Patents by Inventor Adam Rago

Adam Rago has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11944724
    Abstract: Systems and methods related to polymer foams are generally described. Some embodiments relate to compositions and methods for the preparation of polymer foams, and methods for using the polymer foams. The polymer foams can be applied to a body cavity and placed in contact with, for example, tissue, injured tissue, internal organs, etc. In some embodiments, the polymer foams can be formed within a body cavity (i.e., in situ foam formation). In addition, the foamed polymers may be capable of exerting a pressure on an internal surface of a body cavity and preventing or limiting movement of a bodily fluid (e.g., blood, etc.).
    Type: Grant
    Filed: December 13, 2021
    Date of Patent: April 2, 2024
    Assignee: ARSENAL MEDICAL, INC.
    Inventors: Upma Sharma, Irina Gitlin, Gregory T. Zugates, Adam Rago, Parisa Zamiri, Rany Busold, Robert J. Caulkins, Toby Freyman, Quynh Pham, Changcheng You, Jeffrey Carbeck
  • Publication number: 20230414840
    Abstract: Systems and methods related to polymer foams are generally described. Some embodiments relate to compositions and methods for the preparation of polymer foams, and methods for using the polymer foams. The polymer foams can be applied to a body cavity and placed in contact with, for example, tissue, injured tissue, internal organs, etc. In some embodiments, the polymer foams can be formed within a body cavity (i.e., in situ foam formation). In addition, the foamed polymers may be capable of exerting a pressure on an internal surface of a body cavity and preventing or limiting movement of a bodily fluid (e.g., blood, etc.).
    Type: Application
    Filed: September 12, 2023
    Publication date: December 28, 2023
    Inventors: Upma Sharma, Irina Gitlin, Gregory T. Zugates, Adam Rago, Parisa Zamiri, Rany Busold, Robert J. Caulkins, Toby Freyman, Quynh Pham, Changcheng You, Jeffrey Carbeck
  • Patent number: 11786642
    Abstract: Systems and methods related to polymer foams are generally described. Some embodiments relate to compositions and methods for the preparation of polymer foams, and methods for using the polymer foams. The polymer foams can be applied to a body cavity and placed in contact with, for example, tissue, injured tissue, internal organs, etc. In some embodiments, the polymer foams can be formed within a body cavity (i.e., in situ foam formation). In addition, the foamed polymers may be capable of exerting a pressure on an internal surface of a body cavity and preventing or limiting movement of a bodily fluid (e.g., blood, etc.).
    Type: Grant
    Filed: August 7, 2020
    Date of Patent: October 17, 2023
    Assignee: Arsenal Medical, Inc.
    Inventors: Upma Sharma, Irina Gitlin, Gregory T. Zugates, Adam Rago, Parisa Zamiri, Rany Busold, Toby Freyman, Robert J. Caulkins, Quynh P. Pham, Changcheng You, Jeffrey D. Carbeck
  • Publication number: 20220105248
    Abstract: Systems and methods related to polymer foams are generally described. Some embodiments relate to compositions and methods for the preparation of polymer foams, and methods for using the polymer foams. The polymer foams can be applied to a body cavity and placed in contact with, for example, tissue, injured tissue, internal organs, etc. In some embodiments, the polymer foams can be formed within a body cavity (i.e., in situ foam formation). In addition, the foamed polymers may be capable of exerting a pressure on an internal surface of a body cavity and preventing or limiting movement of a bodily fluid (e.g., blood, etc.).
    Type: Application
    Filed: December 13, 2021
    Publication date: April 7, 2022
    Inventors: Upma SHARMA, Irina GITLIN, Gregory T. ZUGATES, Adam RAGO, Parisa ZAMIRI, Rany BUSOLD, Robert J. CAULKINS, Toby FREYMAN, Quynh PHAM, Changcheng YOU, Jeffrey CARBECK
  • Patent number: 11246964
    Abstract: Systems and methods related to polymer foams are generally described. Some embodiments relate to compositions and methods for the preparation of polymer foams, and methods for using the polymer foams. The polymer foams can be applied to a body cavity and placed in contact with, for example, tissue, injured tissue, internal organs, etc. In some embodiments, the polymer foams can be formed within a body cavity (i.e., in situ foam formation). In addition, the foamed polymers may be capable of exerting a pressure on an internal surface of a body cavity and preventing or limiting movement of a bodily fluid (e.g., blood, etc.).
