Patents by Inventor Adam Siegel
Adam Siegel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220061595Abstract: A portable sanitizer dispenser including a body that securely encloses a bottle of sanitizer, an attachment mechanism operatively attached to the body, and a dispensing mechanism operatively attached at a mouth of the bottle or at a bottom of the body. A method of using the portable sanitizer dispenser, by attaching the portable sanitizer dispenser to an object with an attachment mechanism operatively attached to a body, actuating a dispensing mechanism operatively attached to the body, and dispensing sanitizer.Type: ApplicationFiled: August 31, 2021Publication date: March 3, 2022Inventors: Aaron SIEGEL, Adam SIEGEL, Aviel SIEGEL
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Publication number: 20210284442Abstract: A trash receptacle including a hollow receptacle body having an open top end and a closed bottom end, the hollow receptacle body having a bag dispenser receptacle operatively connected to a bag dispenser port on an outer portion, and an air freshener receiver operatively connected to the hollow receptacle body and including an airflow mechanism for flowing air between the air freshener receiver and the hollow receptacle body. A method of using the trash receptacle by removing a bag from the bag dispenser receptacle on the outer portion of the hollow receptacle body, inserting the bag into the hollow receptacle body, and flowing air through the airflow mechanism and the air freshener receiver to maintain a clean smelling trash receptacle.Type: ApplicationFiled: August 26, 2020Publication date: September 16, 2021Inventors: Aaron SIEGEL, Adam SIEGEL, Aviel SIEGEL
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Patent number: 10082507Abstract: An assay method is described, which comprises the steps of immobilizing a binding partner (e.g., an antigen or antibody) for an analyte to be detected (e.g., an antibody or antigen) on a portion of a surface of a microfluidic chamber; passing a fluid sample over the surface and allowing the analyte to bind to the binding partner; allowing a metal colloid, e.g., a gold-conjugated antibody, to associate with the bound analyte; flowing a metal solution, e.g., a silver solution, over the surface such as to form an opaque metallic layer; and detecting the presence of said metallic layer, e.g., by visual inspection or by measuring light transmission through the layer, conductivity or resistance of the layer, or metal concentration in the metal solution after flowing the metal solution over the surface.Type: GrantFiled: September 30, 2013Date of Patent: September 25, 2018Assignee: President and Fellows of Harvard CollegeInventors: Samuel K. Sia, Vincent Linder, Babak Parviz, Adam Siegel, George M. Whitesides
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Patent number: 8985547Abstract: A microfluidic valve assembly includes a structure defining a microfluidic fluid path and an actuator that can be moved between different positions controlling flow through the channel. In one embodiment, the actuator can be threaded into at least a portion of the structure, and can be moved rotationally between a first position, causing relatively greater constriction of a microfluidic fluid path, and a second position causing relatively lesser constriction of the fluid path. Actuating the actuator, e.g., by rotation, can deform material between the valve and the fluid path, thereby constricting at least a portion of the underlying fluid path and regulating the flow of a fluid in the fluid path. In another aspect, the invention provides a reservoir into which fluid can be placed and from which fluid can be introduced into a microfluidic system. In one embodiment, the reservoir is expandable and thereby able to store fluid under pressure for delivery to a microfluidic system.Type: GrantFiled: January 31, 2006Date of Patent: March 24, 2015Assignee: President and Fellows of Harvard CollegeInventors: Douglas B. Weibel, Andrew Lee, Scott Potenta, Adam Siegel, Maarten Kruithof, George M. Whitesides
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Publication number: 20140134603Abstract: An assay method is described, which comprises the steps of immobilizing a binding partner (e.g., an antigen or antibody) for an analyte to be detected (e.g., an antibody or antigen) on a portion of a surface of a microfluidic chamber; passing a fluid sample over the surface and allowing the analyte to bind to the binding partner; allowing a metal colloid, e.g., a gold-conjugated antibody, to associate with the bound analyte; flowing a metal solution, e.g., a silver solution, over the surface such as to form an opaque metallic layer; and detecting the presence of said metallic layer, e.g., by visual inspection or by measuring light transmission through the layer, conductivity or resistance of the layer, or metal concentration in the metal solution after flowing the metal solution over the surface.Type: ApplicationFiled: September 30, 2013Publication date: May 15, 2014Inventors: Samuel K. Sia, Vincent Linder, Babak Amir-parviz, Adam Siegel, George M. Whitesides
