Abstract: A control device for controlling an electrical load may include a slider knob, a plurality of light sources, a diffuser, and a control circuit. The slider knob may be configured to move in a vertical direction along an elongated slot located in a bezel of the control device. The diffuser may be located along the elongated slot and be configured to be illuminated by the plurality of light sources to indicate the amount of power delivered to the electrical load. The control circuit may be configured to control the amount of power delivered to the electrical load in response movement of the slider knob along the elongated slot, and to illuminate at least a portion of the diffuser to indicate the amount of power delivered to the electrical load.

Abstract: Among the various aspects of the present disclosure is the provision of a compositions for binding sphingosine-1-phosphate receptor 1 (S1P1), imaging of S1P1, and methods of use thereof. Provided are imaging agents for imaging S1P1 and S1P1 associated diseases, disorders, and conditions. Also provided are therapeutic compositions and methods for the treatment of S1P1 associated diseases, disorders, and conditions.

Abstract: Among the various aspects of the present disclosure is the provision of a compositions for binding sphingosine-1-phosphate receptor 1 (S1P1), imaging of S1P1, and methods of use thereof. Provided are imaging agents for imaging S1P1 and S1P1 associated diseases, disorders, and conditions. Also provided are therapeutic compositions and methods for the treatment of S1P1 associated diseases, disorders, and conditions.

Abstract: Members of a traveler's social network or “friends” are identified by a social recommendation service. The identified friends may possess knowledge regarding travel information of interest to the traveler. The identification may be based on locations of the friends and/or information of interest, selection criteria provided by the traveler, clickstream data for the friends, the relationship between the friends and the traveler, etc. The social recommendation service may additionally provide the traveler with identifying information enabling the user to communicate with the identified friend(s).

Abstract: A method for transforming transactional data into a forecast and confidence interval for controlling a commerce system involves moving goods between members of a commerce system, and recording transaction data related to movement of goods between the members of the commerce system. The transaction data includes price, product, time, and promotion. The model parameters are estimated based on the transactional data using a demand model to generate a forecast of demand for the goods based on a proposed price or promotion. A confidence interval of the certainty associated with the forecast of demand for the goods is determined based on the proposed price or promotion. The forecast of demand for the goods and confidence interval is provided to the commerce system to control the movement of goods based on the forecast of demand for the goods and confidence interval. The forecast and confidence interval can be graphically displayed.

Abstract: A method for transforming transactional data into a forecast and confidence interval for controlling a commerce system involves moving goods between members of a commerce system, and recording transaction data related to movement of goods between the members of the commerce system. The transaction data includes price, product, time, and promotion. The model parameters are estimated based on the transactional data using a demand model to generate a forecast of demand for the goods based on a proposed price or promotion. A confidence interval of the certainty associated with the forecast of demand for the goods is determined based on the proposed price or promotion. The forecast of demand for the goods and confidence interval is provided to the commerce system to control the movement of goods based on the forecast of demand for the goods and confidence interval. The forecast and confidence interval can be graphically displayed.

Abstract: Methods and compositions useful in the treatment or prevention of synucleinopathies, such as Parkinson's Disease, Diffuse Lewy Body Disease, and Multiple System Atrophy, or other neurodegenerative diseases are provided. The treatment including administering to a subject a farnesyl transferase inhibitor compound.