    Type: Grant
    Filed: April 5, 2019
    Date of Patent: February 15, 2022
    Assignee: Arsenal Medical, Inc.
    Inventors: Upma Sharma, Irina Gitlin, Gregory T. Zugates, Adam Rago, Parisa Zamiri, Rany Busold, Robert J. Caulkins, Toby Freyman, Quynh Pham, Changcheng You, Jeffrey Carbeck
  • Patent number: 10980920
    Abstract: Systems and methods related to polymer foams are generally described. Some embodiments relate to compositions and methods for the preparation of polymer foams, and methods for using the polymer foams. The polymer foams can be applied to a body cavity and placed in contact with, for example, tissue, injured tissue, internal organs, etc. In some embodiments, the polymer foams can be formed within a body cavity (i.e., in situ foam formation). In addition, the foamed polymers may be capable of exerting a pressure on an internal surface of a body cavity and preventing or limiting movement of a bodily fluid (e.g., blood, etc.).
    Type: Grant
    Filed: March 16, 2018
    Date of Patent: April 20, 2021
    Assignee: Arsenal Medical, Inc.
    Inventors: Upma Sharma, Irina Gitlin, Gregory T. Zugates, Adam Rago, Parisa Zamiri, Rany Busold, Robert J. Caulkins, Toby Freyman, Quynh Pham, Changcheng You, Jeffrey Carbeck
  • Publication number: 20210030467
    Abstract: One aspect of the invention provides a device for delivering material into a biological tissue. The device includes: a reservoir for the material; and a material delivery unit in connection with the reservoir configured to transfer the material from the reservoir to the tissue. Another aspect of the invention provides an implantable or insertable delivery device for delivery of material across or into a biological tissue in a subject. The device includes: a reservoir for holding the material; and a tissue-penetrating member.
    Type: Application
    Filed: February 8, 2019
    Publication date: February 4, 2021
    Applicant: Flagship Pioneering Innovations V, Inc.
    Inventors: Michael Mee, Adam Rago, Geoffrey von Maltzahn, John Miles Milwid, Jacob Rosenblum Rubens, Michael J. Cima
  • Publication number: 20210032589
    Abstract: One aspect of the invention provides an apparatus for isolating one or more subcellular components including a cell disruption reservoir that generates at least one of a phase change, a thermal change, a physical contact force, an ultrasonic frequency, an osmotic change, a pressure change, a photothermal pulse, a magnetic field, an electromagnetic field, an electric field, and an electrical pulse through the reservoir and a separation instrument configured to specifically isolate the subcellular components based on one or more parameters selected from at least one of density, charge/pH, dielectric polarization, magnetic attraction, spectral dispersion, spectral refraction, spectral diffraction, hydrophobicity, hydrophilicity, structure (presence or absence of a structural feature), function (migration), affinity or binding, and pressure.
    Type: Application
    Filed: February 8, 2019
    Publication date: February 4, 2021
    Applicant: Flagship Pioneering Innovations V, Inc.
    Inventors: Michael Mee, Adam Rago, Geoffrey von Maltzahn, John Miles Milwid, Jacob Rosenblum Rubens, Michael J. Cima
  • Publication number: 20200405921
    Abstract: Systems and methods related to polymer foams are generally described. Some embodiments relate to compositions and methods for the preparation of polymer foams, and methods for using the polymer foams. The polymer foams can be applied to a body cavity and placed in contact with, for example, tissue, injured tissue, internal organs, etc. In some embodiments, the polymer foams can be formed within a body cavity (i.e., in situ foam formation). In addition, the foamed polymers may be capable of exerting a pressure on an internal surface of a body cavity and preventing or limiting movement of a bodily fluid (e.g., blood, etc.).