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Patent number: 8574924Abstract: An assay method is described, which comprises the steps of immobilizing a binding partner (e.g., an antigen or antibody) for an analyte to be detected (e.g., an antibody or antigen) on a portion of a surface of a microfluidic chamber; passing a fluid sample over the surface and allowing the analyte to bind to the binding partner; allowing a metal colloid, e.g., a gold-conjugated antibody, to associate with the bound analyte; flowing a metal solution, e.g., a silver solution, over the surface such as to form an opaque metallic layer; and detecting the presence of said metallic layer, e.g., by visual inspection or by measuring light transmission through the layer, conductivity or resistance of the layer, or metal concentration in the metal solution after flowing the metal solution over the surface.Type: GrantFiled: April 28, 2010Date of Patent: November 5, 2013Assignee: President and Fellows of Harvard CollegeInventors: Samuel K. Sia, Vincent Linder, Babak Amir-Parviz, Adam Siegel, George M. Whitesides
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Patent number: 8501416Abstract: The present invention relates generally to microfluidic structures, and more specifically, to microfluidic structures and methods including meandering and wide channels. Microfluidic systems can provide an advantageous environment for performing various reactions and analysis due to a reduction in sample and reagent quantities that are required, a reduction in the size of the operating system, and a decrease in reaction time compared to conventional systems. Unfortunately, the small size of microfluidic channels can sometimes result in difficulty in detecting a species without magnifying optics (such as a microscope or a photomultiplier). A series of tightly packed microchannels, i.e., a meandering region, or a wide channel having a dimension on the order of millimeters, can serve as a solution to this problem by creating a wide measurement area.Type: GrantFiled: April 19, 2006Date of Patent: August 6, 2013Assignee: President and Fellows of Harvard CollegeInventors: Vincent Linder, Samuel K. Sia, George M. Whitesides, Max Narovlyansky, Adam Siegel
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Patent number: 8486833Abstract: Disclosed herein are a variety of microfluidic devices and solid, typically electrically conductive devices that can be formed using such devices as molds. In certain embodiments, the devices that are formed comprise conductive pathways formed by solidifying a liquid metal present in one or more microfluidic channels (such devices hereinafter referred to as “microsolidic” devices). In certain such devices, in which electrical connections can be formed and/or reformed between regions in a microfluidic structure; in some cases, the devices/circuits formed may be flexible and/or involve flexible electrical components. In certain embodiments, the solid metal wires/conductive pathways formed in microfluidic channel(s) may remain contained within the microfluidic structure. In certain such embodiments, the conductive pathways formed may be located in proximity to other microfluidic channel(s) of the structure that carry flowing fluid, such that the conductive pathway can create energy (e.g.Type: GrantFiled: May 18, 2006Date of Patent: July 16, 2013Assignee: President and Fellows of Harvard CollegeInventors: Derek A. Bruzewicz, Mila Boncheva-Bettex, George M. Whitesides, Adam Siegel, Douglas B. Weibel, Sergey S. Shevkoplyas, Andres Martinez
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Publication number: 20110045577Abstract: Disclosed herein are a variety of microfluidic devices and solid, typically electrically conductive devices that can be formed using such devices as molds. In certain embodiments, the devices that are formed comprise conductive pathways formed by solidifying a liquid metal present in one or more microfluidic channels (such devices hereinafter referred to as “microsolidic” devices). In certain such devices, in which electrical connections can be formed and/or reformed between regions in a microfluidic structure; in some cases, the devices/circuits formed may be flexible and/or involve flexible electrical components. In certain embodiments, the solid metal wires/conductive pathways formed in microfluidic channel(s) may remain contained within the microfluidic structure. In certain such embodiments, the conductive pathways formed may be located in proximity to other microfluidic channel(s) of the structure that carry flowing fluid, such that the conductive pathway can create energy (e.g.Type: ApplicationFiled: May 18, 2006Publication date: February 24, 2011Applicant: PRESIDENT AND FELLOWS OF HARVARD COLLEGEInventors: Derek A. Bruzewicz, Mila Boncheva-Bettex, George M. Whitesides, Adam Siegel, Douglas B. Weibel, Sergey S. Shevkoplyas, Andres Martinez
