Patents by Inventor Adam Rago
Adam Rago has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11944724Abstract: Systems and methods related to polymer foams are generally described. Some embodiments relate to compositions and methods for the preparation of polymer foams, and methods for using the polymer foams. The polymer foams can be applied to a body cavity and placed in contact with, for example, tissue, injured tissue, internal organs, etc. In some embodiments, the polymer foams can be formed within a body cavity (i.e., in situ foam formation). In addition, the foamed polymers may be capable of exerting a pressure on an internal surface of a body cavity and preventing or limiting movement of a bodily fluid (e.g., blood, etc.).Type: GrantFiled: December 13, 2021Date of Patent: April 2, 2024Assignee: ARSENAL MEDICAL, INC.Inventors: Upma Sharma, Irina Gitlin, Gregory T. Zugates, Adam Rago, Parisa Zamiri, Rany Busold, Robert J. Caulkins, Toby Freyman, Quynh Pham, Changcheng You, Jeffrey Carbeck
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Publication number: 20230414840Abstract: Systems and methods related to polymer foams are generally described. Some embodiments relate to compositions and methods for the preparation of polymer foams, and methods for using the polymer foams. The polymer foams can be applied to a body cavity and placed in contact with, for example, tissue, injured tissue, internal organs, etc. In some embodiments, the polymer foams can be formed within a body cavity (i.e., in situ foam formation). In addition, the foamed polymers may be capable of exerting a pressure on an internal surface of a body cavity and preventing or limiting movement of a bodily fluid (e.g., blood, etc.).Type: ApplicationFiled: September 12, 2023Publication date: December 28, 2023Inventors: Upma Sharma, Irina Gitlin, Gregory T. Zugates, Adam Rago, Parisa Zamiri, Rany Busold, Robert J. Caulkins, Toby Freyman, Quynh Pham, Changcheng You, Jeffrey Carbeck
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Patent number: 11786642Abstract: Systems and methods related to polymer foams are generally described. Some embodiments relate to compositions and methods for the preparation of polymer foams, and methods for using the polymer foams. The polymer foams can be applied to a body cavity and placed in contact with, for example, tissue, injured tissue, internal organs, etc. In some embodiments, the polymer foams can be formed within a body cavity (i.e., in situ foam formation). In addition, the foamed polymers may be capable of exerting a pressure on an internal surface of a body cavity and preventing or limiting movement of a bodily fluid (e.g., blood, etc.).Type: GrantFiled: August 7, 2020Date of Patent: October 17, 2023Assignee: Arsenal Medical, Inc.Inventors: Upma Sharma, Irina Gitlin, Gregory T. Zugates, Adam Rago, Parisa Zamiri, Rany Busold, Toby Freyman, Robert J. Caulkins, Quynh P. Pham, Changcheng You, Jeffrey D. Carbeck
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Publication number: 20220105248Abstract: Systems and methods related to polymer foams are generally described. Some embodiments relate to compositions and methods for the preparation of polymer foams, and methods for using the polymer foams. The polymer foams can be applied to a body cavity and placed in contact with, for example, tissue, injured tissue, internal organs, etc. In some embodiments, the polymer foams can be formed within a body cavity (i.e., in situ foam formation). In addition, the foamed polymers may be capable of exerting a pressure on an internal surface of a body cavity and preventing or limiting movement of a bodily fluid (e.g., blood, etc.).Type: ApplicationFiled: December 13, 2021Publication date: April 7, 2022Inventors: Upma SHARMA, Irina GITLIN, Gregory T. ZUGATES, Adam RAGO, Parisa ZAMIRI, Rany BUSOLD, Robert J. CAULKINS, Toby FREYMAN, Quynh PHAM, Changcheng YOU, Jeffrey CARBECK
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Patent number: 11246964Abstract: Systems and methods related to polymer foams are generally described. Some embodiments relate to compositions and methods for the preparation of polymer foams, and methods for using the polymer foams. The polymer foams can be applied to a body cavity and placed in contact with, for example, tissue, injured tissue, internal organs, etc. In some embodiments, the polymer foams can be formed within a body cavity (i.e., in situ foam formation). In addition, the foamed polymers may be capable of exerting a pressure on an internal surface of a body cavity and preventing or limiting movement of a bodily fluid (e.g., blood, etc.).Type: GrantFiled: April 5, 2019Date of Patent: February 15, 2022Assignee: Arsenal Medical, Inc.Inventors: Upma Sharma, Irina Gitlin, Gregory T. Zugates, Adam Rago, Parisa Zamiri, Rany Busold, Robert J. Caulkins, Toby Freyman, Quynh Pham, Changcheng You, Jeffrey Carbeck
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Patent number: 10980920Abstract: Systems and methods related to polymer foams are generally described. Some embodiments relate to compositions and methods for the preparation of polymer foams, and methods for using the polymer foams. The polymer foams can be applied to a body cavity and placed in contact with, for example, tissue, injured tissue, internal organs, etc. In some embodiments, the polymer foams can be formed within a body cavity (i.e., in situ foam formation). In addition, the foamed polymers may be capable of exerting a pressure on an internal surface of a body cavity and preventing or limiting movement of a bodily fluid (e.g., blood, etc.).Type: GrantFiled: March 16, 2018Date of Patent: April 20, 2021Assignee: Arsenal Medical, Inc.Inventors: Upma Sharma, Irina Gitlin, Gregory T. Zugates, Adam Rago, Parisa Zamiri, Rany Busold, Robert J. Caulkins, Toby Freyman, Quynh Pham, Changcheng You, Jeffrey Carbeck