    Type: Application
    Filed: August 7, 2020
    Publication date: December 31, 2020
    Inventors: Upma Sharma, Irina Gitlin, Gregory T. Zugates, Adam Rago, Parisa Zamiri, Rany Busold, Toby Freyman, Robert J. Caulkins, Quynh P. Pham, Changcheng You, Jeffrey D. Carbeck
  • Patent number: 10765781
    Abstract: Systems and methods related to polymer foams are generally described. Some embodiments relate to compositions and methods for the preparation of polymer foams, and methods for using the polymer foams. The polymer foams can be applied to a body cavity and placed in contact with, for example, tissue, injured tissue, internal organs, etc. In some embodiments, the polymer foams can be formed within a body cavity (i.e., in situ foam formation). In addition, the foamed polymers may be capable of exerting a pressure on an internal surface of a body cavity and preventing or limiting movement of a bodily fluid (e.g., blood, etc.).
    Type: Grant
    Filed: July 6, 2017
    Date of Patent: September 8, 2020
    Assignee: Arsenal Medical Inc.
    Inventors: Upma Sharma, Irina Gitlin, Gregory T. Zugates, Adam Rago, Parisa Zamiri, Rany Busold, Toby Freyman, Robert J. Caulkins, Quynh P Pham, Changcheng You, Jeffrey D. Carbeck
  • Patent number: 10687795
    Abstract: Delivery systems for in situ forming foam formulations are provided. The devices may include various actuation mechanisms and may entrain air into fluid formulation components in a variety of ways, including mixing with air and the addition of compressed gas.
    Type: Grant
    Filed: January 20, 2017
    Date of Patent: June 23, 2020
    Assignee: Arsenal Medical, Inc.
    Inventors: Upma Sharma, Rany Busold, Adam Rago, Gregory T. Zugates, Toby Freyman, Lisette Manrique Miller
  • Patent number: 10653422
    Abstract: Systems, methods and kits for treating hemorrhages within cavities are provided. The methods utilize the application of a rapid spike of pressure to the closed cavity, followed by a steady state pressure or pressures.
    Type: Grant
    Filed: October 11, 2017
    Date of Patent: May 19, 2020
    Assignee: Arsenal Medical, Inc.
    Inventors: Adam Rago, John Marini, Gregory T. Zugates, Marc Helmick, Upma Sharma
  • Publication number: 20190240380
    Abstract: Systems and methods related to polymer foams are generally described. Some embodiments relate to compositions and methods for the preparation of polymer foams, and methods for using the polymer foams. The polymer foams can be applied to a body cavity and placed in contact with, for example, tissue, injured tissue, internal organs, etc. In some embodiments, the polymer foams can be formed within a body cavity (i.e., in situ foam formation). In addition, the foamed polymers may be capable of exerting a pressure on an internal surface of a body cavity and preventing or limiting movement of a bodily fluid (e.g., blood, etc.).
    Type: Application
    Filed: April 5, 2019
    Publication date: August 8, 2019
    Inventors: Upma SHARMA, Irina GITLIN, Gregory T. ZUGATES, Adam RAGO, Parisa ZAMIRI, Rany BUSOLD, Robert J. CAULKINS, Toby FREYMAN, Quynh PHAM, Changcheng YOU, Jeffrey CARBECK
  • Patent number: 10307515
    Abstract: Systems and methods related to polymer foams are generally described. Some embodiments relate to compositions and methods for the preparation of polymer foams, and methods for using the polymer foams. The polymer foams can be applied to a body cavity and placed in contact with, for example, tissue, injured tissue, internal organs, etc. In some embodiments, the polymer foams can be formed within a body cavity (i.e., in situ foam formation). In addition, the foamed polymers may be capable of exerting a pressure on an internal surface of a body cavity and preventing or limiting movement of a bodily fluid (e.g., blood, etc.).