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Publication number: 20100279310Abstract: An assay method is described, which comprises the steps of immobilizing a binding partner (e.g., an antigen or antibody) for an analyte to be detected (e.g., an antibody or antigen) on a portion of a surface of a microfluidic chamber; passing a fluid sample over the surface and allowing the analyte to bind to the binding partner; allowing a metal colloid, e.g., a gold-conjugated antibody, to associate with the bound analyte; flowing a metal solution, e.g., a silver solution, over the surface such as to form an opaque metallic layer; and detecting the presence of said metallic layer, e.g., by visual inspection or by measuring light transmission through the layer, conductivity or resistance of the layer, or metal concentration in the metal solution after flowing the metal solution over the surface.Type: ApplicationFiled: April 28, 2010Publication date: November 4, 2010Applicant: President and Fellows of Harvard CollegeInventors: Samuel K. Sia, Vincent Linder, Adam Siegel, George M. Whitesides, Babak Amir-Parviz
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Patent number: 7736890Abstract: An assay method is described, which comprises the steps of immobilizing a binding partner (e.g., an antigen or antibody) for an analyte to be detected (e.g., an antibody or antigen) on a portion (140) of a surface (130) of a microfluidic chamber (120,122,124); passing a fluid sample over the surface and allowing the analyte to bind to the binding partner; allowing a metal colloid, e.g., a gold-conjugated antibody, to associate with the bound analyte; flowing a metal solution, e.g., a silver solution, over the surface such as to form an opaque metallic layer; and detecting the presence of said metallic layer, e.g., by visual inspection or by measuring light transmission through the layer, conductivity or resistance of the layer, or metal concentration in the metal solution after flowing the metal solution over the surface.Type: GrantFiled: December 29, 2004Date of Patent: June 15, 2010Assignee: President and Fellows of Harvard CollegeInventors: Samuel K. Sia, Vincent Linder, Babak Amir-Parviz, Adam Siegel, George M. Whitesides
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Publication number: 20100116343Abstract: A microfluidic valve assembly includes a structure defining a microfluidic fluid path and an actuator that can be moved between different positions controlling flow through the channel. In one embodiment, the actuator can be threaded into at least a portion of the structure, and can be moved rotationally between a first position, causing relatively greater constriction of a microfluidic fluid path, and a second position causing relatively lesser constriction of the fluid path. Actuating the actuator, e.g., by rotation, can deform material between the valve and the fluid path, thereby constricting at least a portion of the underlying fluid path and regulating the flow of a fluid in the fluid path. In another aspect, the invention provides a reservoir into which fluid can be placed and from which fluid can be introduced into a microfluidic system. In one embodiment, the reservoir is expandable and thereby able to store fluid under pressure for delivery to a microfluidic system.Type: ApplicationFiled: January 31, 2006Publication date: May 13, 2010Applicant: President and Fellows of Harvard collegeInventors: Douglas B. Weibel, Andrew Lee, Scott Potenta, Adam Siegel, Maarten Kruithof, George M. Whitesides
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Publication number: 20070298433Abstract: An assay method is described, which comprises the steps of immobilizing a binding partner (e.g., an antigen or antibody) for an analyte to be detected (e.g., an antibody or antigen) on a portion (140) of a surface (130) of a microfluidic chamber (120,122,124); passing a fluid sample over the surface and allowing the analyte to bind to the binding partner; allowing a metal colloid, e.g., a gold-conjugated antibody, to associate with the bound analyte; flowing a metal solution, e.g., a silver solution, over the surface such as to form an opaque metallic layer; and detecting the presence of said metallic layer, e.g., by visual inspection or by measuring light transmission through the layer, conductivity or resistance of the layer, or metal concentration in the metal solution after flowing the metal solution over the surface.Type: ApplicationFiled: December 29, 2004Publication date: December 27, 2007Applicant: PRESIDENT AND FELLOWS OF HARVARD COLLEGEInventors: Samuel Sia, Vincent Linder, Adam Siegel, George Whitesides, Babak Amir-Parviz
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Publication number: 20030220972Abstract: An instant messaging (IM) system for providing automatic IM services includes a server, at least one client connected to the server, an automatic portal unit connected to the server, and at least one automatic service unit connected to the server. If the automatic portal unit receives a service-activation input from a first client, the automatic portal unit configures a first automatic service unit to provide services to selected clients based on the service-activation input. If the first automatic service unit is configured to provide services to the selected clients, the first automatic service unit provides service responses when receiving communications from the selected clients.Type: ApplicationFiled: May 19, 2003Publication date: November 27, 2003Inventors: Ivan Montet, Eric Dalmasso, Adam Siegel