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Publication number: 20210032589Abstract: One aspect of the invention provides an apparatus for isolating one or more subcellular components including a cell disruption reservoir that generates at least one of a phase change, a thermal change, a physical contact force, an ultrasonic frequency, an osmotic change, a pressure change, a photothermal pulse, a magnetic field, an electromagnetic field, an electric field, and an electrical pulse through the reservoir and a separation instrument configured to specifically isolate the subcellular components based on one or more parameters selected from at least one of density, charge/pH, dielectric polarization, magnetic attraction, spectral dispersion, spectral refraction, spectral diffraction, hydrophobicity, hydrophilicity, structure (presence or absence of a structural feature), function (migration), affinity or binding, and pressure.Type: ApplicationFiled: February 8, 2019Publication date: February 4, 2021Applicant: Flagship Pioneering Innovations V, Inc.Inventors: Michael Mee, Adam Rago, Geoffrey von Maltzahn, John Miles Milwid, Jacob Rosenblum Rubens, Michael J. Cima
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Publication number: 20210030467Abstract: One aspect of the invention provides a device for delivering material into a biological tissue. The device includes: a reservoir for the material; and a material delivery unit in connection with the reservoir configured to transfer the material from the reservoir to the tissue. Another aspect of the invention provides an implantable or insertable delivery device for delivery of material across or into a biological tissue in a subject. The device includes: a reservoir for holding the material; and a tissue-penetrating member.Type: ApplicationFiled: February 8, 2019Publication date: February 4, 2021Applicant: Flagship Pioneering Innovations V, Inc.Inventors: Michael Mee, Adam Rago, Geoffrey von Maltzahn, John Miles Milwid, Jacob Rosenblum Rubens, Michael J. Cima
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Publication number: 20200405921Abstract: Systems and methods related to polymer foams are generally described. Some embodiments relate to compositions and methods for the preparation of polymer foams, and methods for using the polymer foams. The polymer foams can be applied to a body cavity and placed in contact with, for example, tissue, injured tissue, internal organs, etc. In some embodiments, the polymer foams can be formed within a body cavity (i.e., in situ foam formation). In addition, the foamed polymers may be capable of exerting a pressure on an internal surface of a body cavity and preventing or limiting movement of a bodily fluid (e.g., blood, etc.).Type: ApplicationFiled: August 7, 2020Publication date: December 31, 2020Inventors: Upma Sharma, Irina Gitlin, Gregory T. Zugates, Adam Rago, Parisa Zamiri, Rany Busold, Toby Freyman, Robert J. Caulkins, Quynh P. Pham, Changcheng You, Jeffrey D. Carbeck
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Patent number: 10765781Abstract: Systems and methods related to polymer foams are generally described. Some embodiments relate to compositions and methods for the preparation of polymer foams, and methods for using the polymer foams. The polymer foams can be applied to a body cavity and placed in contact with, for example, tissue, injured tissue, internal organs, etc. In some embodiments, the polymer foams can be formed within a body cavity (i.e., in situ foam formation). In addition, the foamed polymers may be capable of exerting a pressure on an internal surface of a body cavity and preventing or limiting movement of a bodily fluid (e.g., blood, etc.).Type: GrantFiled: July 6, 2017Date of Patent: September 8, 2020Assignee: Arsenal Medical Inc.Inventors: Upma Sharma, Irina Gitlin, Gregory T. Zugates, Adam Rago, Parisa Zamiri, Rany Busold, Toby Freyman, Robert J. Caulkins, Quynh P Pham, Changcheng You, Jeffrey D. Carbeck
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Patent number: 10687795Abstract: Delivery systems for in situ forming foam formulations are provided. The devices may include various actuation mechanisms and may entrain air into fluid formulation components in a variety of ways, including mixing with air and the addition of compressed gas.Type: GrantFiled: January 20, 2017Date of Patent: June 23, 2020Assignee: Arsenal Medical, Inc.Inventors: Upma Sharma, Rany Busold, Adam Rago, Gregory T. Zugates, Toby Freyman, Lisette Manrique Miller
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Patent number: 10653422Abstract: Systems, methods and kits for treating hemorrhages within cavities are provided. The methods utilize the application of a rapid spike of pressure to the closed cavity, followed by a steady state pressure or pressures.Type: GrantFiled: October 11, 2017Date of Patent: May 19, 2020Assignee: Arsenal Medical, Inc.Inventors: Adam Rago, John Marini, Gregory T. Zugates, Marc Helmick, Upma Sharma