    Type: Grant
    Filed: October 30, 2015
    Date of Patent: June 4, 2019
    Assignee: Arsenal Medical Inc.
    Inventors: Upma Sharma, Irina Gitlin, Gregory T. Zugates, Adam Rago, Parisa Zamiri, Rany Busold, Robert J. Caulkins, Toby Freyman, Quynh Pham, Changcheng You, Jeffrey Carbeck
  • Patent number: 10293076
    Abstract: Systems, methods and kits for treating hemorrhages within cavities are provided. The methods utilize the application of a rapid spike of pressure to the closed cavity, followed by a steady state pressure or pressures.
    Type: Grant
    Filed: November 18, 2016
    Date of Patent: May 21, 2019
    Assignee: Arsenal Medical, Inc.
    Inventors: Adam Rago, John Marini, Gregory T. Zugates, Marc Helmick, Upma Sharma
  • Publication number: 20180256774
    Abstract: Systems, methods and kits for treating hemorrhages within cavities are provided. The methods utilize the application of a rapid spike of pressure to the closed cavity, followed by a steady state pressure or pressures.
    Type: Application
    Filed: November 18, 2016
    Publication date: September 13, 2018
    Inventors: Adam Rago, John Marini, Gregory T. Zugates, Marc Helmick, Upma Sharma
  • Publication number: 20180250446
    Abstract: Systems and methods related to polymer foams are generally described. Some embodiments relate to compositions and methods for the preparation of polymer foams, and methods for using the polymer foams. The polymer foams can be applied to a body cavity and placed in contact with, for example, tissue, injured tissue, internal organs, etc. In some embodiments, the polymer foams can be formed within a body cavity (i.e., in situ foam formation). In addition, the foamed polymers may be capable of exerting a pressure on an internal surface of a body cavity and preventing or limiting movement of a bodily fluid (e.g., blood, etc.).
    Type: Application
    Filed: March 16, 2018
    Publication date: September 6, 2018
    Inventors: Upma SHARMA, Irina GITLIN, Gregory T. ZUGATES, Adam RAGO, Parisa ZAMIRI, Rany BUSOLD, Robert J. CAULKINS, Toby FREYMAN, Quynh PHAM, Changcheng YOU, Jeffrey CARBECK
  • Patent number: 10052107
    Abstract: Systems and method for treating aneurysms are provided which utilize formulations that form polymer foams in situ. The formulations generally have a buoyancy greater than or less than blood, and either float to the top of the aneurysm and foam from the top down or sink to the bottom and foam from the bottom up.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: August 21, 2018
    Assignee: ARSENAL MEDICAL, INC.
    Inventors: Rany Busold, John Marini, Upma Sharma, Adam Rago, Jennifer Mortensen, Joseph Lomakin, Gregory T. Zugates, Janet Komatsu, Jeffrey Groom, III
  • Publication number: 20180177507
    Abstract: Systems and method for treating aneurysms are provided which utilize formulations that form polymer foams in situ. The formulations generally have a buoyancy greater than or less than blood, and either float to the top of the aneurysm and foam from the top down or sink to the bottom and foam from the bottom up.
    Type: Application
    Filed: March 14, 2014
    Publication date: June 28, 2018
    Inventors: Rany Busold, John Marini, Upma Sharma, Adam Rago, Jennifer Mortensen, Joseph Lomakin, Gregory T. Zugates, Janet Komatsu, Jeffrey Groom, III
  • Publication number: 20180140740
    Abstract: Systems, methods and kits for treating hemorrhages within cavities are provided. The methods utilize the application of a rapid spike of pressure to the closed cavity, followed by a steady state pressure or pressures.
    Type: Application
    Filed: November 18, 2016
    Publication date: May 24, 2018
    Inventors: Adam Rago, John Marini, Gregory T. Zugates, Marc Helmick, Upma Sharma