Abstract: Devices, systems and methods for monitoring patient adherence to treatment regimens are described herein. In some embodiments, a medication dispensing system includes a medication dispensing device and a monitor. The medication dispensing device is configured to receive dose containers, and includes a dispensing mechanism that is operable to dispense at least one of the dose containers at a predetermined time based on a prescribed treatment regimen. Each of the dose containers defines an interior region configured to contain a plurality of individual medications. The medication dispensing device also includes an event detection system including a plurality of sensors configured to detect a change in status of the medication dispensing device and/or a change in the dose containers, and a control unit configured to operate the dispensing mechanism and the event detection system, and to communicate with a monitor (e.g., a remote server or any third-party monitor) and a user.

Abstract: A medication loading system includes a mask including a first portion and a second portion. The first portion includes a plurality of receptacles configured to receive medication. The second portion includes a plurality of openings and is movable relative to the first portion between a first and a second configuration. In the first configuration, the plurality of receptacles are obstructed by the second portion. In the second configuration, the plurality of receptacles are in communication with a medication storage device through the plurality of openings to allow the medication to fall through the opening into a dose container of the medication storage device. The medication loading system also includes an imaging system configured to capture an image of the mask and operative to determine if (a) the medication is loaded in the correct receptacle, and (b) the correct medication is loaded in one or more of the plurality of receptacles.