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Publication number: 20190240380Abstract: Systems and methods related to polymer foams are generally described. Some embodiments relate to compositions and methods for the preparation of polymer foams, and methods for using the polymer foams. The polymer foams can be applied to a body cavity and placed in contact with, for example, tissue, injured tissue, internal organs, etc. In some embodiments, the polymer foams can be formed within a body cavity (i.e., in situ foam formation). In addition, the foamed polymers may be capable of exerting a pressure on an internal surface of a body cavity and preventing or limiting movement of a bodily fluid (e.g., blood, etc.).Type: ApplicationFiled: April 5, 2019Publication date: August 8, 2019Inventors: Upma SHARMA, Irina GITLIN, Gregory T. ZUGATES, Adam RAGO, Parisa ZAMIRI, Rany BUSOLD, Robert J. CAULKINS, Toby FREYMAN, Quynh PHAM, Changcheng YOU, Jeffrey CARBECK
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Patent number: 10307515Abstract: Systems and methods related to polymer foams are generally described. Some embodiments relate to compositions and methods for the preparation of polymer foams, and methods for using the polymer foams. The polymer foams can be applied to a body cavity and placed in contact with, for example, tissue, injured tissue, internal organs, etc. In some embodiments, the polymer foams can be formed within a body cavity (i.e., in situ foam formation). In addition, the foamed polymers may be capable of exerting a pressure on an internal surface of a body cavity and preventing or limiting movement of a bodily fluid (e.g., blood, etc.).Type: GrantFiled: October 30, 2015Date of Patent: June 4, 2019Assignee: Arsenal Medical Inc.Inventors: Upma Sharma, Irina Gitlin, Gregory T. Zugates, Adam Rago, Parisa Zamiri, Rany Busold, Robert J. Caulkins, Toby Freyman, Quynh Pham, Changcheng You, Jeffrey Carbeck
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Patent number: 10293076Abstract: Systems, methods and kits for treating hemorrhages within cavities are provided. The methods utilize the application of a rapid spike of pressure to the closed cavity, followed by a steady state pressure or pressures.Type: GrantFiled: November 18, 2016Date of Patent: May 21, 2019Assignee: Arsenal Medical, Inc.Inventors: Adam Rago, John Marini, Gregory T. Zugates, Marc Helmick, Upma Sharma
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Publication number: 20180256774Abstract: Systems, methods and kits for treating hemorrhages within cavities are provided. The methods utilize the application of a rapid spike of pressure to the closed cavity, followed by a steady state pressure or pressures.Type: ApplicationFiled: November 18, 2016Publication date: September 13, 2018Inventors: Adam Rago, John Marini, Gregory T. Zugates, Marc Helmick, Upma Sharma
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Publication number: 20180250446Abstract: Systems and methods related to polymer foams are generally described. Some embodiments relate to compositions and methods for the preparation of polymer foams, and methods for using the polymer foams. The polymer foams can be applied to a body cavity and placed in contact with, for example, tissue, injured tissue, internal organs, etc. In some embodiments, the polymer foams can be formed within a body cavity (i.e., in situ foam formation). In addition, the foamed polymers may be capable of exerting a pressure on an internal surface of a body cavity and preventing or limiting movement of a bodily fluid (e.g., blood, etc.).Type: ApplicationFiled: March 16, 2018Publication date: September 6, 2018Inventors: Upma SHARMA, Irina GITLIN, Gregory T. ZUGATES, Adam RAGO, Parisa ZAMIRI, Rany BUSOLD, Robert J. CAULKINS, Toby FREYMAN, Quynh PHAM, Changcheng YOU, Jeffrey CARBECK
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Patent number: 10052107Abstract: Systems and method for treating aneurysms are provided which utilize formulations that form polymer foams in situ. The formulations generally have a buoyancy greater than or less than blood, and either float to the top of the aneurysm and foam from the top down or sink to the bottom and foam from the bottom up.Type: GrantFiled: March 14, 2014Date of Patent: August 21, 2018Assignee: ARSENAL MEDICAL, INC.Inventors: Rany Busold, John Marini, Upma Sharma, Adam Rago, Jennifer Mortensen, Joseph Lomakin, Gregory T. Zugates, Janet Komatsu, Jeffrey Groom, III
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Publication number: 20180177507Abstract: Systems and method for treating aneurysms are provided which utilize formulations that form polymer foams in situ. The formulations generally have a buoyancy greater than or less than blood, and either float to the top of the aneurysm and foam from the top down or sink to the bottom and foam from the bottom up.Type: ApplicationFiled: March 14, 2014Publication date: June 28, 2018Inventors: Rany Busold, John Marini, Upma Sharma, Adam Rago, Jennifer Mortensen, Joseph Lomakin, Gregory T. Zugates, Janet Komatsu, Jeffrey Groom, III
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Publication number: 20180140740Abstract: Systems, methods and kits for treating hemorrhages within cavities are provided. The methods utilize the application of a rapid spike of pressure to the closed cavity, followed by a steady state pressure or pressures.Type: ApplicationFiled: November 18, 2016Publication date: May 24, 2018Inventors: Adam Rago, John Marini, Gregory T. Zugates, Marc Helmick, Upma Sharma