Abstract: In one aspect, the disclosed system for measuring a pose of a trailer connected to an autonomous truck includes a trailer pose sensor and an autonomy computing system. The sensor is coupled to a connector configured to rigidly mate with a trailer connector on the trailer. The sensor is configured to detect a motion of the trailer. The autonomy computing system is communicatively coupled to the sensor. The autonomy computing system includes a processor coupled to a memory, the memory storing executable instructions that, upon execution by the processor, configure the processor to: compute a first pose of the trailer and store in the memory, receive a first measurement of the motion from the sensor, compute a second pose based at least in part on the first measurement received from the sensor and the first pose, and store the second pose in the memory.

Abstract: The invention relates generally to polypeptides comprising a lectin domain, multimeric proteins comprising the polypeptides, and use of the polypeptides or multimeric proteins in the detection of a carbohydrate (e.g., a sialic acid containing carbohydrate or Siglec ligand) or the treatment of a Siglec-mediated disorder.