plurality of terminals (10) registered with the telecommunications network and control means (700) operable to provide services to the users of the terminals connected thereto, and a core (2030) including a store of policy information (9, 36) for respective ones of the terminals (10), and distribution means operable to provide to the control means associated with one of the terminals the policy information; wherein the control means is operable to store the policy information together with an indicator of the version of the policy information during periods when the terminal is disconnected from the control means, the control means including checking means for checking the currency of the policy using the indicator of the version of the policy and means for applying the stored policy information to the terminal when the terminal re-connects to the control means if the checking means

Abstract: A mobile telecommunications network includes: a radio access network having radio means (2000) for wireless communication with a plurality of terminals (10) registered with the telecommunications network and control means (700) operable to control interaction of the terminals with the radio access network; and a core (2030) including a store of policy information comprising group policy data (2210) applicable to a group of the terminals and individual policy data applicable to respective ones of the terminals (10), and distribution means operable to provide to the control means associated with each of the terminals an indicator of the group policy data applicable to each of the terminals and the individual policy data applicable to each of the terminals.

Abstract: A mobile telecommunications network includes: a radio access network having radio means (2000) for wireless communication with a plurality of terminals (10) registered with the telecommunications network and control means (700) operable to provide services to the users of the terminals connected thereto, and a core (2030) including a store of policy information (9, 36) for respective ones of the terminals (10), and distribution means operable to provide to the control means associated with one of the terminals the policy information; wherein the control means is operable to store the policy information together with an indicator of the version of the policy information during periods when the terminal is disconnected from the control means, the control means including checking means for checking the currency of the policy using the indicator of the version of the policy and means for applying the stored policy information to the terminal when the terminal re-connects to the control means if the checking means

Abstract: A mobile telecommunications network includes: a radio access network having radio means (2000) for wireless communication with a plurality of terminals (10) registered with the telecommunications network and control means (700) operable to provide services to the users of the terminals connected thereto; a core (2030) having content processing means (2200, 2250) operable to provide a core service relating to content; a cloud (2210) hosted content processing means (2220) operable to provide a cloud-based service relating to content corresponding to the core service; wherein the control means (700) is operable to transmit data to the cloud hosted content processing means (2220) for the performance of the cloud-based service thereon.