Abstract: Disclosed herein are systems and methods for neural interfaces. Neural interfaces may form minimally invasive and high-scalable bidirectional brain-computer interfaces, which may be used in the treatment of a variety of disorders of the brain and nervous system. Disclosed are methods for a minimally invasive technique for implanting neural interfaces, a neural interface configured to be placed between the brain and the dura and configured to record from and/or stimulate the cortical surface. Also disclosed are methods for attaching a plurality of microelectrode arrays to form a neural interface device, and fabricating neural interfaces including microelectrode arrays and pockets to facilitate their insertion. The disclosed systems and methods also include neural decoding techniques.

Abstract: A wire guide including a bracket for securing the wire guide to an external support, a housing, a holder for holding a nozzle extension, a main spring and an adjustment mechanism, and wherein the main spring is configured to allow the holder to float within the housing whilst a first end of the holder extends through an aperture formed in the housing and has a position adjustable with reference to the housing by the adjustment mechanism.