Patents by Inventor Adam R. Looker

Adam R. Looker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROCESS FOR MAKING MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR
    Publication number: 20100267768
    Abstract: The invention provides a process for the preparation of a compound of Formula 1, comprising coupling a carboxylic acid of Formula 2 with an aniline of Formula 3 in the presence of a coupling agent.
    Type: Application
    Filed: March 19, 2010
    Publication date: October 21, 2010
    Applicant: VERTEX PHARMACEUTICALS INCORPORATED
    Inventors: John DeMattei, Adam R. Looker, Bobbianna Neubert-Langille, Martin Trudeau, Stefanie Roeper, Michael P. Ryan, Dahrika Milfred Lao Yap, Brian R. Krueger, Peter D.J. Grootenhuis, Fredrick F. van Goor, Martyn C. Botfield, Gregor Zlokarnik
  • PROCESSES FOR PRODUCING PHENYL-6-(1-(PHENYL)UREIDO)NICOTINAMIDES)
    Publication number: 20100234606
    Abstract: The present invention relates to processes for the preparation of compounds useful as inhibitors of p38 kinase. The processes of the present invention are amenable for large scale preparation and produce stable phenyl-6-(1-(phenyl)ureido)nicotinamides in high purity and yields.
    Type: Application
    Filed: February 12, 2010
    Publication date: September 16, 2010
    Applicant: Vertex Pharmaceuticals Incorporated
    Inventors: Stefanie Roeper, Adam R. Looker, Theodore A. Martinot, Bobbianna Neubert-Langille, Michael P. Ryan, John R. Snoonian